Joan Durbin, M.D., Ph.D.

Plasticity and Virus Specificity of the Airway Epithelial Cell Immune Response during Respiratory Virus Infection
Ioannidis, Ioannis; McNally, Beth; Willette, Meredith; Peeples, Mark E; Chaussabel, Damien; Durbin, Joan E; Ramilo, Octavio; Mejias, Asuncion; Flano, Emilio
2012 May;86(10):5422-5436, Journal of virology
— id: 167042, year: 2012, vol: 86, page: 5422, stat: Journal Article,

Stat1 is a suppressor of ErbB2/Neu-mediated cellular transformation and mouse mammary gland tumor formation
Raven, Jennifer F; Williams, Virginie; Wang, Shuo; Tremblay, Michel L; Muller, William J; Durbin, Joan E; Koromilas, Antonis E
2011 Mar;10(5):794-804, Cell cycle
— id: 167043, year: 2011, vol: 10, page: 794, stat: Journal Article,

Mapping the anatomy of respiratory syncytial virus infection of the upper airways in chinchillas (Chinchilla lanigera)
Grieves, Jessica L; Jurcisek, Joseph A; Quist, Brian; Durbin, Russell K; Peeples, Mark E; Durbin, Joan E; Bakaletz, Lauren O
2010 Jun;60(3):225-232, Comparative medicine
— id: 167045, year: 2010, vol: 60, page: 225, stat: Journal Article,

Lambda interferon is the predominant interferon induced by influenza A virus infection in vivo
Jewell, Nancy A; Cline, Troy; Mertz, Sara E; Smirnov, Sergey V; Flano, Emilio; Schindler, Christian; Grieves, Jessica L; Durbin, Russell K; Kotenko, Sergei V; Durbin, Joan E
2010 Nov;84(21):11515-11522, Journal of virology
— id: 167044, year: 2010, vol: 84, page: 11515, stat: Journal Article,

Differential negative regulation of type I and type III interferons underlies extended antiviral effects of interferon-lambdas
Smirnov, Sergey V.; Burkart, Christoph; Li, Wei; Lewis-Antes, Anita; Durbin, Joan; Zhang, Dong-Er; Notenko, Sergei V.
2010 OCT-NOV ;52(1-2):48-48, Cytokine
— id: 113934, year: 2010, vol: 52, page: 48, stat: Journal Article,

Signal transducer and activator of transcription 1 in T cells plays an indispensable role in immunity to Leishmania major by mediating Th1 cell homing to the site of infection
Barbi, Joseph; Snider, Heidi M; Bhardwaj, Neeti; Lezama-Davila, Claudio M; Durbin, Joan E; Satoskar, Abhay R
2009 Nov;23(11):3990-3999, FASEB journal
— id: 167046, year: 2009, vol: 23, page: 3990, stat: Journal Article,

Methods used to study respiratory virus infection
Flano, Emilio; Jewell, Nancy A; Durbin, Russell K; Durbin, Joan E
2009 Jun;Chapter 26:Unit 26.3-Unit 26.3 Unit 26.3, Current protocols in cell biology
— id: 167048, year: 2009, vol: Chapter 26, page: Unit 26.3, stat: Journal Article,

STAT1 negatively regulates lung basophil IL-4 expression induced by respiratory syncytial virus infection
Moore, Martin L; Newcomb, Dawn C; Parekh, Vrajesh V; Van Kaer, Luc; Collins, Robert D; Zhou, Weisong; Goleniewska, Kasia; Chi, Michael H; Mitchell, Daphne; Boyce, Joshua A; Durbin, Joan E; Sturkie, Carla; Peebles, R Stokes Jr
2009 Aug;183(3):2016-2026, Journal of immunology
— id: 167047, year: 2009, vol: 183, page: 2016, stat: Journal Article,

Differential regulation of GM1 and asialo-GM1 expression by T cells and natural killer (NK) cells in respiratory syncytial virus infection
Moore, Martin L; Chi, Michael H; Goleniewska, Kasia; Durbin, Joan E; Peebles, R Stokes Jr
2008 Sep;21(3):327-339, Viral immunology
— id: 167050, year: 2008, vol: 21, page: 327, stat: Journal Article,

Stat1 phosphorylation determines Ras oncogenicity by regulating p27 kip1
Wang, Shuo; Raven, Jennifer F; Durbin, Joan E; Koromilas, Antonis E
2008 ;3(10):e3476-e3476 e3476, PLoS ONE
— id: 167049, year: 2008, vol: 3, page: e3476, stat: Journal Article,

Influenza A virus inhibits alveolar fluid clearance in BALB/c mice
Wolk, Kendra E; Lazarowski, Eduardo R; Traylor, Zachary P; Yu, Erin N Z; Jewell, Nancy A; Durbin, Russell K; Durbin, Joan E; Davis, Ian C
2008 Nov;178(9):969-976, American journal of respiratory & critical care medicine
— id: 167051, year: 2008, vol: 178, page: 969, stat: Journal Article,

Respiratory virus infection in infants and children
Hammond, Sue; Chenever, Emily; Durbin, Joan E
2007 May-Jun;10(3):172-180, Pediatric & developmental pathology
— id: 167054, year: 2007, vol: 10, page: 172, stat: Journal Article,

STAT1 is involved in the pathogenesis of murine allergic rhinitis
Hattori, Hisashi; Rosas, Lucia E; Okano, Mitsuhiro; Durbin, Joan E; Nishizaki, Kazunori; Satoskar, Abhay R
2007 Mar-Apr;21(2):241-247, American journal of rhinology
— id: 167055, year: 2007, vol: 21, page: 241, stat: Journal Article,

Differential type I interferon induction by respiratory syncytial virus and influenza a virus in vivo
Jewell, Nancy A; Vaghefi, Negin; Mertz, Sara E; Akter, Parvis; Peebles, R Stokes Jr; Bakaletz, Lauren O; Durbin, Russell K; Flano, Emilio; Durbin, Joan E
2007 Sep;81(18):9790-9800, Journal of virology
— id: 167053, year: 2007, vol: 81, page: 9790, stat: Journal Article,

Recombinant parainfluenza virus 5 (PIV5) expressing the influenza A virus hemagglutinin provides immunity in mice to influenza A virus challenge
Tompkins, S Mark; Lin, Yuan; Leser, George P; Kramer, Kari A; Haas, Debra L; Howerth, Elizabeth W; Xu, Jie; Kennett, Mary J; Durbin, Russell K; Durbin, Joan E; Tripp, Ralph; Lamb, Robert A; He, Biao
2007 May;362(1):139-150, Virology
— id: 167056, year: 2007, vol: 362, page: 139, stat: Journal Article,

Type I interferon inhibition and dendritic cell activation during gammaherpesvirus respiratory infection
Weslow-Schmidt, Janet L; Jewell, Nancy A; Mertz, Sara E; Simas, J Pedro; Durbin, Joan E; Flano, Emilio
2007 Sep;81(18):9778-9789, Journal of virology
— id: 167052, year: 2007, vol: 81, page: 9778, stat: Journal Article,

Protection against respiratory syncytial virus by a recombinant Newcastle disease virus vector
Martinez-Sobrido, Luis; Gitiban, Negin; Fernandez-Sesma, Ana; Cros, Jerome; Mertz, Sara E; Jewell, Nancy A; Hammond, Sue; Flano, Emilio; Durbin, Russell K; Garcia-Sastre, Adolfo; Durbin, Joan E
2006 Feb;80(3):1130-1139, Journal of virology
— id: 167058, year: 2006, vol: 80, page: 1130, stat: Journal Article,

Cutting edge: STAT1 and T-bet play distinct roles in determining outcome of visceral leishmaniasis caused by Leishmania donovani
Rosas, Lucia E; Snider, Heidi M; Barbi, Joseph; Satoskar, Anjali A; Lugo-Villarino, Geanncarlo; Keiser, Tracy; Papenfuss, Tracy; Durbin, Joan E; Radzioch, Danuta; Glimcher, Laurie H; Satoskar, Abhay R
2006 Jul;177(1):22-25, Journal of immunology
— id: 167057, year: 2006, vol: 177, page: 22, stat: Journal Article,

STAT-1-mediated repression of monocyte interleukin-10 gene expression in vivo
VanDeusen, Jeffrey B; Shah, Manisha H; Becknell, Brian; Blaser, Bradley W; Ferketich, Amy K; Nuovo, Gerard J; Ahmer, Brian M M; Durbin, Joan; Caligiuri, Michael A
2006 Mar;36(3):623-630, European journal of immunology
— id: 232242, year: 2006, vol: 36, page: 623, stat: Journal Article,

IL-13 is associated with reduced illness and replication in primary respiratory syncytial virus infection in the mouse
Zhou, Weisong; Hashimoto, Koichi; Moore, Martin L; Elias, Jack A; Zhu, Zhou; Durbin, Joan; Colasurdo, Giuseppe; Rutigliano, John A; Chiappetta, Constance L; Goleniewska, Kasia; O'Neal, Jamye F; Graham, Barney S; Peebles, R Stokes Jr
2006 Nov-Dec;8(14-15):2880-2889, Microbes & infection
— id: 232232, year: 2006, vol: 8, page: 2880, stat: Journal Article,

TNF receptor-associated factor 6-dependent CD40 signaling primes macrophages to acquire antimicrobial activity in response to TNF-alpha
Andrade, Rosa M; Wessendarp, Matthew; Portillo, Jose-Andres C; Yang, Jun-Qi; Gomez, Francisco J; Durbin, Joan E; Bishop, Gail A; Subauste, Carlos S
2005 Nov;175(9):6014-6021, Journal of immunology
— id: 167059, year: 2005, vol: 175, page: 6014, stat: Journal Article,

Chinchilla and murine models of upper respiratory tract infections with respiratory syncytial virus
Gitiban, Negin; Jurcisek, Joseph A; Harris, Randall H; Mertz, Sara E; Durbin, Russell K; Bakaletz, Lauren O; Durbin, Joan E
2005 May;79(10):6035-6042, Journal of virology
— id: 167062, year: 2005, vol: 79, page: 6035, stat: Journal Article,

Respiratory syncytial virus infection in the absence of STAT 1 results in airway dysfunction, airway mucus, and augmented IL-17 levels
Hashimoto, Koichi; Durbin, Joan E; Zhou, Weisong; Collins, Robert D; Ho, Samuel B; Kolls, Jay K; Dubin, Patricia J; Sheller, James R; Goleniewska, Kasia; O'Neal, Jamye F; Olson, Sandra J; Mitchell, Daphne; Graham, Barney S; Peebles, R Stokes Jr
2005 Sep;116(3):550-557, Journal of allergy & clinical immunology
— id: 167060, year: 2005, vol: 116, page: 550, stat: Journal Article,

Role for innate IFNs in determining respiratory syncytial virus immunopathology
Johnson, Teresa R; Mertz, Sara E; Gitiban, Negin; Hammond, Sue; Legallo, Robin; Durbin, Russell K; Durbin, Joan E
2005 Jun;174(11):7234-7241, Journal of immunology
— id: 167061, year: 2005, vol: 174, page: 7234, stat: Journal Article,

Respiratory syncytial virus-induced immunoprotection and immunopathology
Durbin, Joan E; Durbin, Russell K
2004 ;17(3):370-380, Viral immunology
— id: 167063, year: 2004, vol: 17, page: 370, stat: Journal Article,

Activation induced differential regulation of stem cell antigen-1 (Ly-6A/E) expression in murine B cells
Chen, Hui-Chen; Frissora, Frank; Durbin, Joan E; Muthusamy, Natarajan
2003 Sep;225(1):42-52, Cellular immunology
— id: 167064, year: 2003, vol: 225, page: 42, stat: Journal Article,

The role of STAT1 in viral sensitization to LPS
Durbin, Joan; Doughty, Leslie; Nguyen, Ken; Caligiuri, Michael; Van Deusen, Jeff; Biron, Christine
2003 ;9(5):313-316, Journal of endotoxin research
— id: 232252, year: 2003, vol: 9, page: 313, stat: Journal Article,

IFN-gamma-mediated inhibition of antigen receptor-induced B cell proliferation and CREB-1 binding activity requires STAT-1 transcription factor
Frissora, Frank; Chen, Hui-Chen; Durbin, Joan; Bondada, Subbarao; Muthusamy, Natarajan
2003 Apr;33(4):907-912, European journal of immunology
— id: 232292, year: 2003, vol: 33, page: 907, stat: Journal Article,

Differentiation of monocytic cell clones into CD8 alpha+ dendritic cells (DC) suggests that monocytes can be direct precursors for both CD8 alpha+ and CD8 alpha- DC in the mouse
Gao, Jian-Xin; Liu, Xingluo; Wen, Jing; Zhang, Huiming; Durbin, Joan; Liu, Yang; Zheng, Pan
2003 Jun;170(12):5927-5935, Journal of immunology
— id: 232282, year: 2003, vol: 170, page: 5927, stat: Journal Article,

Anatomy of the nasal cavity in the chinchilla
Jurcisek, Joseph A; Durbin, Joan E; Kusewitt, Donna F; Bakaletz, Lauren O
2003 ;174(3):136-152, Cells tissues organs
— id: 167066, year: 2003, vol: 174, page: 136, stat: Journal Article,

The antitumor effects of IFN-alpha are abrogated in a STAT1-deficient mouse
Lesinski, Gregory B; Anghelina, Mirela; Zimmerer, Jason; Bakalakos, Timothy; Badgwell, Brian; Parihar, Robin; Hu, Yan; Becknell, Brian; Abood, Gerard; Chaudhury, Abhik Ray; Magro, Cynthia; Durbin, Joan; Carson, William E 3rd
2003 Jul;112(2):170-180, Journal of clinical investigation
— id: 232262, year: 2003, vol: 112, page: 170, stat: Journal Article,

Development of protective immunity against cutaneous leishmaniasis is dependent on STAT1-mediated IFN signaling pathway
Rosas, Lucia E; Keiser, Tracy; Pyles, Ryan; Durbin, Joan; Satoskar, Abhay R
2003 Jul;33(7):1799-1805, European journal of immunology
— id: 232272, year: 2003, vol: 33, page: 1799, stat: Journal Article,

VSV strains with defects in their ability to shutdown innate immunity are potent systemic anti-cancer agents
Stojdl, David F; Lichty, Brian D; tenOever, Benjamin R; Paterson, Jennifer M; Power, Anthony T; Knowles, Shane; Marius, Ricardo; Reynard, Jennifer; Poliquin, Laurent; Atkins, Harold; Brown, Earl G; Durbin, Russell K; Durbin, Joan E; Hiscott, John; Bell, John C
2003 Oct;4(4):263-275, Cancer cell
— id: 167065, year: 2003, vol: 4, page: 263, stat: Journal Article,

The role of IFN in respiratory syncytial virus pathogenesis
Durbin, Joan E; Johnson, Teresa R; Durbin, Russell K; Mertz, Sara E; Morotti, Rafaella A; Peebles, R Stokes; Graham, Barney S
2002 Mar;168(6):2944-2952, Journal of immunology
— id: 167070, year: 2002, vol: 168, page: 2944, stat: Journal Article,

PKR protection against intranasal vesicular stomatitis virus infection is mouse strain dependent
Durbin, R K; Mertz, S E; Koromilas, A E; Durbin, J E
2002 ;15(1):41-51, Viral immunology
— id: 167069, year: 2002, vol: 15, page: 41, stat: Journal Article,

Cis elements for transporter associated with antigen-processing-2 transcription: two new promoters and an essential role of the IFN response factor binding element in IFN-gamma-mediated activation of the transcription initiator
Guo, Yong; Yang, Tianyu; Liu, Xingluo; Lu, Shengli; Wen, Jing; Durbin, Joan E; Liu, Yang; Zheng, Pan
2002 Feb;14(2):189-200, International immunology
— id: 167071, year: 2002, vol: 14, page: 189, stat: Journal Article,

Recovery of paramyxovirus simian virus 5 with a V protein lacking the conserved cysteine-rich domain: the multifunctional V protein blocks both interferon-beta induction and interferon signaling
He, Biao; Paterson, Reay G; Stock, Nicola; Durbin, Joan E; Durbin, Russell K; Goodbourn, Stephen; Randall, Richard E; Lamb, Robert A
2002 Nov;303(1):15-32, Virology
— id: 167067, year: 2002, vol: 303, page: 15, stat: Journal Article,

Coordinated and distinct roles for IFN-alpha beta, IL-12, and IL-15 regulation of NK cell responses to viral infection
Nguyen, Khuong B; Salazar-Mather, Thais P; Dalod, Marc Y; Van Deusen, Jeffrey B; Wei, Xiao-qing; Liew, Foo Y; Caligiuri, Michael A; Durbin, Joan E; Biron, Christine A
2002 Oct;169(8):4279-4287, Journal of immunology
— id: 167068, year: 2002, vol: 169, page: 4279, stat: Journal Article,

The SH integral membrane protein of the paramyxovirus simian virus 5 is required to block apoptosis in MDBK cells
He, B; Lin, G Y; Durbin, J E; Durbin, R K; Lamb, R A
2001 May;75(9):4068-4079, Journal of virology
— id: 167072, year: 2001, vol: 75, page: 4068, stat: Journal Article,

Enhanced antiviral and antiproliferative properties of a STAT1 mutant unable to interact with the protein kinase PKR
Wong, A H; Durbin, J E; Li, S; Dever, T E; Decker, T; Koromilas, A E
2001 Apr;276(17):13727-13737, Journal of biological chemistry
— id: 167073, year: 2001, vol: 276, page: 13727, stat: Journal Article,

Control of Sindbis virus infection by antibody in interferon-deficient mice
Byrnes, A P; Durbin, J E; Griffin, D E
2000 Apr;74(8):3905-3908, Journal of virology
— id: 167075, year: 2000, vol: 74, page: 3905, stat: Journal Article,

Type I IFN modulates innate and specific antiviral immunity
Durbin JE; Fernandez-Sesma A; Lee CK; Rao TD; Frey AB; Moran TM; Vukmanovic S; Garcia-Sastre A; Levy DE
2000 Apr 15;164(8):4220-4228, Journal of immunology
— id: 11766, year: 2000, vol: 164, page: 4220, stat: Journal Article,

Interferon alpha/beta-mediated inhibition and promotion of interferon gamma: STAT1 resolves a paradox
Nguyen, K B; Cousens, L P; Doughty, L A; Pien, G C; Durbin, J E; Biron, C A
2000 Jul;1(1):70-76, Nature immunology
— id: 167074, year: 2000, vol: 1, page: 70, stat: Journal Article,

The role of interferon in influenza virus tissue tropism
Garcia-Sastre A; Durbin RK; Zheng H; Palese P; Gertner R; Levy DE; Durbin JE
1998 Nov;72(11):8550-8558, Journal of virology
— id: 7576, year: 1998, vol: 72, page: 8550, stat: Journal Article,

Resistance to influenza virus infection is mediated by STAT1
Garcia-Sastre, A; Durbin, RK; Zheng, HY; Palese, P; Levy, DE; Durbin, JE
1998 SEP ;9(3):398-398, European cytokine network
— id: 53663, year: 1998, vol: 9, page: 398, stat: Journal Article,

Influenza A virus lacking the NS1 gene replicates in interferon-deficient systems
Garcia-Sastre, A; Egorov, A; Matassov, D; Brandt, S; Levy, D E; Durbin, J E; Palese, P; Muster, T
1998 Dec 20;252(2):324-330, Virology
— id: 138967, year: 1998, vol: 252, page: 324, stat: Journal Article,

Differential viral induction of distinct interferon-alpha genes by positive feedback through interferon regulatory factor-7
Marie I; Durbin JE; Levy DE
1998 Nov 16;17(22):6660-6669, EMBO journal
— id: 7964, year: 1998, vol: 17, page: 6660, stat: Journal Article,

Human cytomegalovirus inhibits major histocompatibility complex class II expression by disruption of the Jak/Stat pathway
Miller, D M; Rahill, B M; Boss, J M; Lairmore, M D; Durbin, J E; Waldman, J W; Sedmak, D D
1998 Mar;187(5):675-683, Journal of experimental medicine
— id: 167076, year: 1998, vol: 187, page: 675, stat: Journal Article,

The role of interferon (IFN) in the pathogenesis of influenza virus infection
Durbin, J; Levy, D; Greco, A; Garcia, A; Palese, P; Fernandez, A; Moran, T; Qualman, S
1997 ;76(Suppl 1):10-10, Laboratory investigation
— id: 53332, year: 1997, vol: 76, page: 10, stat: Journal Article,

ISGF3 gamma p48, a specificity switch for interferon activated transcription factors
Bluyssen AR; Durbin JE; Levy DE
1996 Jun;7(1):11-17, Cytokine & growth factor reviews
— id: 12594, year: 1996, vol: 7, page: 11, stat: Journal Article,

Gastrin-releasing peptide in hypoplastic lungs
Durbin J; Thomas P; Langston C; Goswami S; Greco MA
1996 Nov-Dec;16(6):927-934, Pediatric pathology & laboratory medicine
— id: 12479, year: 1996, vol: 16, page: 927, stat: Journal Article,

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease
Durbin JE; Hackenmiller R; Simon MC; Levy DE
1996 Feb 9;84(3):443-450, Cell
— id: 6903, year: 1996, vol: 84, page: 443, stat: Journal Article,

Growth fraction determination in pulmonary hypoplasia using Ki-67 (MIB-1) antibody
Thomas, PA; Durbin, J; Langston, C; Raab, SS; Jagirdar, J; Greco, MA
1996 SEP-OCT ;16(5):745-753, Pediatric pathology & laboratory medicine
— id: 52802, year: 1996, vol: 16, page: 745, stat: Journal Article,

Cytoplasmic transcription factors: mediators of cytokine signaling
Levy DE; Raz R; Durbin JE; Bluyssen H; Muzaffar R; Pisharody S
1995 ;47:79-85, Agents & actions. Supplements
— id: 12847, year: 1995, vol: 47, page: 79, stat: Journal Article,

Acute phase response factor and additional members of the interferon-stimulated gene factor 3 family integrate diverse signals from cytokines, interferons, and growth factors
Raz R; Durbin JE; Levy DE
1994 Sep 30;269(39):24391-24395, Journal of biological chemistry
— id: 12890, year: 1994, vol: 269, page: 24391, stat: Journal Article,

Identification of cDNAs corresponding to mosquito ribosomal protein genes
Durbin, J E; Swerdel, M R; Fallon, A M
1988 Jul;950(2):182-192, Biochimica & biophysica acta
— id: 167077, year: 1988, vol: 950, page: 182, stat: Journal Article,

Transient expression of the chloramphenicol acetyltransferase gene in cultured mosquito cells
Durbin, J E; Fallon, A M
1985 ;36(1-2):173-178, Gene
— id: 167078, year: 1985, vol: 36, page: 173, stat: Journal Article,