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Maria Dominguez-Bello

Associate Professor, Department of Medicine

Contact Info

Address
462 First Avenue
New York, NY 10016

646/501-0703
Maria.Dominguez-Bello@nyumc.org

Research Summary

My research has been focused for the last years on the microbiota function in vertebrate animals and humans, microbiota development and impact of modern practices, integrating data from microbiology, genomics/metagenomics, ecology, physiology, anthropology, architecture, environmental engineering and biostatistics to address broad questions on host-microbial interactions in different environments. The focus is on how these interactions drive microbial evolution, diversity and symbiosis. We study the bacterial microbiota in vertebrates, including birds and mammals, and we have lead studies using next-gen sequencing of the human microbiome in peoples with different levels of integration to Western lifestyles, in the Amazon region and southern Africa. We have a strong team of collaborators that include among others Rob Knight (U. Colorado), Jeff Gordon (Washington U.), Martin Blaser (NYU), Suzanne Tringe (DOE-Joint Genome Institute), Gary Andersen (Lawrence Berkeley Nat'l Lab), Monica Contreras (Venezuelan InstSci Research-IVIC), Magda Magris (Amazonic Center for Research In Tropical Diseases- CAICET, Venezuela), Jean Hernandez (INS Loreto, Iquitos, Peru), Henrique Pereira (Univ. Federal Amazonas, Manaus, Brazil).

Research Interests

Host-microbial interactions in different environments; how these interactions drive microbial evolution, diversity and symbiosis; we study the bacterial microbiota in vertebrates, including birds and mammals, using next-gen sequencing of the human microbiome in peoples with different levels of integration to Western lifestyles, in the Amazonas and southern Africa. Visit the Dominguez-Bello Lab webpage:
http://medicine.med.nyu.edu/clinicalpharm/research/dominguez-bello-lab

Antibiotics, birth mode, and diet shape microbiome maturation during early life
Bokulich, Nicholas A; Chung, Jennifer; Battaglia, Thomas; Henderson, Nora; Jay, Melanie; Li, Huilin; D Lieber, Arnon; Wu, Fen; Perez-Perez, Guillermo I; Chen, Yu; Schweizer, William; Zheng, Xuhui; Contreras, Monica; Dominguez-Bello, Maria Gloria; Blaser, Martin J. Antibiotics, birth mode, and diet shape microbiome maturation during early life. Science translational medicine. 2016 Jun 15;8(343):343ra82-343ra82 343ra82 (2143372)

Safety of vaginal microbial transfer in infants delivered by caesarean, and expected health outcomes
Clemente, Jose C; Dominguez-Bello, Maria Gloria. Safety of vaginal microbial transfer in infants delivered by caesarean, and expected health outcomes [Letter]. British medical journal. BMJ (Clinical research ed.). 2016 Mar 31;352:i1707-i1707 i1707 (2079692)

Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer
Dominguez-Bello, Maria G; De Jesus-Laboy, Kassandra M; Shen, Nan; Cox, Laura M; Amir, Amnon; Gonzalez, Antonio; Bokulich, Nicholas A; Song, Se Jin; Hoashi, Marina; Rivera-Vinas, Juana I; Mendez, Keimari; Knight, Rob; Clemente, Jose C. Partial restoration of the microbiota of cesarean-born infants via vaginal microbial transfer. Nature medicine. 2016 Feb 1;22(3):250-253 (1933522)

Birth mode-dependent association between pre-pregnancy maternal weight status and the neonatal intestinal microbiome
Mueller, Noel T; Shin, Hakdong; Pizoni, Aline; Werlang, Isabel C; Matte, Ursula; Goldani, Marcelo Z; Goldani, Helena A S; Dominguez-Bello, Maria Gloria. Birth mode-dependent association between pre-pregnancy maternal weight status and the neonatal intestinal microbiome. Scientific reports. 2016 Apr 1;6:23133-23133 (2059292)

The Gestational Vaginal Microbiome and Spontaneous Preterm Birth among Nulliparous African American Women
Nelson, Deborah B; Shin, Hakdong; Wu, Jingwei; Dominguez-Bello, Maria G. The Gestational Vaginal Microbiome and Spontaneous Preterm Birth among Nulliparous African American Women. American journal of perinatology. 2016 Apr 8;33(9):887-893 (2066282)