Stuart A Dickerman, M.D.

INFLUENCE OF TIME OF CARDIAC SURGERY (CS) ON THE OUTCOME OF PATIENTS WITH INFECTIVE ENDOCARDITIS (IE) AND STROKE
Barsic, B; Dickerman, S; Bayer, A; Delahaye, F; Chu, V; Hsieh, E; Krajinovic, V; Olaison, L; Vincelj, J; Wang, A
2009 APR ;33(1):S38-S38, International journal of antimicrobial agents
— id: 100041, year: 2009, vol: 33, page: S38, stat: Journal Article,

Therapeutic Levels of Anticoagulation Do Not Increase Embolic Risk Early in the Course of S. Aureus Infective Endocarditis
Dickerman, S; Gunn, M; Barsic, B; Halim, M; Chu, V; Corey, R; Hsieh, TC; Bayer, A
2009 NOV 3 ;120(18):S308-S308, Circulation
— id: 106968, year: 2009, vol: 120, page: S308, stat: Journal Article,

The relationship between the initiation of antimicrobial therapy and the incidence of stroke in infective endocarditis: an analysis from the ICE Prospective Cohort Study (ICE-PCS)
Dickerman, Stuart A; Abrutyn, Elias; Barsic, Bruno; Bouza, Emilio; Cecchi, Enrico; Moreno, Asuncion; Doco-Lecompte, Thanh; Eisen, Damon P; Fortes, Claudio Q; Fowler, Vance G Jr; Lerakis, Stamatios; Miro, Jose M; Pappas, Paul; Peterson, Gail E; Rubinstein, Ethan; Sexton, Daniel J; Suter, Fredy; Tornos, Pilar; Verhagen, Dominique W; Cabell, Christopher H
2007 Dec;154(6):1086-1094, American heart journal
BACKGROUND: Embolic events to the central nervous system are a major cause of morbidity and mortality in patients with infective endocarditis (IE). The appropriate role of valvular surgery in reducing such embolic events is unclear. The purpose of this study was to determine the relationship between the initiation of antimicrobial therapy and the temporal incidence of stroke in patients with IE and to determine if this time course differs from that shown for embolic events in previous studies. METHODS: Prospective incidence cohort study involving 61 tertiary referral centers in 28 countries. Case report forms were analyzed from 1437 consecutive patients with left-sided endocarditis admitted directly to participating centers. RESULTS: The crude incidence of stroke in patients receiving appropriate antimicrobial therapy was 4.82/1000 patient days in the first week of therapy and fell to 1.71/1000 patient days in the second week. This rate continued to decline with further therapy. Stroke rates fell similarly regardless of the valve or organism involved. After 1 week of antimicrobial therapy, only 3.1% of the cohort experienced a stroke. CONCLUSIONS: The risk of stroke in IE falls dramatically after the initiation of effective antimicrobial therapy. The falling risk of stroke in patients with IE as a whole precludes stroke prevention as the sole indication for valvular surgery after 1 week of therapy
— id: 75408, year: 2007, vol: 154, page: 1086, stat: Journal Article,

Non-HACEK gram-negative bacillus endocarditis
Morpeth, S; Murdoch, D; Cabell, CH; Karchmer, AW; Pappas, P; Levine, D; Nacinovich, F; Tattevin, P; Fernandez-Hidalgo, N; Dickerman, S; Bouza, E; Del Rio, A; Lejko-Zupanc, T; Ramos, ADO; Larussi, D; Klein, J; Chirouze, C; Bedimo, R; Corey, GR; Fowler, VG
2007 DEC 18 ;147(12):829-835, Annals of internal medicine
Background: Infective endocarditis caused by non-HACEK (species other than Haemophilus species, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, or Kingella species) gram-negative bacilli is rare, is poorly characterized, and is commonly considered to be primarily a disease of injection drug users. Objective: To describe the clinical characteristics and outcomes of patients with non-HACEK gram-negative bacillus endocarditis in a large, international, contemporary cohort of patients. Design: Observations from the International Collaboration on Infective Endocarditis Prospective Cohort Study (ICE-PCS) database. Setting: 61 hospitals in 28 countries. Patients: Hospitalized patients with definite endocarditis. Measurements: Characteristics of non-HACEK gram-negative bacillus endocarditis cases were described and compared with those due to other pathogens. Results: Among the 2761 case-patients with definite endocarditis enrolled in ICE-PCS, 49 (1.8%) had endocarditis (20 native valve, 29 prosthetic valve or device) due to non-HACEK, gram-negative bacilli. Escherichia coli (14 patients [29%]) and Pseudomonas aeruginosa (11 patients [22%]) were the most common pathogens. Most patients (57%) with non-HACEK gram-negative bacillus endocarditis had health care-associated infection, whereas injection drug use was rare (4%). Implanted endovascular devices were frequently associated with non-HACEK gram-negative bacillus endocarditis compared with other causes of endlocarditis (29% vs. 11%; P < 0.001). The in-hospital mortality rate of patients with enclocarditis due to non-HACEK gram-negative bacilli was high (24%) despite high rates of cardiac surgery (51%). Limitations: Because of the small number of patients with non-HACEK gram-negative bacillus endocarditis in each treatment group and the lack of long-term follow-up, strong treatment recommendations are difficult to make. Conclusion: in this large, prospective, multinational cohort, more than one half of all cases of non-HACEK gram-negative bacillus enclocarditis were associated with health care contact. Non-HACEK gram-negative bacillus enclocarditis is not primarily a disease of injection drug users
— id: 75635, year: 2007, vol: 147, page: 829, stat: Journal Article,

Mitral and tricuspid valve regurgitation in dilated cardiomyopathy
Dickerman SA; Rubler S
1989 Mar 1;63(9):629-631, American journal of cardiology
— id: 10703, year: 1989, vol: 63, page: 629, stat: Journal Article,

Ileocecal tuberculosis in a patient with the acquired immune deficiency syndrome
Dickerman SA; Sherman A; Balthazar EJ; Hazzi C
1987 Nov;83(5):1010-1011, American journal of medicine
— id: 43891, year: 1987, vol: 83, page: 1010, stat: Journal Article,