Nicholas J Cowan

Biosketch / Results /

Nicholas J Cowan, Ph.D.

Professor;
Departments of Biochemistry and Molecular Pharmacology (Biochemistry) and Biochemistry and Molecular Pharmacology

Contact Info

Address
550 First Avenue
Department of Biochemistry Floor 3 Room 315
Medical Science Building
New York, NY 10016

212-263-8166
Nicholas.Cowan@nyumc.org

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Education

1967-1970 — University of Oxford, England, PhD in Biochemistry, Graduate Education
1970-1973 — Medical Research Council Laboratory of Molecular Biology, Cambridge, England, PostDoctoral Training

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Mutations in TUBG1, DYNC1H1, KIF5C and KIF2A cause malformations of cortical development and microcephaly
Poirier, Karine; Lebrun, Nicolas; Broix, Loic; Tian, Guoling; Saillour, Yoann; Boscheron, Cecile; Parrini, Elena; Valence, Stephanie; Pierre, Benjamin Saint; Oger, Madison; Lacombe, Didier; Genevieve, David; Fontana, Elena; Darra, Franscesca; Cances, Claude; Barth, Magalie; Bonneau, Dominique; Bernadina, Bernardo Dalla; N'guyen, Sylvie; Gitiaux, Cyril; Parent, Philippe; des Portes, Vincent; Pedespan, Jean Michel; Legrez, Victoire; Castelnau-Ptakine, Laetitia; Nitschke, Patrick; Hieu, Thierry; Masson, Cecile; Zelenika, Diana; Andrieux, Annie; Francis, Fiona; Guerrini, Renzo; Cowan, Nicholas J; Bahi-Buisson, Nadia; Chelly, Jamel
2013 Apr;45(6):639-647, Nature genetics
— id: 394952, year: 2013, vol: 45, page: 639, stat: Journal Article,

Tubulin-Specific Chaperones: Components of a Molecular Machine That Assembles the alpha/beta Heterodimer
Tian, Guoling; Cowan, Nicholas J
2013 ;115:155-171, Methods in cell biology
— id: 512962, year: 2013, vol: 115, page: 155, stat: Journal Article,

Mutations in the beta-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities
Breuss, Martin; Heng, Julian Ik-Tsen; Poirier, Karine; Tian, Guoling; Jaglin, Xavier Hubert; Qu, Zhengdong; Braun, Andreas; Gstrein, Thomas; Ngo, Linh; Haas, Matilda; Bahi-Buisson, Nadia; Moutard, Marie-Laure; Passemard, Sandrine; Verloes, Alain; Gressens, Pierre; Xie, Yunli; Robson, Kathryn J H; Rani, Deepa Selvi; Thangaraj, Kumarasamy; Clausen, Tim; Chelly, Jamel; Cowan, Nicholas Justin; Keays, David Anthony
2012 Dec;2(6):1554-1562, Cell reports
— id: 249192, year: 2012, vol: 2, page: 1554, stat: Journal Article,

Regulation of Androgen Receptor-Mediated Transcription by RPB5 Binding Protein URI/RMP
Mita, Paolo; Savas, Jeffrey N; Djouder, Nabil; Yates, John R 3rd; Ha, Susan; Ruoff, Rachel; Schafler, Eric D; Nwachukwu, Jerome C; Tanese, Naoko; Cowan, Nicholas J; Zavadil, Jiri; Garabedian, Michael J; Logan, Susan K
2011 Sep;31(17):3639-3652, Molecular & cellular biology
— id: 136514, year: 2011, vol: 31, page: 3639, stat: Journal Article,

Tuba8 Is Expressed at Low Levels in the Developing Mouse and Human Brain
Braun, A; Breuss, M; Salzer, MC; Flint, J; Cowan, NJ; Keays, DA
2010 MAY 14 ;86(5):819-822, American journal of human genetics
— id: 110005, year: 2010, vol: 86, page: 819, stat: Journal Article,

Disease-associated mutations in TUBA1A result in a spectrum of defects in the tubulin folding and heterodimer assembly pathway
Tian, Guoling; Jaglin, Xavier H; Keays, David A; Francis, Fiona; Chelly, Jamel; Cowan, Nicholas J
2010 Sep 15;19(18):3599-3613, Human molecular genetics
— id: 112037, year: 2010, vol: 19, page: 3599, stat: Journal Article,

Effect of TBCD and its regulatory interactor Arl2 on tubulin and microtubule integrity
Tian, Guoling; Thomas, Simi; Cowan, Nicholas J
2010 Nov;67(11):706-714, Cytoskeleton (Hoboken)
— id: 113945, year: 2010, vol: 67, page: 706, stat: Journal Article,

Mutations in the beta-tubulin gene TUBB2B result in asymmetrical polymicrogyria
Jaglin, Xavier Hubert; Poirier, Karine; Saillour, Yoann; Buhler, Emmanuelle; Tian, Guoling; Bahi-Buisson, Nadia; Fallet-Bianco, Catherine; Phan-Dinh-Tuy, Francoise; Kong, Xiang Peng; Bomont, Pascale; Castelnau-Ptakhine, Laetitia; Odent, Sylvie; Loget, Philippe; Kossorotoff, Manoelle; Snoeck, Irina; Plessis, Ghislaine; Parent, Philippe; Beldjord, Cherif; Cardoso, Carlos; Represa, Alfonso; Flint, Jonathan; Keays, David Anthony; Cowan, Nicholas Justin; Chelly, Jamel
2009 Jun;41(6):746-752, Nature genetics
— id: 135247, year: 2009, vol: 41, page: 746, stat: Journal Article,

A Pachygyria-causing {alpha}-Tubulin Mutation Results in Inefficient Cycling with CCT and a Deficient Interaction with TBCB
Tian, Guoling; Kong, Xiang-Peng; Jaglin, Xavier H; Chelly, Jamel; Keays, David; Cowan, Nicholas J
2008 Mar;19(3):1152-1161, Molecular biology of the cell
— id: 78375, year: 2008, vol: 19, page: 1152, stat: Journal Article,

Mutations in alpha-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans
Keays, David A; Tian, Guoling; Poirier, Karine; Huang, Guo-Jen; Siebold, Christian; Cleak, James; Oliver, Peter L; Fray, Martin; Harvey, Robert J; Molnar, Zoltan; Pinon, Maria C; Dear, Neil; Valdar, William; Brown, Steve D M; Davies, Kay E; Rawlins, J Nicholas P; Cowan, Nicholas J; Nolan, Patrick; Chelly, Jamel; Flint, Jonathan
2007 Jan 12;128(1):45-57, Cell
— id: 78376, year: 2007, vol: 128, page: 45, stat: Journal Article,

Cryptic out-of-frame translational initiation of TBCE rescues tubulin formation in compound heterozygous HRD
Tian, Guoling; Huang, Melissa C; Parvari, Ruti; Diaz, George A; Cowan, Nicholas J
2006 Sep 5;103(36):13491-13496, Proceedings of the National Academy of Sciences of the United States of America
— id: 67543, year: 2006, vol: 103, page: 13491, stat: Journal Article,

Mutations affecting beta-tubulin folding and degradation
Wang, Yaqing; Tian, Guoling; Cowan, Nicholas J; Cabral, Fernando
2006 May 12;281(19):13628-13635, Journal of biological chemistry
— id: 67544, year: 2006, vol: 281, page: 13628, stat: Journal Article,

Identification of a novel tubulin-destabilizing protein related to the chaperone cofactor E
Bartolini, Francesca; Tian, Guoling; Piehl, Michelle; Cassimeris, Lynne; Lewis, Sally A; Cowan, Nicholas J
2005 Mar 15;118(Pt 6):1197-1207, Journal of cell science
— id: 56011, year: 2005, vol: 118, page: 1197, stat: Journal Article,

Selective contribution of eukaryotic prefoldin subunits to actin and tubulin binding
Simons, C Torrey; Staes, An; Rommelaere, Heidi; Ampe, Christophe; Lewis, Sally A; Cowan, Nicholas J
2004 Feb 6;279(6):4196-4203, Journal of biological chemistry
— id: 42643, year: 2004, vol: 279, page: 4196, stat: Journal Article,

Cytosolic Arl2 is complexed with cofactor D and protein phosphatase 2A
Shern, Jack F; Sharer, J Daniel; Pallas, David C; Bartolini, Francesca; Cowan, Nicholas J; Reed, Matthew S; Pohl, Jan; Kahn, Richard A
2003 Oct 17;278(42):40829-40836, Journal of biological chemistry
— id: 48114, year: 2003, vol: 278, page: 40829, stat: Journal Article,

Functional overlap between retinitis pigmentosa 2 protein and the tubulin-specific chaperone cofactor C
Bartolini, Francesca; Bhamidipati, Arunashree; Thomas, Scott; Schwahn, Uwe; Lewis, Sally A; Cowan, Nicholas J
2002 Apr 26;277(17):14629-14634, Journal of biological chemistry
— id: 67547, year: 2002, vol: 277, page: 14629, stat: Journal Article,

Localization in the human retina of the X-linked retinitis pigmentosa protein RP2, its homologue cofactor C and the RP2 interacting protein Arl3
Grayson, Celene; Bartolini, Francesca; Chapple, J Paul; Willison, Keith R; Bhamidipati, Arunashree; Lewis, Sally A; Luthert, Philip J; Hardcastle, Alison J; Cowan, Nicholas J; Cheetham, Michael E
2002 Nov 15;11(24):3065-3074, Human molecular genetics
— id: 67546, year: 2002, vol: 11, page: 3065, stat: Journal Article,

Bad chaperone
Lewis, Sally A; Cowan, Nicholas J
2002 Nov;8(11):1202-1203, Nature medicine
— id: 63336, year: 2002, vol: 8, page: 1202, stat: Journal Article,

Structure of eukaryotic prefoldin and of its complexes with unfolded actin and the cytosolic chaperonin CCT
Martin-Benito, Jaime; Boskovic, Jasminka; Gomez-Puertas, Paulino; Carrascosa, Jose L; Simons, C Torrey; Lewis, Sally A; Bartolini, Francesca; Cowan, Nicholas J; Valpuesta, Jose M
2002 Dec 2;21(23):6377-6386, EMBO journal
— id: 67545, year: 2002, vol: 21, page: 6377, stat: Journal Article,

Type II chaperonins, prefoldin, and the tubulin-specific chaperones
Cowan NJ; Lewis SA
2001 ;59(2):73-104, Advances in protein chemistry
— id: 32463, year: 2001, vol: 59, page: 73, stat: Journal Article,

ADP ribosylation factor-like protein 2 (Arl2) regulates the interaction of tubulin-folding cofactor D with native tubulin
Bhamidipati A; Lewis SA; Cowan NJ
2000 May 29;149(5):1087-1096, Journal of cell biology
— id: 11674, year: 2000, vol: 149, page: 1087, stat: Journal Article,

The development of auditory attention in children
Gomes, H; Molholm, S; Christodoulou, C; Ritter, W; Cowan, N
2000 Jan 1;5:D108-D120, Frontiers in biosciences
— id: 129227, year: 2000, vol: 5, page: D108, stat: Journal Article,

Mismatch negativity in children and adults, and effects of an attended task
Gomes, H; Molholm, S; Ritter, W; Kurtzberg, D; Cowan, N; Vaughan, H G Jr
2000 Nov;37(6):807-816, Psychophysiology
— id: 129228, year: 2000, vol: 37, page: 807, stat: Journal Article,

Purification of prefoldin
Lewis, S A; Cowan, N J
2000 ;140:179-184, Methods in molecular biology
— id: 78378, year: 2000, vol: 140, page: 179, stat: Journal Article,

A chaperone with a hydrophilic surface
Cowan NJ; Lewis SA
1999 Nov;6(11):990-991, Nature structural biology
— id: 11910, year: 1999, vol: 6, page: 990, stat: Journal Article,

Prefoldin-nascent chain complexes in the folding of cytoskeletal proteins
Hansen WJ; Cowan NJ; Welch WJ
1999 Apr 19;145(2):265-277, Journal of cell biology
— id: 17132, year: 1999, vol: 145, page: 265, stat: Journal Article,

A single-ring mitochondrial chaperonin (Hsp60-Hsp10) can substitute for GroEL-GroES in vivo
Nielsen KL; McLennan N; Masters M; Cowan NJ
1999 Sep;181(18):5871-5875, Journal of bacteriology
— id: 6201, year: 1999, vol: 181, page: 5871, stat: Journal Article,

Tubulin folding cofactors as GTPase-activating proteins. GTP hydrolysis and the assembly of the alpha/beta-tubulin heterodimer
Tian G; Bhamidipati A; Cowan NJ; Lewis SA
1999 Aug 20;274(34):24054-24058, Journal of biological chemistry
— id: 6176, year: 1999, vol: 274, page: 24054, stat: Journal Article,

Mammalian cytosolic chaperonin
Cowan NJ
1998 ;290:230-241, Methods in enzymology
— id: 12142, year: 1998, vol: 290, page: 230, stat: Journal Article,

Cytoskeletal protein-prefoldin chaperone complexes form co-translationally en route to the cytosolic chaperonin and folding to the native state
Hansen, WJ; Cowan, NJ; Welch, WJ
1998 NOV ;9(11):453A-453A, Molecular biology of the cell
— id: 53651, year: 1998, vol: 9, page: 453A, stat: Journal Article,

A single ring is sufficient for productive chaperonin-mediated folding in vivo
Nielsen KL; Cowan NJ
1998 Jul;2(1):93-99, Molecular cell
— id: 7711, year: 1998, vol: 2, page: 93, stat: Journal Article,

Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin
Vainberg IE; Lewis SA; Rommelaere H; Ampe C; Vandekerckhove J; Klein HL; Cowan NJ
1998 May 29;93(5):863-873, Cell
— id: 7835, year: 1998, vol: 93, page: 863, stat: Journal Article,

The alpha- and beta-tubulin folding pathways
Lewis, S A; Tian, G; Cowan, N J
1997 Dec;7(12):479-484, Trends in cell biology
— id: 78377, year: 1997, vol: 7, page: 479, stat: Journal Article,

The ?- and ?-tubulin folding pathways
Lewis, SA; Tian, G; Cowan, NJ
1997 ;7(12):479-484, Trends in cell biology
— id: 589682, year: 1997, vol: 7, page: 479, stat: Journal Article,

Tubulin subunits exist in an activated conformational state generated and maintained by protein cofactors
Tian G; Lewis SA; Feierbach B; Stearns T; Rommelaere H; Ampe C; Cowan NJ
1997 Aug 25;138(4):821-832, Journal of cell biology
— id: 7270, year: 1997, vol: 138, page: 821, stat: Journal Article,

Chaperonin-mediated folding of actin and tubulin
Lewis SA; Tian G; Vainberg IE; Cowan NJ
1996 Jan;132(1-2):1-4, Journal of cell biology
— id: 6929, year: 1996, vol: 132, page: 1, stat: Journal Article,

GFAP is necessary for the integrity of CNS white matter architecture and long-term maintenance of myelination
Liedtke W; Edelmann W; Bieri PL; Chiu FC; Cowan NJ; Kucherlapati R; Raine CS
1996 Oct;17(4):607-615, Neuron
— id: 17133, year: 1996, vol: 17, page: 607, stat: Journal Article,

Pathway leading to correctly folded beta-tubulin
Tian G; Huang Y; Rommelaere H; Vandekerckhove J; Ampe C; Cowan NJ
1996 Jul 26;86(2):287-296, Cell
— id: 56896, year: 1996, vol: 86, page: 287, stat: Journal Article,

Quasi-native chaperonin-bound intermediates in facilitated protein folding
Tian G; Vainberg IE; Tap WD; Lewis SA; Cowan NJ
1995 Oct 13;270(41):23910-23913, Journal of biological chemistry
— id: 6872, year: 1995, vol: 270, page: 23910, stat: Journal Article,

Specificity in chaperonin-mediated protein folding
Tian G; Vainberg IE; Tap WD; Lewis SA; Cowan NJ
1995 May 18;375(6528):250-253, Nature
— id: 56720, year: 1995, vol: 375, page: 250, stat: Journal Article,

A novel cochaperonin that modulates the ATPase activity of cytoplasmic chaperonin
Gao Y; Melki R; Walden PD; Lewis SA; Ampe C; Rommelaere H; Vandekerckhove J; Cowan NJ
1994 Jun;125(5):989-996, Journal of cell biology
— id: 6381, year: 1994, vol: 125, page: 989, stat: Journal Article,

Facilitated folding of actins and tubulins occurs via a nucleotide-dependent interaction between cytoplasmic chaperonin and distinctive folding intermediates
Melki R; Cowan NJ
1994 May;14(5):2895-2904, Molecular & cellular biology
— id: 17134, year: 1994, vol: 14, page: 2895, stat: Journal Article,

THE DEVELOPMENT OF CATEGORIES AT THE SEMANTICS SYNTAX INTERFACE
BRAINE, MDS; BROOKS, PJ; COWAN, N; SAMUELS, MC; TAMISLEMONDA, C
1993 OCT-DEC ;8(4):465-494, Cognitive development
— id: 98446, year: 1993, vol: 8, page: 465, stat: Journal Article,

Two cofactors and cytoplasmic chaperonin are required for the folding of alpha- and beta-tubulin
Gao Y; Vainberg IE; Chow RL; Cowan NJ
1993 Apr;13(4):2478-2485, Molecular & cellular biology
— id: 13211, year: 1993, vol: 13, page: 2478, stat: Journal Article,

Chaperonin-mediated folding of vertebrate actin-related protein and gamma-tubulin
Melki R; Vainberg IE; Chow RL; Cowan NJ
1993 Sep;122(6):1301-1310, Journal of cell biology
— id: 6454, year: 1993, vol: 122, page: 1301, stat: Journal Article,

Eukaryotic cytosolic chaperonin contains t-complex polypeptide 1 and seven related subunits
Rommelaere H; Van Troys M; Gao Y; Melki R; Cowan NJ; Vandekerckhove J; Ampe C
1993 Dec 15;90(24):11975-11979, Proceedings of the National Academy of Sciences of the United States of America
— id: 17135, year: 1993, vol: 90, page: 11975, stat: Journal Article,

A novel 205-kilodalton testis-specific serine/threonine protein kinase associated with microtubules of the spermatid manchette
Walden PD; Cowan NJ
1993 Dec;13(12):7625-7635, Molecular & cellular biology
— id: 6548, year: 1993, vol: 13, page: 7625, stat: Journal Article,

The mechanism of equilibrium binding of microtubule-associated protein 2 to microtubules. Binding is a multi-phasic process and exhibits positive cooperativity
Wallis KT; Azhar S; Rho MB; Lewis SA; Cowan NJ; Murphy DB
1993 Jul 15;268(20):15158-15167, Journal of biological chemistry
— id: 17136, year: 1993, vol: 268, page: 15158, stat: Journal Article,

Projection domains of MAP2 and tau determine spacings between microtubules in dendrites and axons
Chen J; Kanai Y; Cowan NJ; Hirokawa N
1992 Dec 17;360(6405):674-677, Nature
— id: 17137, year: 1992, vol: 360, page: 674, stat: Journal Article,

DIFFERENTIAL FUNCTIONS OF MAP2, MAP2C AND TAU ON THE ORGANIZATION OF MICROTUBULES IN THE CELLS
CHEN, J; KANAI, Y; COWAN, N; HIROKAWA, N
1992 SEP ;3(4):A259-A259, Molecular biology of the cell
— id: 51865, year: 1992, vol: 3, page: A259, stat: Journal Article,

A cytoplasmic chaperonin that catalyzes beta-actin folding
Gao Y; Thomas JO; Chow RL; Lee GH; Cowan NJ
1992 Jun 12;69(6):1043-1050, Cell
— id: 13562, year: 1992, vol: 69, page: 1043, stat: Journal Article,

Increased microtubule stability and alpha tubulin acetylation in cells transfected with microtubule-associated proteins MAP1B, MAP2 or tau
Takemura R; Okabe S; Umeyama T; Kanai Y; Cowan NJ; Hirokawa N
1992 Dec;103(Pt 4):953-964, Journal of cell science
— id: 17138, year: 1992, vol: 103, page: 953, stat: Journal Article,

Mammalian mitochondrial chaperonin 60 functions as a single toroidal ring
Viitanen PV; Lorimer GH; Seetharam R; Gupta RS; Oppenheim J; Thomas JO; Cowan NJ
1992 Jan 15;267(2):695-698, Journal of biological chemistry
— id: 8274, year: 1992, vol: 267, page: 695, stat: Journal Article,

Tubulin dimer formation via the release of alpha- and beta-tubulin monomers from multimolecular complexes
Zabala JC; Cowan NJ
1992 ;23(3):222-230, Cell motility & the cytoskeleton
— id: 17139, year: 1992, vol: 23, page: 222, stat: Journal Article,

THE NEURONAL CYTOSKELETON - BURGOYNE,RO
COWAN, N
1991 AUG 15 ;352(6336):580-580, Nature
— id: 51568, year: 1991, vol: 352, page: 580, stat: Journal Article,

Regulation of expression of glial filament acidic protein
Sarkar S; Cowan NJ
1991 ;15:97-102, Journal of cell science. Supplement
— id: 14205, year: 1991, vol: 15, page: 97, stat: Journal Article,

INTRAGENIC SEQUENCES AFFECT THE EXPRESSION OF THE GENE ENCODING GLIAL FIBRILLARY ACIDIC PROTEIN
Sarkar, S; Cowan, NJ
1991 Aug;57(2):675-684, Journal of neurochemistry
— id: 32165, year: 1991, vol: 57, page: 675, stat: Journal Article,

Microtubule bundling
Lewis, S A; Cowan, N
1990 Jun;345(6277):674-674, Nature
— id: 582172, year: 1990, vol: 345, page: 674, stat: Journal Article,

Assembly properties of altered beta-tubulin polypeptides containing disrupted autoregulatory domains
Gu W; Cowan NJ
1989 Aug;9(8):3418-3428, Molecular & cellular biology
— id: 10532, year: 1989, vol: 9, page: 3418, stat: Journal Article,

Organization of microtubules in dendrites and axons is determined by a short hydrophobic zipper in microtubule-associated proteins MAP2 and tau
Lewis SA; Ivanov IE; Lee GH; Cowan NJ
1989 Nov 30;342(6249):498-505, Nature
— id: 10427, year: 1989, vol: 342, page: 498, stat: Journal Article,

The microtubule binding domain of microtubule-associated protein MAP1B contains a repeated sequence motif unrelated to that of MAP2 and tau
Noble M; Lewis SA; Cowan NJ
1989 Dec;109(6 Pt 2):3367-3376, Journal of cell biology
— id: 10424, year: 1989, vol: 109, page: 3367, stat: Journal Article,

Nerve growth factor regulates both the phosphorylation and steady-state levels of microtubule-associated protein 1.2 (MAP1.2)
Aletta JM; Lewis SA; Cowan NJ; Greene LA
1988 May;106(5):1573-1581, Journal of cell biology
— id: 11102, year: 1988, vol: 106, page: 1573, stat: Journal Article,

Differential distribution of beta-tubulin isotypes in cerebellum
Burgoyne RD; Cambray-Deakin MA; Lewis SA; Sarkar S; Cowan NJ
1988 Aug;7(8):2311-2319, EMBO journal
— id: 17140, year: 1988, vol: 7, page: 2311, stat: Journal Article,

TUBULIN ISOTYPES AND THEIR INTERACTION WITH MICROTUBULE ASSOCIATED PROTEINS
Cowan, NJ; Lewis, SA; Wei, G; Burgoyne, RD
1988 Sep;145(2-3):106-111, Protoplasma
— id: 31591, year: 1988, vol: 145, page: 106, stat: Journal Article,

Generation of antisera that discriminate among mammalian alpha-tubulins: introduction of specialized isotypes into cultured cells results in their coassembly without disruption of normal microtubule function
Gu W; Lewis SA; Cowan NJ
1988 Jun;106(6):2011-2022, Journal of cell biology
— id: 11078, year: 1988, vol: 106, page: 2011, stat: Journal Article,

The primary structure and heterogeneity of tau protein from mouse brain
Lee, G; Cowan, N; Kirschner, M
1988 Jan;239(4837):285-288, Science
— id: 163416, year: 1988, vol: 239, page: 285, stat: Journal Article,

THE PRIMARY STRUCTURE AND HETEROGENEITY OF TAU-PROTEIN FROM MOUSE-BRAIN
LEE, G; COWAN, N; KIRSCHNER, M
1988 JAN 15 ;239(4837):285-288, Science
— id: 41864, year: 1988, vol: 239, page: 285, stat: Journal Article,

Complex regulation and functional versatility of mammalian alpha- and beta-tubulin isotypes during the differentiation of testis and muscle cells
Lewis SA; Cowan NJ
1988 Jun;106(6):2023-2033, Journal of cell biology
— id: 11077, year: 1988, vol: 106, page: 2023, stat: Journal Article,

Microtubule-associated protein MAP2 shares a microtubule binding motif with tau protein
Lewis SA; Wang DH; Cowan NJ
1988 Nov 11;242(4880):936-939, Science
— id: 10886, year: 1988, vol: 242, page: 936, stat: Journal Article,

Complete sequence of a cDNA encoding mouse MAP2
Wang D; Lewis SA; Cowan NJ
1988 Dec 9;16(23):11369-11370, Nucleic acids research
— id: 10862, year: 1988, vol: 16, page: 11369, stat: Journal Article,

FUNCTION AND REGULATION OF EXPRESSION OF THE GENES ENCODING NEUROFILAMENT PROTEIN AND THE GLIAL FIBRILLARY ACIDIC PROTEIN
Cowan, NJ; Levy, E; Sarkan, S; Gordon, J; Lewis, S
1987 May 1;46(6):2145-2145, Federation proceedings (Federation of American Societies for Experimental Biology)
— id: 31361, year: 1987, vol: 46, page: 2145, stat: Journal Article,

Neurofilament gene expression: a major determinant of axonal caliber
Hoffman PN; Cleveland DW; Griffin JW; Landes PW; Cowan NJ; Price DL
1987 May;84(10):3472-3476, Proceedings of the National Academy of Sciences of the United States of America
— id: 17143, year: 1987, vol: 84, page: 3472, stat: Journal Article,

Structure and evolutionary origin of the gene encoding mouse NF-M, the middle-molecular-mass neurofilament protein
Levy E; Liem RK; D'Eustachio P; Cowan NJ
1987 Jul 1;166(1):71-77, European journal of biochemistry
— id: 17141, year: 1987, vol: 166, page: 71, stat: Journal Article,

Free intermingling of mammalian beta-tubulin isotypes among functionally distinct microtubules
Lewis SA; Gu W; Cowan NJ
1987 May 22;49(4):539-548, Cell
— id: 17142, year: 1987, vol: 49, page: 539, stat: Journal Article,

Anomalous placement of introns in a member of the intermediate filament multigene family: an evolutionary conundrum
Lewis SA; Cowan NJ
1986 May;6(5):1529-1534, Molecular & cellular biology
— id: 17148, year: 1986, vol: 6, page: 1529, stat: Journal Article,

Tubulin pseudogenes as markers for hominoid divergence
Lewis SA; Cowan NJ
1986 Feb 20;187(4):623-626, Journal of molecular biology
— id: 17149, year: 1986, vol: 187, page: 623, stat: Journal Article,

A cloned cDNA encoding MAP1 detects a single copy gene in mouse and a brain-abundant RNA whose level decreases during development
Lewis SA; Sherline P; Cowan NJ
1986 Jun;102(6):2106-2114, Journal of cell biology
— id: 17146, year: 1986, vol: 102, page: 2106, stat: Journal Article,

Brain-specific expression of MAP2 detected using a cloned cDNA probe
Lewis SA; Villasante A; Sherline P; Cowan NJ
1986 Jun;102(6):2098-2105, Journal of cell biology
— id: 17147, year: 1986, vol: 102, page: 2098, stat: Journal Article,

Six mouse alpha-tubulin mRNAs encode five distinct isotypes: testis-specific expression of two sister genes
Villasante A; Wang D; Dobner P; Dolph P; Lewis SA; Cowan NJ
1986 Jul;6(7):2409-2419, Molecular & cellular biology
— id: 17145, year: 1986, vol: 6, page: 2409, stat: Journal Article,

The mammalian beta-tubulin repertoire: hematopoietic expression of a novel, heterologous beta-tubulin isotype
Wang D; Villasante A; Lewis SA; Cowan NJ
1986 Nov;103(5):1903-1910, Journal of cell biology
— id: 17144, year: 1986, vol: 103, page: 1903, stat: Journal Article,

Structure of the mouse glial fibrillary acidic protein gene: implications for the evolution of the intermediate filament multigene family
Balcarek JM; Cowan NJ
1985 Aug 12;13(15):5527-5543, Nucleic acids research
— id: 17152, year: 1985, vol: 13, page: 5527, stat: Journal Article,

Structural implications of a cDNA clone encoding mouse glial fibrillary acidic protein
Cowan NJ; Lewis SA; Balcarek JM; Krek V; Shelanski M
1985 ;455(1):575-582, Annals of the New York Academy of Sciences
— id: 17156, year: 1985, vol: 455, page: 575, stat: Journal Article,

THE PHONOLOGICAL AND METAPHONOLOGICAL REPRESENTATION OF SPEECH - EVIDENCE FROM FLUENT BACKWARD TALKERS
COWAN, N; BRAINE, MDS; LEAVITT, LA
1985 JAN 20 ;24(6):679-698, Journal of memory & language
— id: 98566, year: 1985, vol: 24, page: 679, stat: Journal Article,

Structural features and restricted expression of a human alpha-tubulin gene
Hall JL; Cowan NJ
1985 Jan 11;13(1):207-223, Nucleic acids research
— id: 17155, year: 1985, vol: 13, page: 207, stat: Journal Article,

Genetics, evolution, and expression of the 68,000-mol-wt neurofilament protein: isolation of a cloned cDNA probe
Lewis SA; Cowan NJ
1985 Mar;100(3):843-850, Journal of cell biology
— id: 17154, year: 1985, vol: 100, page: 843, stat: Journal Article,

Temporal expression of mouse glial fibrillary acidic protein mRNA studied by a rapid in situ hybridization procedure
Lewis SA; Cowan NJ
1985 Sep;45(3):913-919, Journal of neurochemistry
— id: 17151, year: 1985, vol: 45, page: 913, stat: Journal Article,

Three expressed sequences within the human beta-tubulin multigene family each define a distinct isotype
Lewis SA; Gilmartin ME; Hall JL; Cowan NJ
1985 Mar 5;182(1):11-20, Journal of molecular biology
— id: 17153, year: 1985, vol: 182, page: 11, stat: Journal Article,

Five mouse tubulin isotypes and their regulated expression during development
Lewis SA; Lee MG; Cowan NJ
1985 Sep;101(3):852-861, Journal of cell biology
— id: 17150, year: 1985, vol: 101, page: 852, stat: Journal Article,

Tubulin genes and the diversity of microtubule function
Cowan NJ
1984 ;1(9):36-60, Oxford surveys on eukaryotic genes
— id: 17159, year: 1984, vol: 1, page: 36, stat: Journal Article,

SALIENT CHILDHOOD MEMORIES
COWAN, N; DAVIDSON, G
1984 JAN 20 ;145(1):101-107, Journal of genetic psychology
— id: 98589, year: 1984, vol: 145, page: 101, stat: Journal Article,

Sequence of an expressed human beta-tubulin gene containing ten Alu family members
Lee MG; Loomis C; Cowan NJ
1984 Jul 25;12(14):5823-5836, Nucleic acids research
— id: 17157, year: 1984, vol: 12, page: 5823, stat: Journal Article,

Sequence of a cDNA clone encoding mouse glial fibrillary acidic protein: structural conservation of intermediate filaments
Lewis SA; Balcarek JM; Krek V; Shelanski M; Cowan NJ
1984 May;81(9):2743-2746, Proceedings of the National Academy of Sciences of the United States of America
— id: 17158, year: 1984, vol: 81, page: 2743, stat: Journal Article,

Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions
Cowan NJ; Dobner PR; Fuchs EV; Cleveland DW
1983 Oct;3(10):1738-1745, Molecular & cellular biology
— id: 17160, year: 1983, vol: 3, page: 1738, stat: Journal Article,

Tubulin isotypes and the multigene tubulin families
Cowan NJ; Dudley L
1983 ;85(5):147-173, International review of cytology
— id: 17163, year: 1983, vol: 85, page: 147, stat: Journal Article,

Identification of two human beta-tubulin isotypes
Hall JL; Dudley L; Dobner PR; Lewis SA; Cowan NJ
1983 May;3(5):854-862, Molecular & cellular biology
— id: 17162, year: 1983, vol: 3, page: 854, stat: Journal Article,

Evolutionary history of a multigene family: an expressed human beta-tubulin gene and three processed pseudogenes
Lee MG; Lewis SA; Wilde CD; Cowan NJ
1983 Jun;33(2):477-487, Cell
— id: 17161, year: 1983, vol: 33, page: 477, stat: Journal Article,

Structure of two human alpha-tubulin genes
Wilde CD; Chow LT; Wefald FC; Cowan NJ
1982 Jan;79(1):96-100, Proceedings of the National Academy of Sciences of the United States of America
— id: 17167, year: 1982, vol: 79, page: 96, stat: Journal Article,

Diverse mechanisms in the generation of human beta-tubulin pseudogenes
Wilde CD; Crowther CE; Cowan NJ
1982 Aug 6;217(4559):549-549, Science
— id: 17164, year: 1982, vol: 217, page: 549, stat: Journal Article,

Isolation of a multigene family containing human alpha-tubulin sequences
Wilde CD; Crowther CE; Cowan NJ
1982 Mar 15;155(4):533-538, Journal of molecular biology
— id: 17166, year: 1982, vol: 155, page: 533, stat: Journal Article,

Evidence that a human beta-tubulin pseudogene is derived from its corresponding mRNA
Wilde CD; Crowther CE; Cripe TP; Gwo-Shu Lee M; Cowan NJ
1982 May 6;297(5861):83-84, Nature
— id: 17165, year: 1982, vol: 297, page: 83, stat: Journal Article,

Structural variation among human beta-tubulin genes
Cowan NJ; Wilde CD; Chow LT; Wefald FC
1981 Aug;78(8):4877-4881, Proceedings of the National Academy of Sciences of the United States of America
— id: 17168, year: 1981, vol: 78, page: 4877, stat: Journal Article,

Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes
Cleveland DW; Lopata MA; MacDonald RJ; Cowan NJ; Rutter WJ; Kirschner MW
1980 May;20(1):95-105, Cell
— id: 17169, year: 1980, vol: 20, page: 95, stat: Journal Article,

Isolation of separate mRNAs for alpha- and beta-tubulin and characterization of the corresponding in vitro translation products
Cleveland DW; Kirschner MW; Cowan NJ
1978 Nov;15(3):1021-1031, Cell
— id: 17170, year: 1978, vol: 15, page: 1021, stat: Journal Article,

Expression of antibody genes in tissue culture: structural mutants and hybrid cells
Milstein C; Adetugbo K; Cowan NJ; Kohler G; Secher DS
1978 May;15(48):321-330, National Cancer Institute monograph
— id: 17171, year: 1978, vol: 15, page: 321, stat: Journal Article,

Somatic cell genetics of antibody-secreting cells: studies of clonal diversification and analysis by cell fusion
Milstein C; Adetugbo K; Cowan NJ; Kohler G; Secher DS; Wilde CD
1977 ;41 Pt 2(48):793-803, Cold Spring Harbor symposia on quantitative biology
— id: 17172, year: 1977, vol: 41 Pt 2, page: 793, stat: Journal Article,

Purification and sequence analysis of the mRNA coding for an immunoglobulin heavy chain
Cowan NJ; Secher DS; Milstein C
1976 Jan 15;61(2):353-368, European journal of biochemistry
— id: 17173, year: 1976, vol: 61, page: 353, stat: Journal Article,

Stability of cytoplasmic ribonucleic acid in a mouse myeloma: estimation of the half-life of the messenger RNA coding for an immunoglobulin light chain
Cowan NJ; Milstein C
1974 Feb 5;82(4):469-481, Journal of molecular biology
— id: 17175, year: 1974, vol: 82, page: 469, stat: Journal Article,

Intracellular immunoglobulin chain synthesis in non-secreting variants of a mouse myeloma: detection of inactive light-chain messenger RNA
Cowan NJ; Secher DS; Milstein C
1974 Dec 25;90(4):691-701, Journal of molecular biology
— id: 17174, year: 1974, vol: 90, page: 691, stat: Journal Article,

Purification and sequence of messenger RNA for immunoglobulin light chains
Brownlee GG; Cartwright EM; Cowan NJ; Jarvis JM; Milstein C
1973 Aug 22;244(138):236-240, Nature: new biology
— id: 17176, year: 1973, vol: 244, page: 236, stat: Journal Article,

The translation in vitro of mRNA for immunoglobulin heavy chains
Cowan NJ; Milstein C
1973 Jul 2;36(1):1-7, European journal of biochemistry
— id: 17177, year: 1973, vol: 36, page: 1, stat: Journal Article,

The secretion of a sialic acid-free immunoglobulin
Cowan NJ; Secher DS; Cotton RG; Milstein C
1973 Mar 15;30(3):343-346, FEBS letters
— id: 17178, year: 1973, vol: 30, page: 343, stat: Journal Article,

Automatic monitoring of biochemical parameters in tissue culture. Studies on synchronously growing mouse myeloma cells
Cowan NJ; Milstein C
1972 Jun;128(2):445-454, Biochemical journal
— id: 17179, year: 1972, vol: 128, page: 445, stat: Journal Article,

The sequence of addition of terminal sugars to an immunoglobulin A myeloma protein
Cowan NJ; Robinson GB
1972 Feb;126(3):751-754, Biochemical journal
— id: 17180, year: 1972, vol: 126, page: 751, stat: Journal Article,

The subcellular acquisition of carbohydrates by glycoproteins
Cowan NJ; Robinson GB
1969 Dec;115(5):57P-57P, Biochemical journal
— id: 17181, year: 1969, vol: 115, page: 57P, stat: Journal Article,