William L. Carroll

Biosketch / Results /

William L. Carroll, M.D.

Professor; Julie and Edward J. Minskoff Professor of Pediatrics; Director Perlmutter Cancer Center
Departments of Perlmutter Cancer Center (Chair), Pediatrics (Oncology Division) and Pathology
NYU Pediatric Hematology Oncology

Clinical Addresses

160 E 32ND ST
NEW YORK, NY 10016
Hours: Mon. 9 - 5; Tue. 9 - 5; Wed. 9 - 5; Thu. 9 - 5; Fri. 9 - 5
Handicap Access: yes
Phone: 212-263-8400


Additional Clinical Addresses

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Medical Specialties

Cancer, Pediatrics, Hematology, Pediatric Hematology-Oncology

Medical Expertise

Transplant Infections, Lymphoma, Leukemia, Bone Marrow Transplantation, Stem Cell Transplant, Childhood Cancers, Pediatric Hematology/Oncology, Non-Hodgkin's Lymphoma

Clinical Responsibilities

Dr. William Carroll, the Julie and Edward J. Minskoff Professor of Pediatrics, directs the NYU Cancer Institute and the Pediatric Hematology Oncology Program at NYU Medical Center. He has extensive experience in all aspects of the care of children with cancer and blood diseases. He has a particular interest in the treatment of children with leukemia and directs clinical trials in acute lymphoblastic leukemia for the Children's Oncology Group.

Insurance

AETNA HMO, AETNA INDEMNITY, AETNA MEDICARE, AETNA POS, AETNA PPO/EPO, AFFINITY, AFFINITY EXCHANGE- ESSENTIAL, Cigna HMO/POS, Cigna PPO, EBCBS EPO, EBCBS HLTHY NY, EBCBS HMO, EBCBS INDEMNITY, EBCBS MEDIBLUE, EBCBS POS, EBCBS PPO, FIDELIS CHLD HLTH, FIDELIS EXCHANGE, FIDELIS FAM HLTH, FIDELIS MEDICARE, Fidelis Medicaid, GHI CBP, HEALTHPLUS CHLD HLTH (AMERIGROUP), HEALTHPLUS FAM HLTH (AMERIGROUP), HEALTHPLUS MEDICAID (AMERIGROUP), HEALTHREPUBLIC, HIP ACCESS I, HIP ACCESS II, HIP CHLD HLTH, HIP EPO/PPO, HIP FAM HLTH, HIP HMO, HIP MEDICAID, HIP MEDICARE, HIP POS, LOCAL 1199 PPO, MAGNACARE PPO, METROPLUS CHLD HLTH, METROPLUS EXCHANGE PLANS, METROPLUS FAM HLTH, MULTIPLAN/PHCS PPO, Medicare, MetroPlus Medicaid, NY MEDICAID, NYS EMPIRE PLAN, OSCAR, OXFORD EXCHANGE, OXFORD FREEDOM, Oxford Liberty, Oxford Medicare UHC COMMUNITY & STATE PLAN, UHC EPO, UHC HMO, UHC MEDICARE, UHC POS, UHC PPO, UHC TOP TIER, UNITED EXCHANGE- COMPASS, UPN Elite

Insurance Disclaimer: Insurance listed above may not be accepted at all office locations. Please confirm prior to each visit. The information presented here may not be complete or may have changed.

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Board Certification

1984 — Ab Pediatrics - Pediatrics
1987 — Ab Pediatrics (Pediatric Hematology-Oncology)

Education

1978 — University of California, Irvine, Medical Education
1978-1982 — Children's Hospital Medical Center (Pediatrics), Residency Training
1982-1984 — Stanford University Hospital (Peds Hem/Oncology), Clinical Fellowships
1984-1987 — Stanford University Hospital (Hematology Oncology), Clinical Fellowships

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Research Summary

Our laboratory is focused on two major challenges facing children with acute lymphoblastic leukemia (ALL).

First, in spite of dramatic improvements in outcome one in four children will suffer a relapse and their prognosis is poor.

Second, the "cost" of therapy for those who are cured is high with short and long term side effects. Therefore our laboratory seeks to understand mechanisms of drug resistance and to identify pathways unique to the cancer cell that can serve as targets for more effective, less toxic therapeutic approaches.

In addition we are using genomic and proteomic approaches to predict prognosis better so that therapy can be tailored to the individual patient thereby maximizing chances for cure while minimizing side effects.

We have identified gene expression profiles that predict response to therapy and are validating these signatures in an independent cohort of children currently undergoing therapy for ALL.

In addition similar efforts using expression profiling to characterize blasts at relapse has led to the provisional identification of a number of drug resistance mechanisms in ALL.

We are now using siRNA approaches to validate the functional significance of these pathways and our long term goal is to use relevant pathways as targets for therapy.

Finally we have had a long term interest in defining cell death pathways that operate in vivo and have discovered that leukemic blasts use a variety of pathways to execute apoptosis.

We hypothesize that the route of cell death correlates with response to therapy and such pathways can be modulated to favor cancer cell death thereby maximizing the therapeutic potential of conventional agents.

Our laboratory encompasses the full spectrum of investigation involving basic "bench" research, highly translational efforts using samples from patients and clinical trials in children with ALL.

Research Interests

Childhood cancers, acute leukemia, neuroblastoma, apoptotic pathways in cancer cells, microarray analysis of childhood cancer.

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Clinical Cancer Advances 2013: Annual Report on Progress Against Cancer from the American Society of Clinical Oncology
Patel, Jyoti D; Krilov, Lada; Adams, Sylvia; Aghajanian, Carol; Basch, Ethan; Brose, Marcia S; Carroll, William L; de Lima, Marcos; Gilbert, Mark R; Kris, Mark G; Marshall, John L; Masters, Gregory A; O'Day, Steven J; Polite, Blase; Schwartz, Gary K; Sharma, Sunil; Thompson, Ian; Vogelzang, Nicholas J; Roth, Bruce J
2014 Jan;32(2):129-160, Journal of clinical oncology
— id: 811012, year: 2014, vol: 32, page: 129, stat: Journal Article,

Long-term follow-up of imatinib in pediatric Philadelphia chromosome-positive acute lymphoblastic leukemia: Children's Oncology Group Study AALL0031
Schultz, KR; Carroll, A; Heerema, NA; Bowman, WP; Aledo, A; Slayton, WB; Sather, H; Devidas, M; Zheng, HW; Davies, SM; Gaynon, PS; Trigg, M; Rutledge, R; Jorstad, D; Winick, N; Borowitz, MJ; Hunger, SP; Carroll, WL; Camitta, B
2014 ;:-, Leukemia
— id: 844412, year: 2014, vol: , page: , stat: Journal Article,

Philadelphia chromosome-negative very high-risk acute lymphoblastic leukemia in children and adolescents: results from Children's Oncology Group Study AALL0031
Schultz, KR; Devidas, M; Bowman, WP; Aledo, A; Slayton, WB; Sather, H; Zheng, HW; Davies, SM; Gaynon, PS; Trigg, M; Rutledge, R; Jorstad, D; Carroll, AJ; Heerema, N; Winick, N; Borowitz, MJ; Hunger, SP; Carroll, WL; Camitta, B
2014 ;:-, Leukemia
— id: 844462, year: 2014, vol: , page: , stat: Journal Article,

SUCCESSFUL TREATMENT OF ACUTE LYMPHOBLASTIC LEUKEMIA ( ALL) WITH FIRST ISOLATED TESTICULAR RELAPSE WITH LIMITED USE OF TESTICULAR IRRADIATION: REPORT FROM CHILDREN'S ONCOLOGY GROUP (COG) AALL02P2
Barredo, J.; Caroline, H.; Lu, X.; Marcus, R.; Winick, N.; Devidas, M.; Whitlock, J.; Ritchey, A. K.; Hunger, S. P.; Carroll, W.
2013 SEP;60 3 3:28-28, Pediatric blood & cancer
— id: 627512, year: 2013, vol: 60 3 3, page: 28, stat: Journal Article,

Evolution of the histone code in relapsed acute lymphoblastic leukemia (ALL)
Bhatla, T; Wang, J; Morrison, D; Jones, C; Raetz, E; Burke, M; Brown, P; Loh, M; Hunger, S; Carroll, W
2013 June 2013;60:S40-S40, Pediatric blood & cancer
— id: 348982, year: 2013, vol: 60, page: S40, stat: Journal Article,

Safety in numbers: hyperdiploidy and prognosis
Carroll, William L
2013 Mar;121(13):2374-2376, Blood
— id: 453382, year: 2013, vol: 121, page: 2374, stat: Journal Article,

Inhibitory receptors and phosphatases enable oncogenic tyrosine kinase signaling in B cell lineage Leukemia
Chen, Z; Shojaee, S; Geng, H; Lee, J; Buchner, M; Klemm, L; Lowell, C A; Paietta, E; Willman, C L; Carroll, W L; Melnick, A M; Jung, J U; Jumaa, H; Coligan, J E; Bolland, S; Mak, T W; Muschen, M
2013 21 Oct 2013;122(21):-, Blood
— id: 713122, year: 2013, vol: 122, page: , stat: Journal Article,

OUTCOME FOR CHILDREN WITH HYPODIPLOID ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) ON CONTEMPORARY CHILDREN'S ONCOLOGY GROUP (COG) CLINICAL TRIALS
Devidas, M.; Raetz, E. A.; Loh, M. L.; Carroll, A. J.; Hereema, N. A.; Gastier-Foster, J.; Borowitz, M. J.; Wood, B.; Larsen, E.; Maloney, K. W.; Mattano, L.; Winick, N. J.; Hunger, S. P.; Carroll, W. L.
2013 SEP;60 3 3:10-10, Pediatric blood & cancer
— id: 627532, year: 2013, vol: 60 3 3, page: 10, stat: Journal Article,

Intrachromosomal Amplification of Chromosome 21 Is Associated With Inferior Outcomes in Children With Acute Lymphoblastic Leukemia Treated in Contemporary Standard-Risk Children's Oncology Group Studies: A Report From the Children's Oncology Group
Heerema, Nyla A; Carroll, Andrew J; Devidas, Meenakshi; Loh, Mignon L; Borowitz, Michael J; Gastier-Foster, Julie M; Larsen, Eric C; Mattano, Leonard A Jr; Maloney, Kelly W; Willman, Cheryl L; Wood, Brent L; Winick, Naomi J; Carroll, William L; Hunger, Stephen P; Raetz, Elizabeth A
2013 Sep;31(27):3397-3402, Journal of clinical oncology
— id: 540832, year: 2013, vol: 31, page: 3397, stat: Journal Article,

IMPROVEMENTS IN OVERALL SURVIVAL (OS) IN CHILDREN WITH NEWLY DIAGNOSED ACUTE LYMPHOBLASTIC LEUKEMIA (ALL) ENROLLED IN CHILDREN'S ONCOLOGY GROUP (COG) TRIALS IN 2000-05 VS. 2006-09
Hunger, S.; Devidas, M.; Raetz, E.; Loh, M.; Winick, N.; Carroll, W.; Lu, X.
2013 SEP;60 3 3:10-10, Pediatric blood & cancer
— id: 627542, year: 2013, vol: 60 3 3, page: 10, stat: Journal Article,

Overcoming drug resistance in PRE-B ALL by integrin alpha6 inhibition
Ji, Gang E; Hsieh, Y -T; Geng, H; Pham, J; Willman, C L; Carroll, W; Muschen, M; De, Arcangelis A; Georges-Labouesse, E; Bonig, H; Kim, Y -M
2013 February 2013;92:S25-S26, Annals of hematology
— id: 250292, year: 2013, vol: 92, page: S25, stat: Journal Article,

Tyrosine kinome sequencing of pediatric acute lymphoblastic leukemia: a report from the Children's Oncology Group TARGET Project
Loh, Mignon L; Zhang, Jinghui; Harvey, Richard C; Roberts, Kathryn; Payne-Turner, Debbie; Kang, Huining; Wu, Gang; Chen, Xiang; Becksfort, Jared; Edmonson, Michael; Buetow, Kenneth H; Carroll, William L; Chen, I-Ming; Wood, Brent; Borowitz, Michael J; Devidas, Meenakshi; Gerhard, Daniela S; Bowman, Paul; Larsen, Eric; Winick, Naomi; Raetz, Elizabeth; Smith, Malcolm; Downing, James R; Willman, Cheryl L; Mullighan, Charles G; Hunger, Stephen P
2013 Jan;121(3):485-488, Blood
— id: 222712, year: 2013, vol: 121, page: 485, stat: Journal Article,

Screening for gene mutations: will identification of NT5C2 mutations help predict the chance of relapse in acute lymphoblastic leukemia?
Meyer, Julia A; Carroll, William L; Bhatla, Teena
2013 Jun;6(3):223-224, Expert Review of Hematology
— id: 394172, year: 2013, vol: 6, page: 223, stat: Journal Article,

Relapse-specific mutations in NT5C2 in childhood acute lymphoblastic leukemia
Meyer, Julia A; Wang, Jinhua; Hogan, Laura E; Yang, Jun J; Dandekar, Smita; Patel, Jay P; Tang, Zuojian; Zumbo, Paul; Li, Sheng; Zavadil, Jiri; Levine, Ross L; Cardozo, Timothy; Hunger, Stephen P; Raetz, Elizabeth A; Evans, William E; Morrison, Debra J; Mason, Christopher E; Carroll, William L
2013 Feb;:290-294, Nature genetics
— id: 218702, year: 2013, vol: , page: 290, stat: Journal Article,

Inherited GATA3 variants are associated with Ph-like childhood acute lymphoblastic leukemia and risk of relapse
Perez-Andreu, Virginia; Roberts, Kathryn G; Harvey, Richard C; Yang, Wenjian; Cheng, Cheng; Pei, Deqing; Xu, Heng; Gastier-Foster, Julie; E, Shuyu; Lim, Joshua Yew-Suang; Chen, I-Ming; Fan, Yiping; Devidas, Meenakshi; Borowitz, Michael J; Smith, Colton; Neale, Geoffrey; Burchard, Esteban G; Torgerson, Dara G; Klussmann, Federico Antillon; Villagran, Cesar Rolando Najera; Winick, Naomi J; Camitta, Bruce M; Raetz, Elizabeth; Wood, Brent; Yue, Feng; Carroll, William L; Larsen, Eric; Bowman, W Paul; Loh, Mignon L; Dean, Michael; Bhojwani, Deepa; Pui, Ching-Hon; Evans, William E; Relling, Mary V; Hunger, Stephen P; Willman, Cheryl L; Mullighan, Charles G; Yang, Jun J
2013 Dec;45(12):1494-1498, Nature genetics
— id: 703672, year: 2013, vol: 45, page: 1494, stat: Journal Article,

A Phase I Study of EZN-3042, a Novel Survivin Messenger Ribonucleic Acid (mRNA) Antagonist, Administered in Combination With Chemotherapy in Children With Relapsed Acute Lymphoblastic Leukemia (ALL): A Report From the Therapeutic Advances in Childhood Leukemia and Lymphoma (TACL) Consortium
Raetz, Elizabeth A; Morrison, Debra; Romanos-Sirakis, Eleny; Gaynon, Paul; Sposto, Richard; Bhojwani, Deepa; Bostrom, Bruce C; Brown, Patrick; Eckroth, Elena; Cassar, Jeannette; Malvar, Jemily; Buchbinder, Aby; Carroll, William L
2013 Oct;:?-?, Journal of pediatric hematology/oncology
— id: 703662, year: 2013, vol: , page: ?, stat: Journal Article,

SOX4 enables oncogenic survival signals in acute lymphoblastic leukemia
Ramezani-Rad, Parham; Geng, Huimin; Hurtz, Christian; Chan, Lai N; Chen, Zhengshan; Jumaa, Hassan; Melnick, Ari; Paietta, Elisabeth; Carroll, William L; Willman, Cheryl L; Lefebvre, Veronique; Muschen, Markus
2013 Jan;121(1):148-155, Blood
— id: 453402, year: 2013, vol: 121, page: 148, stat: Journal Article,

HMGA1 overexpression correlates with relapse in childhood B-lineage acute lymphoblastic leukemia
Roy, Sujayita; Di Cello, Francescopaolo; Kowalski, Jeanne; Hristov, Alexandra C; Tsai, Hua-Ling; Bhojwani, Deepa; Meyer, Julia A; Carroll, William L; Belton, Amy; Resar, Linda M S
2013 Apr;:2565-2567, Leukemia & lymphoma
— id: 378222, year: 2013, vol: , page: 2565, stat: Journal Article,

Erwinia asparaginase achieves therapeutic activity after pegaspargase allergy: a report from the Children's Oncology Group
Salzer, Wanda L; Asselin, Barbara; Supko, Jeffrey G; Devidas, Meenakshi; Kaiser, Nicole A; Plourde, Paul; Winick, Naomi J; Reaman, Gregory H; Raetz, Elizabeth; Carroll, William L; Hunger, Stephen P
2013 Jun;:223-224, Blood
— id: 453372, year: 2013, vol: , page: 223, stat: Journal Article,

BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint
Swaminathan, Srividya; Huang, Chuanxin; Geng, Huimin; Chen, Zhengshan; Harvey, Richard; Kang, Huining; Ng, Carina; Titz, Bjorn; Hurtz, Christian; Sadiyah, Mohammed Firas; Nowak, Daniel; Thoennissen, Gabriela B; Rand, Vikki; Graeber, Thomas G; Koeffler, H Phillip; Carroll, William L; Willman, Cheryl L; Hall, Andrew G; Igarashi, Kazuhiko; Melnick, Ari; Muschen, Markus
2013 Jul;:1014-1022, Nature medicine
— id: 453362, year: 2013, vol: , page: 1014, stat: Journal Article,

Novel susceptibility variants at 10p12.31-12.2 for childhood acute lymphoblastic leukemia in ethnically diverse populations
Xu, Heng; Yang, Wenjian; Perez-Andreu, Virginia; Devidas, Meenakshi; Fan, Yiping; Cheng, Cheng; Pei, Deqing; Scheet, Paul; Burchard, Esteban Gonzalez; Eng, Celeste; Huntsman, Scott; Torgerson, Dara G; Dean, Michael; Winick, Naomi J; Martin, Paul L; Camitta, Bruce M; Bowman, W Paul; Willman, Cheryl L; Carroll, William L; Mullighan, Charles G; Bhojwani, Deepa; Hunger, Stephen P; Pui, Ching-Hon; Evans, William E; Relling, Mary V; Loh, Mignon L; Yang, Jun J
2013 May;105(10):733-742, Journal of the National Cancer Institute
— id: 453392, year: 2013, vol: 105, page: 733, stat: Journal Article,

Nonadherence to oral mercaptopurine and risk of relapse in Hispanic and non-Hispanic white children with acute lymphoblastic leukemia: a report from the children's oncology group
Bhatia, Smita; Landier, Wendy; Shangguan, Muyun; Hageman, Lindsey; Schaible, Alexandra N; Carter, Andrea R; Hanby, Cara L; Leisenring, Wendy; Yasui, Yutaka; Kornegay, Nancy M; Mascarenhas, Leo; Ritchey, A Kim; Casillas, Jacqueline N; Dickens, David S; Meza, Jane; Carroll, William L; Relling, Mary V; Wong, F Lennie
2012 Jun;30(17):2094-2101, Journal of clinical oncology
— id: 453432, year: 2012, vol: 30, page: 2094, stat: Journal Article,

Epigenetic reprogramming reverses the relapse-specific gene expression signature and restores chemosensitivity in childhood B-lymphoblastic leukemia
Bhatla, Teena; Wang, Jinhua; Morrison, Debra J; Raetz, Elizabeth A; Burke, Michael J; Brown, Patrick; Carroll, William L
2012 May;119(22):5201-5210, Blood
— id: 169244, year: 2012, vol: 119, page: 5201, stat: Journal Article,

Clinical and laboratory biology of childhood acute lymphoblastic leukemia
Carroll, William L; Raetz, Elizabeth A
2012 Jan;160(1):10-18, Journal of pediatrics
— id: 146251, year: 2012, vol: 160, page: 10, stat: Journal Article,

Imatinib resistant BCR-ABL1 mutations at relapse in children with Ph(+) ALL: a Children's Oncology Group (COG) study
Chang, Bill H; Willis, Stephanie G; Stork, Linda; Hunger, Stephen P; Carroll, William L; Camitta, Bruce M; Winick, Naomi J; Druker, Brian J; Schultz, Kirk R
2012 May;157(4):507-510, British journal of haematology
— id: 166678, year: 2012, vol: 157, page: 507, stat: Journal Article,

Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group Study
Chen, I-Ming; Harvey, Richard C; Mullighan, Charles G; Gastier-Foster, Julie; Wharton, Walker; Kang, Huining; Borowitz, Michael J; Camitta, Bruce M; Carroll, Andrew J; Devidas, Meenakshi; Pullen, D Jeanette; Payne-Turner, Debbie; Tasian, Sarah K; Reshmi, Shalini; Cottrell, Catherine E; Reaman, Gregory H; Bowman, W Paul; Carroll, William L; Loh, Mignon L; Winick, Naomi J; Hunger, Stephen P; Willman, Cheryl L
2012 Apr;119(15):3512-3522, Blood
— id: 165661, year: 2012, vol: 119, page: 3512, stat: Journal Article,

Pilot Study of Nelarabine in Combination With Intensive Chemotherapy in High-Risk T-Cell Acute Lymphoblastic Leukemia: A Report From the Children's Oncology Group
Dunsmore, Kimberly P; Devidas, Meenakshi; Linda, Stephen B; Borowitz, Michael J; Winick, Naomi; Hunger, Stephen P; Carroll, William L; Camitta, Bruce M
2012 Aug;30(22):2753-2759, Journal of clinical oncology
— id: 174566, year: 2012, vol: 30, page: 2753, stat: Journal Article,

Children, Adolescents, and Young Adults With Leukemia: The Empty Half of the Glass Is Growing Reply
Hunger, Stephen P.; Lu, Xiaomin; Devidas, Meenakshi; Camitta, Bruce M.; Gaynon, Paul S.; Winick, Naomi J.; Reaman, Gregory H.; Carroll, William L.
2012 NOV 10;30(32):4038-4039, Journal of clinical oncology
— id: 185722, year: 2012, vol: 30, page: 4038, stat: Journal Article,

Children's Oncology Group's 2013 blueprint for research: acute lymphoblastic leukemia
Hunger, Stephen P; Loh, Mignon L; Whitlock, James A; Winick, Naomi J; Carroll, William L; Devidas, Meenakshi; Raetz, Elizabeth A
2012 Dec;:957-963, Pediatric blood & cancer
— id: 222702, year: 2012, vol: , page: 957, stat: Journal Article,

Improved Survival for Children and Adolescents With Acute Lymphoblastic Leukemia Between 1990 and 2005: A Report From the Children's Oncology Group
Hunger, Stephen P; Lu, Xiaomin; Devidas, Meenakshi; Camitta, Bruce M; Gaynon, Paul S; Winick, Naomi J; Reaman, Gregory H; Carroll, William L
2012 May;30(14):1663-1669, Journal of clinical oncology
— id: 169026, year: 2012, vol: 30, page: 1663, stat: Journal Article,

Gene expression profiles predictive of outcome and age in infant acute lymphoblastic leukemia: a Children's Oncology Group study
Kang, Huining; Wilson, Carla S; Harvey, Richard C; Chen, I-Ming; Murphy, Maurice H; Atlas, Susan R; Bedrick, Edward J; Devidas, Meenakshi; Carroll, Andrew J; Robinson, Blaine W; Stam, Ronald W; Valsecchi, Maria G; Pieters, Rob; Heerema, Nyla A; Hilden, Joanne M; Felix, Carolyn A; Reaman, Gregory H; Camitta, Bruce; Winick, Naomi; Carroll, William L; Dreyer, Zoann E; Hunger, Stephen P; Willman, Cheryl L
2012 Feb;119(8):1872-1881, Blood
— id: 159307, year: 2012, vol: 119, page: 1872, stat: Journal Article,

Expression Profiling for MEIS1 and HOXA9/10 Identifies an Increased Incidence of MLL Rearrangements in T-ALL: A Children's Oncology Group Study
Matlawska-Wasowska, Ksenia; Harvey, Richard C.; Chen, I-Ming; Willman, Cheryl L.; Heerema, Nyla A.; Carroll, Andrew J.; Devidas, Meenakshi; Loh, Mignon L.; Hunger, Stephen P.; Raetz, Elizabeth; Mullighan, Charles G.; Asselin, Barbara; Winick, Naomi; Carroll, William L.; Larson, Richard S.; Dunsmore, Kimberly P.; Winter, Stuart S.
2012 NOV 16;120(21):-, Blood
— id: 227442, year: 2012, vol: 120, page: , stat: Journal Article,

Endogenous knockdown of survivin improves chemotherapeutic response in ALL models
Morrison, D J; Hogan, L E; Condos, G; Bhatla, T; Germino, N; Moskowitz, N P; Lee, L; Bhojwani, D; Horton, T M; Belitskaya-Levy, I; Greenberger, L M; Horak, I D; Grupp, S A; Teachey, D T; Raetz, E A; Carroll, W L
2012 Feb;26(2):271-279, Leukemia
— id: 159342, year: 2012, vol: 26, page: 271, stat: Journal Article,

Standardizing quality breast cancer care throughout all New York university facilities
Pavlick, A C; Schnabel, F R; Tiersten, A; Volm, M; Wu, J J; Boester, C; Carroll, W L
2012 01 Dec 2012;30(34):-, Journal of clinical oncology
— id: 408932, year: 2012, vol: 30, page: , stat: Journal Article,

The Relationship of Acute Gvhd and Pre- and Post-Transplant Flow-MRD to the Incidence and Timing of Relapse in Children Undergoing Allogeneic Transplantation for High Risk ALL: Defining a Target Population and Window for Immunological Intervention to Prevent Relapse
Pulsipher, Michael A.; Langholz, Bryan; Wall, Donna A.; Schultz, Kirk R.; Bunin, Nancy; Gastier-Foster, Julie M.; Borowitz, Michael J.; Goyal, Rakesh; Gardner, Sharon; Carroll, William L.; Raetz, Elizabeth; Grupp, Stephan A.
2012 NOV 16;120(21):-, Blood
— id: 227532, year: 2012, vol: 120, page: , stat: Journal Article,

IKZF1 and 22q11.22 Deletions and PDGFRA Gains Are Associated with Poor Outcome in Down Syndrome Acute Lymphoblastic Leukemia
Rabin, Karen R.; Mason, Clinton C.; Gurusiddappa, Sivashankarappa; Leung, Hon-Chiu Eastwood; Morrison, Debra J.; Bhojwani, Deepa; Barnette, Phillip; South, Sarah T.; Miles, Rodney R.; Devidas, Meenakshi; Pession, Andrea; Basso, Giuseppe; Potter, Nicola E.; Kearney, Lyndal; Moorman, Anthony V.; Raimondi, Susana C.; Jeha, Sima; Pui, Ching-Hon; Carroll, William L.; Loh, Mignon L.; Hunger, Stephen P.; Mullighan, Charles G.; Schiffman, Joshua D.
2012 NOV 16;120(21):-, Blood
— id: 227332, year: 2012, vol: 120, page: , stat: Journal Article,

Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia
Roberts, Kathryn G; Morin, Ryan D; Zhang, Jinghui; Hirst, Martin; Zhao, Yongjun; Su, Xiaoping; Chen, Shann-Ching; Payne-Turner, Debbie; Churchman, Michelle L; Harvey, Richard C; Chen, Xiang; Kasap, Corynn; Yan, Chunhua; Becksfort, Jared; Finney, Richard P; Teachey, David T; Maude, Shannon L; Tse, Kane; Moore, Richard; Jones, Steven; Mungall, Karen; Birol, Inanc; Edmonson, Michael N; Hu, Ying; Buetow, Kenneth E; Chen, I-Ming; Carroll, William L; Wei, Lei; Ma, Jing; Kleppe, Maria; Levine, Ross L; Garcia-Manero, Guillermo; Larsen, Eric; Shah, Neil P; Devidas, Meenakshi; Reaman, Gregory; Smith, Malcolm; Paugh, Steven W; Evans, William E; Grupp, Stephan A; Jeha, Sima; Pui, Ching-Hon; Gerhard, Daniela S; Downing, James R; Willman, Cheryl L; Loh, Mignon; Hunger, Stephen P; Marra, Marco A; Mullighan, Charles G
2012 Aug;22(2):153-166, Cancer cell
— id: 453422, year: 2012, vol: 22, page: 153, stat: Journal Article,

INHIBITION OF THE WNT PATHWAY IN COMBINATION WITH TRADITIONAL CHEMOTHERAPY INCREASES CHEMOSENSITIVITY IN T- AND B- ACUTE LYMPHOBLASTIC LEUKEMIA CELL LINES
Romanos-Sirakis, Eleny; Morrison, Debra; Raetz, Elizabeth; DasGupta, Ramanuj; Carroll, William
2012 JUL;58(7):1017-1018, Pediatric blood & cancer
— id: 166838, year: 2012, vol: 58, page: 1017, stat: Journal Article,

Modifications to induction therapy decrease risk of early death in infants with acute lymphoblastic leukemia treated on Children's Oncology Group P9407
Salzer, Wanda L; Jones, Tamekia L; Devidas, Meenakshi; Hilden, Joanne M; Winick, Naomi; Hunger, Stephen; Carroll, William L; Camitta, Bruce; Dreyer, ZoAnn E
2012 Nov;59(5):834-839, Pediatric blood & cancer
— id: 453442, year: 2012, vol: 59, page: 834, stat: Journal Article,

Continuous Dose Dasatinib Is Safe and Feasible in Combination with Intensive Chemotherapy in Pediatric Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia (Ph+ ALL): Children's Oncology Group (COG) Trial AALL0622
Slayton, William B.; Schultz, Kirk R.; Jones, Tamekia; Raetz, Elizabeth; Devidas, Meenakshi; Pulsipher, Michael A.; Loh, Mignon; Chang, Bill H.; Carroll, William L.; Borowitz, Michael J.; Silverman, Lewis B.; Brown, Valerie I.; Winick, Naomi; Carroll, Andrew J.; Heerema, Nyla A.; Gastier-Foster, Julie M.; Wood, Brent L.; Mizrahy, Sherri L.; Merchant, Thomas E.; Hunger, Stephen P.
2012 NOV 16;120(21):-, Blood
— id: 227482, year: 2012, vol: 120, page: , stat: Journal Article,

OUTSTANDING EARLY RESPONSES WITH DASATINIB AND INTENSIVE CHEMOTHERAPY IN PEDIATRIC PHILADELPHIA CHROMOSOME POSITIVE ACUTE LYMPHOBLASTIC LEUKEMIA (PH plus ALL): CHILDREN'S ONCOLOGY GROUP (COG) TRIAL AALL0622
Slayton, William B.; Schultz, Kirk Raymond; Jones, Tamekia; Devidas, Meenakshi; Raetz, Elizabeth Ann; Borowitz, Michael Joseph; Chang, Bill Hoon; Silverman, Lewis Barry; Pulsipher, Michael Allen; Brown, Valerie Inez; Carroll, Andrew J.; Heerema, Nyla A.; Gastier-Foster, Julie M.; Loh, Mignon L.; Winick, Naomi Joan; Wood, Brent Lee; Carroll, William L.; Hunger, Steven P.
2012 DEC;59(6):988-988, Pediatric blood & cancer
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Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling
Wey, Shiuan; Luo, Biquan; Tseng, Chun-Chih; Ni, Min; Zhou, Hui; Fu, Yong; Bhojwani, Deepa; Carroll, William L; Lee, Amy S
2012 Jan;119(3):817-825, Blood
— id: 158678, year: 2012, vol: 119, page: 817, stat: Journal Article,

ARID5B genetic polymorphisms contribute to racial disparities in the incidence and treatment outcome of childhood acute lymphoblastic leukemia
Xu, Heng; Cheng, Cheng; Devidas, Meenakshi; Pei, Deqing; Fan, Yiping; Yang, Wenjian; Neale, Geoff; Scheet, Paul; Burchard, Esteban G; Torgerson, Dara G; Eng, Celeste; Dean, Michael; Antillon, Frederico; Winick, Naomi J; Martin, Paul L; Willman, Cheryl L; Camitta, Bruce M; Reaman, Gregory H; Carroll, William L; Loh, Mignon; Evans, William E; Pui, Ching-Hon; Hunger, Stephen P; Relling, Mary V; Yang, Jun J
2012 Mar;30(7):751-757, Journal of clinical oncology
— id: 166044, year: 2012, vol: 30, page: 751, stat: Journal Article,

Genome-wide association study identifies germline polymorphisms associated with relapse of childhood acute lymphoblastic leukemia
Yang, Jun J; Cheng, Cheng; Devidas, Meenakshi; Cao, Xueyuan; Campana, Dario; Yang, Wenjian; Fan, Yiping; Neale, Geoff; Cox, Nancy; Scheet, Paul; Borowitz, Michael J; Winick, Naomi J; Martin, Paul L; Bowman, W Paul; Camitta, Bruce; Reaman, Gregory H; Carroll, William L; Willman, Cheryl L; Hunger, Stephen P; Evans, William E; Pui, Ching-Hon; Loh, Mignon; Relling, Mary V
2012 Nov;120(20):4197-4204, Blood
— id: 453412, year: 2012, vol: 120, page: 4197, stat: Journal Article,

EPIGENETIC REPROGRAMMING ENDOWS CHEMOSENSITIVITY IN LEUKEMIA CELL LINES
Bhatla, Teena; Wang, Jinhua; Morrison, Debra; Raetz, Elizabeth; Carroll, William
2011 JUN ;56(6):900-900, Pediatric blood & cancer
— id: 129014, year: 2011, vol: 56, page: 900, stat: Journal Article,

Augmented therapy improves outcome for pediatric high risk acute lymphocytic leukemia: results of Children's Oncology Group trial P9906
Bowman, W Paul; Larsen, Eric L; Devidas, Meenakshi; Linda, Stephen B; Blach, Laurie; Carroll, Andrew J; Carroll, William L; Pullen, D Jeanette; Shuster, Jonathan; Willman, Cheryl L; Winick, Naomi; Camitta, Bruce M; Hunger, Stephen P; Borowitz, Michael J
2011 Oct;57(4):569-577, Pediatric blood & cancer
— id: 453482, year: 2011, vol: 57, page: 569, stat: Journal Article,

Postrelapse survival in childhood acute lymphoblastic leukemia is independent of initial treatment intensity: a report from the Children's Oncology Group
Freyer, David R; Devidas, Meenakshi; La, Mei; Carroll, William L; Gaynon, Paul S; Hunger, Stephen P; Seibel, Nita L
2011 Mar;117(11):3010-3015, Blood
— id: 453512, year: 2011, vol: 117, page: 3010, stat: Journal Article,

Phase 2 trial of clofarabine in combination with etoposide and cyclophosphamide in pediatric patients with refractory or relapsed acute lymphoblastic leukemia
Hijiya, Nobuko; Thomson, Blythe; Isakoff, Michael S; Silverman, Lewis B; Steinherz, Peter G; Borowitz, Michael J; Kadota, Richard; Cooper, Todd; Shen, Violet; Dahl, Gary; Thottassery, Jaideep V; Jeha, Sima; Maloney, Kelly; Paul, Jo-Anne; Barry, Elly; Carroll, William L; Gaynon, Paul S
2011 Dec;118(23):6043-6049, Blood
— id: 453452, year: 2011, vol: 118, page: 6043, stat: Journal Article,

Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies
Hogan LE; Meyer JA; Yang J; Wang J; Wong N; Yang W; Condos G; Hunger SP; Raetz E; Saffery R; Relling MV; Bhojwani D; Morrison DJ; Carroll WL
2011 Nov 10;118(19):5218-5226, Blood
— id: 137806, year: 2011, vol: 118, page: 5218, stat: Journal Article,

Genomic profiling in Down syndrome acute lymphoblastic leukemia identifies histone gene deletions associated with altered methylation profiles
Loudin, M G; Wang, J; Eastwood Leung, H-C; Gurusiddappa, S; Meyer, J; Condos, G; Morrison, D; Tsimelzon, A; Devidas, M; Heerema, N A; Carroll, A J; Plon, S E; Hunger, S P; Basso, G; Pession, A; Bhojwani, D; Carroll, W L; Rabin, K R
2011 Oct;25(10):1555-1563, Leukemia
— id: 139922, year: 2011, vol: 25, page: 1555, stat: Journal Article,

Escalating intravenous methotrexate improves event-free survival in children with standard-risk acute lymphoblastic leukemia: a report from the Children's Oncology Group
Matloub, Yousif; Bostrom, Bruce C; Hunger, Stephen P; Stork, Linda C; Angiolillo, Anne; Sather, Harland; La, Mei; Gastier-Foster, Julie M; Heerema, Nyla A; Sailer, Scott; Buckley, Patrick J; Thomson, Blythe; Cole, Catherine; Nachman, James B; Reaman, Gregory; Winick, Naomi; Carroll, William L; Devidas, Meenakshi; Gaynon, Paul S
2011 Jul;118(2):243-251, Blood
— id: 453472, year: 2011, vol: 118, page: 243, stat: Journal Article,

Biology, risk stratification, and therapy of pediatric acute leukemias: an update
Pui, Ching-Hon; Carroll, William L; Meshinchi, Soheil; Arceci, Robert J
2011 Feb;29(5):551-565, Journal of clinical oncology
— id: 453502, year: 2011, vol: 29, page: 551, stat: Journal Article,

Reinduction chemoimmunotherapy with epratuzumab in relapsed Acute Lymphoblastic Leukemia (ALL) in children, adolescents and young adults: Results from Children's Oncology Group (COG) study ADVL04P2
Raetz, E A; Cairo, M S; Borowitz, M J; Lu, X; Devidas, M; Reid, J M; Goldenberg, D M; Wegener, W A; Whitlock, J A; Adamson, P C; Hunger, S P; Carroll, W L
2011 18 Nov 2011;118(21):-, Blood
— id: 169659, year: 2011, vol: 118, page: , stat: Journal Article,

Treating persistent distress and anxiety in parents of children with cancer: an initial feasibility trial
Warner, Carrie Masia; Ludwig, Kristy; Sweeney, Corinne; Spillane, Clare; Hogan, Laura; Ryan, Julie; Carroll, William
2011 Jul-Aug;28(4):224-230, Journal of pediatric oncology nursing
— id: 134914, year: 2011, vol: 28, page: 224, stat: Journal Article,

Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia
Yang, Jun J; Cheng, Cheng; Devidas, Meenakshi; Cao, Xueyuan; Fan, Yiping; Campana, Dario; Yang, Wenjian; Neale, Geoff; Cox, Nancy J; Scheet, Paul; Borowitz, Michael J; Winick, Naomi J; Martin, Paul L; Willman, Cheryl L; Bowman, W Paul; Camitta, Bruce M; Carroll, Andrew; Reaman, Gregory H; Carroll, William L; Loh, Mignon; Hunger, Stephen P; Pui, Ching-Hon; Evans, William E; Relling, Mary V
2011 Mar;43(3):237-241, Nature genetics
— id: 453492, year: 2011, vol: 43, page: 237, stat: Journal Article,

Key pathways are frequently mutated in high-risk childhood acute lymphoblastic leukemia: a report from the Children's Oncology Group
Zhang, Jinghui; Mullighan, Charles G; Harvey, Richard C; Wu, Gang; Chen, Xiang; Edmonson, Michael; Buetow, Kenneth H; Carroll, William L; Chen, I-Ming; Devidas, Meenakshi; Gerhard, Daniela S; Loh, Mignon L; Reaman, Gregory H; Relling, Mary V; Camitta, Bruce M; Bowman, W Paul; Smith, Malcolm A; Willman, Cheryl L; Downing, James R; Hunger, Stephen P
2011 Sep;118(11):3080-3087, Blood
— id: 453462, year: 2011, vol: 118, page: 3080, stat: Journal Article,

Clinical outcome of children with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated between 1995 and 2005
Arico, Maurizio; Schrappe, Martin; Hunger, Stephen P; Carroll, William L; Conter, Valentino; Galimberti, Stefania; Manabe, Atsushi; Saha, Vaskar; Baruchel, Andre; Vettenranta, Kim; Horibe, Keizo; Benoit, Yves; Pieters, Rob; Escherich, Gabriele; Silverman, Lewis B; Pui, Ching-Hon; Valsecchi, Maria Grazia
2010 Nov;28(31):4755-4761, Journal of clinical oncology
— id: 453522, year: 2010, vol: 28, page: 4755, stat: Journal Article,

Vorinostat Reverses Relapse Specific Drug Resistance Gene Expression Signatures In Childhood Acute Lymphoblastic Leukemia (ALL)
Bhatla, Teena; Wang, Jinhua; Morrison, Debra J.; Zaky, Wafik T.; Raetz, Elizabeth A.; Carroll, William L.
2010 NOV 19 ;116(21):1493-1494, Blood
— id: 130870, year: 2010, vol: 116, page: 1493, stat: Journal Article,

Cancer in children and adolescents
Carroll, William L; Finlay, Jonathan L
Sudbury MA : Jones and Bartlett, 2010,
— id: 1826, year: 2010, vol: , page: , stat: ,

Long-term results of the children's cancer group studies for childhood acute lymphoblastic leukemia 1983-2002: a Children's Oncology Group Report
Gaynon, P S; Angiolillo, A L; Carroll, W L; Nachman, J B; Trigg, M E; Sather, H N; Hunger, S P; Devidas, M
2010 Feb;24(2):285-297, Leukemia
— id: 453582, year: 2010, vol: 24, page: 285, stat: Journal Article,

Rearrangement of CRLF2 is associated with mutation of JAK kinases, alteration of IKZF1, Hispanic/Latino ethnicity, and a poor outcome in pediatric B-progenitor acute lymphoblastic leukemia
Harvey, Richard C; Mullighan, Charles G; Chen, I-Ming; Wharton, Walker; Mikhail, Fady M; Carroll, Andrew J; Kang, Huining; Liu, Wei; Dobbin, Kevin K; Smith, Malcolm A; Carroll, William L; Devidas, Meenakshi; Bowman, W Paul; Camitta, Bruce M; Reaman, Gregory H; Hunger, Stephen P; Downing, James R; Willman, Cheryl L
2010 Jul;115(26):5312-5321, Blood
— id: 453552, year: 2010, vol: 115, page: 5312, stat: Journal Article,

Identification of novel cluster groups in pediatric high-risk B-precursor acute lymphoblastic leukemia with gene expression profiling: correlation with genome-wide DNA copy number alterations, clinical characteristics, and outcome
Harvey, Richard C; Mullighan, Charles G; Wang, Xuefei; Dobbin, Kevin K; Davidson, George S; Bedrick, Edward J; Chen, I-Ming; Atlas, Susan R; Kang, Huining; Ar, Kerem; Wilson, Carla S; Wharton, Walker; Murphy, Maurice; Devidas, Meenakshi; Carroll, Andrew J; Borowitz, Michael J; Bowman, W Paul; Downing, James R; Relling, Mary; Yang, Jun; Bhojwani, Deepa; Carroll, William L; Camitta, Bruce; Reaman, Gregory H; Smith, Malcolm; Hunger, Stephen P; Willman, Cheryl L
2010 Dec;116(23):4874-4884, Blood
— id: 453532, year: 2010, vol: 116, page: 4874, stat: Journal Article,

GENE EXPRESSION ANALYSIS REVEALS DISTINCT SIGNATURES FOR EARLY AND LATE RELAPSE IN PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)
Hogan, L; Meyer, J; Wang, JH; Morrison, D; Yang, J; Hunger, S; Willman, C; Relling, M; Raetz, E; Bhojwani, D; Carroll, W
2010 JUN ;54(6):790-791, Pediatric blood & cancer
— id: 110438, year: 2010, vol: 54, page: 790, stat: Journal Article,

Toxicity assessment of molecularly targeted drugs incorporated into multiagent chemotherapy regimens for pediatric acute lymphocytic leukemia (ALL): review from an international consensus conference
Horton, Terzah M; Sposto, Richard; Brown, Patrick; Reynolds, C Patrick; Hunger, Stephen P; Winick, Naomi J; Raetz, Elizabeth A; Carroll, William L; Arceci, Robert J; Borowitz, Michael J; Gaynon, Paul S; Gore, Lia; Jeha, Sima; Maurer, Barry J; Siegel, Stuart E; Biondi, Andrea; Kearns, Pamela R; Narendran, Aru; Silverman, Lewis B; Smith, Malcolm A; Zwaan, C Michel; Whitlock, James A
2010 Jul;54(7):872-878, Pediatric blood & cancer
— id: 222752, year: 2010, vol: 54, page: 872, stat: Journal Article,

Phase 2 Results of Clofarabine In Combination with Etoposide and Cyclophosphamide In Pediatric Patients with Refractory or Relapsed Acute Lymphoblastic Leukemia
Huiya, Nobuko; Paul, Jo Anne; Borowitz, Michael J.; Thomson, Blythe; Isakoff, Michael; Silverman, Lewis B.; Steinherz, Peter G.; Kadota, Richard; Pressey, Joseph G.; Shen, Violet; Chu, Roland; Cooper, Todd; Jeha, Sima; Razzouk, Bassem I.; Rytting, Michael E.; Barry, Elly; Carroll, William L.; Gaynon, Paul
2010 NOV 19 ;116(21):378-379, Blood
— id: 130864, year: 2010, vol: 116, page: 378, stat: Journal Article,

Gene expression classifiers for relapse-free survival and minimal residual disease improve risk classification and outcome prediction in pediatric B-precursor acute lymphoblastic leukemia
Kang, Huining; Chen, I-Ming; Wilson, Carla S; Bedrick, Edward J; Harvey, Richard C; Atlas, Susan R; Devidas, Meenakshi; Mullighan, Charles G; Wang, Xuefei; Murphy, Maurice; Ar, Kerem; Wharton, Walker; Borowitz, Michael J; Bowman, W Paul; Bhojwani, Deepa; Carroll, William L; Camitta, Bruce M; Reaman, Gregory H; Smith, Malcolm A; Downing, James R; Hunger, Stephen P; Willman, Cheryl L
2010 Feb;115(7):1394-1405, Blood
— id: 453602, year: 2010, vol: 115, page: 1394, stat: Journal Article,

Gene Expression Profiling Reveals Genes Predictive of Outcome In Infant Acute Lymphoblastic Leukemia (ALL) and Distinctive Age Related Gene Expression Profiles (< 90 Days vs > 90 Days) A Children's Oncology Group Study
Kang, Huining; Wilson, Carla S.; Harvey, Richard C.; Chen, I. Ming; Murphy, Maurice H.; Atlas, Susan R.; Bedrick, Edward J.; Devidas, Meenakshi; Carroll, Andrew J.; Robinson, Blaine W.; Heerema, Nyla A.; Hilden, Joanne M.; Dreyer, Zoann E.; Camitta, Bruce; Winick, Naomi; Carroll, William L.; Felix, Carolyn A.; Reaman, Gregory H.; Hunger, Stephen P.; William, Cheryl L.
2010 NOV 19 ;116(21):183-184, Blood
— id: 130857, year: 2010, vol: 116, page: 183, stat: Journal Article,

Early Response Characteristics and Blast Cytogenetic FEatures In 5,377 Children with Standard Risk Acute Lymphoblastic Leukemia (SR-ALL) A Children's Oncology Group (COG) Study
Maloney, Kelly W.; Loh, Mignon L.; Raetz, Elizabeth; Borowitz, Michael J.; Devidas, Meenakshi; Friedmann, Alison M.; Mattano, Leonard A.; Wood, Brent; Winick, Naomi; Hunger, Stephen; Carroll, William L.
2010 NOV 19 ;116(21):184-184, Blood
— id: 130858, year: 2010, vol: 116, page: 184, stat: Journal Article,

Down syndrome childhood acute lymphoblastic leukemia has a unique spectrum of sentinel cytogenetic lesions that influences treatment outcome: a report from the Children's Oncology Group
Maloney, Kelly W; Carroll, William L; Carroll, Andrew J; Devidas, Meenakshi; Borowitz, Michael J; Martin, Paul L; Pullen, Jeanette; Whitlock, James A; Willman, Cheryl L; Winick, Naomi J; Camitta, Bruce M; Hunger, Stephen P
2010 Aug;116(7):1045-1050, Blood
— id: 453542, year: 2010, vol: 116, page: 1045, stat: Journal Article,

Children with Down Syndrome (DS) and NCI Standard Risk (SR) Acute Lymphoblastic Leukemia (ALL) Have a Superior Five Year Event Free Survival (EFS) When Treated with Escalating Intravenous Methotrexate on the Children's Cancer Group (CCG) Study 1991
Matloub, Yousif; Bostrom, Bruce C.; Hunger, Stephen; Angiolillo, Anne; Devidas, Meenakshi; La, Mei; Heerema, Nyla A.; Winick, Naomi; Nachman, James; Sather, Harland; Carroll, William L.; Gaynon, Paul S.
2010 NOV 19 ;116(21):221-221, Blood
— id: 130860, year: 2010, vol: 116, page: 221, stat: Journal Article,

High Throughput Transcriptome Sequencing of Pediatric Relapsed Acute Lymphoblastic Leukemia (ALL) Identifies Relapse Specific Mutations and Expression
Meyer, Julia A.; Hogan, Laura E.; Wang, Jinhua; Yang, Jun J.; Patel, Jay; Levine, Ross L.; Hunger, Stephen P.; Raetz, Elizabeth; Mason, Christopher; Carroll, William L.
2010 NOV 19 ;116(21):1326-1326, Blood
— id: 130868, year: 2010, vol: 116, page: 1326, stat: Journal Article,

Biology and treatment of acute lymphoblastic leukemia
Pieters, Rob; Carroll, William L
2010 Feb;24(1):1-18, Hematology-oncology clinics of North America
— id: 453572, year: 2010, vol: 24, page: 1, stat: Journal Article,

Long-term results of the pediatric oncology group studies for childhood acute lymphoblastic leukemia 1984-2001: a report from the children's oncology group
Salzer, W L; Devidas, M; Carroll, W L; Winick, N; Pullen, J; Hunger, S P; Camitta, B A
2010 Feb;24(2):355-370, Leukemia
— id: 453592, year: 2010, vol: 24, page: 355, stat: Journal Article,

Administration of Erwinia Asparaginase (Erwinase (R)) Following Allergy to PEG-Asparaginase In Children and Young Adults with Acute Lymphoblastic Leukemia Treated on AALL07P2 Achieves Therapeutic Nadir Serum Asparaginase Activity: A Report From the Children's Oncology Group (COG)
Salzer, Wanda; Asselin, Barbara; Supko, Jeffrey; Devidas, Meenakshi; Kaiser, Nicole; Plourde, Paul V.; Winick, Naomi; Reaman, Gregory; Raetz, Elizabeth; Carroll, William L.; Hunger, Stephen
2010 NOV 19 ;116(21):882-882, Blood
— id: 134502, year: 2010, vol: 116, page: 882, stat: Journal Article,

Infant Acute Lymphoblastic Leukemias Are Pan Sensitive to Obatoclax Across molecular/Cytogenetic Subtypes, Especially MLL ENL, and gene Expression Profiles Determine Obatoclax IC50 A Report on the Children's Oncology Group (COG) P9407 Trial
Urtishak, Karen A.; Wang, Li San; Harvey, Richard; Atlas, Susan R.; Chen, I. Ming L.; Robinson, Blaine W.; Moukarzel, Lea; Cao, Kajia; Devidas, Meenakshi; Carroll, Andrew J.; Heerema, Nyla A.; Hunger, Stephen; Reaman, Gregory H.; Hilden, Joanne M.; Camitta, Bruce; Winick, Naomi; Carroll, William L.; Zhang, Alena Y.; Cory, Lori; McVeigh, Steven; Barrett, Jeffery S.; Dreyer, Zoann E.; Willman, Cheryl L.; Felix, Carolyn A.
2010 NOV 19 ;116(21):1137-1137, Blood
— id: 130866, year: 2010, vol: 116, page: 1137, stat: Journal Article,

Nelarabine May Be Safely Incorporated Into a Phase III Study for Newly Diagnosed T Lineage Acute Lymphoblastic Leukemia A Report From the Children's Oncology Group
Winter, Stuart S.; Devidas, Meenakshi; Wood, Brent; Borowitz, Michael J.; Loh, Mignon L.; Asselin, Barbara; Murphy, John; Raetz, Elizabeth; Winick, Naomi; Hunger, Stephen; Carroll, William; Dunsmore, Kimberly
2010 NOV 19 ;116(21):378-378, Blood
— id: 130863, year: 2010, vol: 116, page: 378, stat: Journal Article,

IKAROS DELETION LEADS TO CHEMOTHERAPY RESISTANCE IN PEDIATRIC ACUTE LYMPHOBLASTIC LEUKEMIA
Zaky, W; Chen, Z; Meyer, J; Bhatla, T; Yang, J; Relling, M; Yang, WJ; Wang, JH; Morrison, D; Raetz, E; Carroll, W
2010 JUN ;54(6):789-789, Pediatric blood & cancer
— id: 110437, year: 2010, vol: 54, page: 789, stat: Journal Article,

Lack of Somatic Sequence Mutations In Protein Tyrosine Kinase Genes Other Than the JAK Kinase Family In High Risk B Precursor Childhood Acute Lymphoblastic Leukemia (ALL) A Report From the Children's Oncology Group (COG) High Risk (HR) ALL TARGET Project
Zhang, Jinghui; Mullighan, Charles; Harvey, Richard; Carroll, William L.; Chen, I. Ming L.; Devidas, Meenakshi; Larsen, Eric; Edmonson, Michael; Buetow, Ken; Gerhard, Daniela S.; Loh, Mignon L.; Reaman, Gregory H.; Relling, Mary V.; Smith, Malcolm A.; Downing, James R.; Willman, Cheryl L.; Hunger, Stephen
2010 NOV 19 ;116(21):1135-1135, Blood
— id: 130865, year: 2010, vol: 116, page: 1135, stat: Journal Article,

Report On Excessive Induction Toxicity in Infants with ALL Enrolled On COG Protocol AALL0631: A Children's Oncology Group Study
Brown, P; Hilden, JM; Dreyer, ZE; Winick, NJ; Salzer, W; Raetz, E; Sung, L; Zaoutis, TE; Jones, T; Devidas, M; De Lorenzo, P; Valsecchi, MG; Pieters, R; Carroll, WL; Hunger, SP
2009 NOV 20 ;114(22):1202-1202, Blood
— id: 109995, year: 2009, vol: 114, page: 1202, stat: Journal Article,

Novel targeted drug therapies for the treatment of childhood acute leukemia
Brown, Patrick; Hunger, Stephen P; Smith, Franklin O; Carroll, William L; Reaman, Gregory H
2009 Apr;2(9):145-145, Expert Review of Hematology
— id: 453562, year: 2009, vol: 2, page: 145, stat: Journal Article,

Novel targeted drug therapies I for the treatment of childhood acute leukemia
Brown, Patrick; Hunger, Steven P.; Smith, Franklin O.; Carroll, William L.; Reaman, Gregory H.
2009 APR ;2(2):145-158, Expert Review of Hematology
— id: 115371, year: 2009, vol: 2, page: 145, stat: Journal Article,

Masked Hypodiploidy: Hypodiploid Acute Lymphoblastic Leukemia (ALL) in Children Mimicking Hyperdiploid A
Carroll, AJ; Heerema, NA; Gastier-Foster, JM; Astbury, C; Pyatt, R; Reshmi, SC; Borowitz, MJ; Devidas, M; Linda, S; Loh, ML; Raetz, EA; Wood, B; Winick, NJ; Hunger, SP; Carroll, WL
2009 NOV 20 ;114(22):632-632, Blood
— id: 109980, year: 2009, vol: 114, page: 632, stat: Journal Article,

AAML0523: A Report From the Children's Oncology Group On the Safety of Clofarabine in Combination with Cytarabine in Pediatric Patients with Relapsed Acute Leukemia
Cooper, T; Alonzo, TA; Gerbing, RB; Perentesis, J; Whitlock, JA; Raetz, E; Carroll, WL; Gamis, AS; Razzouk, BI
2009 NOV 20 ;114(22):1196-1196, Blood
— id: 109994, year: 2009, vol: 114, page: 1196, stat: Journal Article,

Amplification of AML1 Does Not Impact Early Outcome of Children with Acute Lymphoblastic Leukemia (ALL) Treated with Risk-Directed Chemotherapy: A Report From the Children's Oncology Group (COG)
Heerema, NA; Carroll, AJ; Borowitz, MJ; Devidas, M; Larson, EC; Loh, M; Mattano, LA; Maloney, K; Raetz, E; Wood, B; Winick, NJ; Hunger, SP; Carroll, WL
2009 NOV 20 ;114(22):1019-1020, Blood
— id: 109992, year: 2009, vol: 114, page: 1019, stat: Journal Article,

A multi-center phase I study of clofarabine, etoposide and cyclophosphamide in combination in pediatric patients with refractory or relapsed acute leukemia
Hijiya, N; Gaynon, P; Barry, E; Silverman, L; Thomson, B; Chu, R; Cooper, T; Kadota, R; Rytting, M; Steinherz, P; Shen, V; Jeha, S; Abichandani, R; Carroll, W L
2009 Dec;23(12):2259-2264, Leukemia
— id: 453632, year: 2009, vol: 23, page: 2259, stat: Journal Article,

Up-Regulation of Genes Involved in Folate Metabolism Characterize Late but Not Early Relapse in Childhood Acute Lymphoblastic Leukemia
Hogan, L; Bhojwani, D; Wang, JH; Morrison, D; Yang, JJ; Zhang, YT; Zavadil, J; Condos, G; Hunger, SP; Willman, CL; Relling, MV; Raetz, E; Carroll, WL
2009 NOV 20 ;114(22):689-690, Blood
— id: 109987, year: 2009, vol: 114, page: 689, stat: Journal Article,

(PLATFORM 302C) ANTISENSE TECHNOLOGY TARGETING AN ANTI-APOPTOTIC GENE IMPROVES LEUKEMIC CELL DEATH IN ALL CELL LINES AND MICE
Hogan, LE; Teachey, DT; Germino, N; Moskowitz, N; Condos, G; Belitskaya-Levy, H; Wang, JH; Bhojwani, D; Horton, TM; Sapra, P; Horak, I; Raetz, E; Grupp, SA; Carroll, W; Morrison, D
2009 JUN ;52(6):695-695, Pediatric blood & cancer
— id: 97794, year: 2009, vol: 52, page: 695, stat: Journal Article,

Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia
Mullighan, Charles G; Collins-Underwood, J Racquel; Phillips, Letha A A; Loudin, Michael G; Liu, Wei; Zhang, Jinghui; Ma, Jing; Coustan-Smith, Elaine; Harvey, Richard C; Willman, Cheryl L; Mikhail, Fady M; Meyer, Julia; Carroll, Andrew J; Williams, Richard T; Cheng, Jinjun; Heerema, Nyla A; Basso, Giuseppe; Pession, Andrea; Pui, Ching-Hon; Raimondi, Susana C; Hunger, Stephen P; Downing, James R; Carroll, William L; Rabin, Karen R
2009 Nov;41(11):1243-1246, Nature genetics
— id: 453612, year: 2009, vol: 41, page: 1243, stat: Journal Article,

Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia
Mullighan, Charles G; Su, Xiaoping; Zhang, Jinghui; Radtke, Ina; Phillips, Letha A A; Miller, Christopher B; Ma, Jing; Liu, Wei; Cheng, Cheng; Schulman, Brenda A; Harvey, Richard C; Chen, I-Ming; Clifford, Robert J; Carroll, William L; Reaman, Gregory; Bowman, W Paul; Devidas, Meenakshi; Gerhard, Daniela S; Yang, Wenjian; Relling, Mary V; Shurtleff, Sheila A; Campana, Dario; Borowitz, Michael J; Pui, Ching-Hon; Smith, Malcolm; Hunger, Stephen P; Willman, Cheryl L; Downing, James R
2009 Jan 29;360(5):470-480, New England journal of medicine
— id: 96132, year: 2009, vol: 360, page: 470, stat: Journal Article,

JAK mutations in high-risk childhood acute lymphoblastic leukemia
Mullighan, Charles G; Zhang, Jinghui; Harvey, Richard C; Collins-Underwood, J Racquel; Schulman, Brenda A; Phillips, Letha A; Tasian, Sarah K; Loh, Mignon L; Su, Xiaoping; Liu, Wei; Devidas, Meenakshi; Atlas, Susan R; Chen, I-Ming; Clifford, Robert J; Gerhard, Daniela S; Carroll, William L; Reaman, Gregory H; Smith, Malcolm; Downing, James R; Hunger, Stephen P; Willman, Cheryl L
2009 Jun;106(23):9414-9418, Proceedings of the National Academy of Sciences of the United States of America
— id: 453652, year: 2009, vol: 106, page: 9414, stat: Journal Article,

Gene Expression Profiling in Down Syndrome Acute Lymphoblastic Leukemia Identifies Distinct Profiles Associated with CRLF2 Expression Status
Rabin, KR; Wang, JH; Meyer, J; Loudin, MG; Bhojwani, D; Morrison, D; Heerema, NA; Carroll, AJ; Pession, A; Basso, G; Mullighan, CG; Hunger, SP; Carroll, WL
2009 NOV 20 ;114(22):943-943, Blood
— id: 109990, year: 2009, vol: 114, page: 943, stat: Journal Article,

Improved early event-free survival with imatinib in Philadelphia chromosome-positive acute lymphoblastic leukemia: a children's oncology group study
Schultz, Kirk R; Bowman, W Paul; Aledo, Alexander; Slayton, William B; Sather, Harland; Devidas, Meenakshi; Wang, Chenguang; Davies, Stella M; Gaynon, Paul S; Trigg, Michael; Rutledge, Robert; Burden, Laura; Jorstad, Dean; Carroll, Andrew; Heerema, Nyla A; Winick, Naomi; Borowitz, Michael J; Hunger, Stephen P; Carroll, William L; Camitta, Bruce
2009 Nov;27(31):5175-5181, Journal of clinical oncology
— id: 453622, year: 2009, vol: 27, page: 5175, stat: Journal Article,

Germline genomic variants associated with childhood acute lymphoblastic leukemia
Trevino, Lisa R; Yang, Wenjian; French, Deborah; Hunger, Stephen P; Carroll, William L; Devidas, Meenakshi; Willman, Cheryl; Neale, Geoffrey; Downing, James; Raimondi, Susana C; Pui, Ching-Hon; Evans, William E; Relling, Mary V
2009 Sep;41(9):1001-1005, Nature genetics
— id: 453642, year: 2009, vol: 41, page: 1001, stat: Journal Article,

Patients with Early T-Cell Precursor (ETP) Acute Lymphoblastic Leukemia (ALL) Have High Levels of Minimal Residual Disease (MRD) at the End of induction-A Children's Oncology Group (COG) Study
Wood, B; Winter, S; Dunsmore, K; Raetz, E; Borowitz, MJ; Devidas, M; Winick, NJ; Carroll, WL; Hunger, SP; Loh, ML
2009 NOV 20 ;114(22):9-10, Blood
— id: 109968, year: 2009, vol: 114, page: 9, stat: Journal Article,

Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia
Yang, Jun J; Cheng, Cheng; Yang, Wenjian; Pei, Deqing; Cao, Xueyuan; Fan, Yiping; Pounds, Stanley B; Neale, Geoffrey; Trevino, Lisa R; French, Deborah; Campana, Dario; Downing, James R; Evans, William E; Pui, Ching-Hon; Devidas, Meenakshi; Bowman, W P; Camitta, Bruce M; Willman, Cheryl L; Davies, Stella M; Borowitz, Michael J; Carroll, William L; Hunger, Stephen P; Relling, Mary V
2009 Jan 28;301(4):393-403, JAMA
— id: 96131, year: 2009, vol: 301, page: 393, stat: Journal Article,

Clinical Outcome of 640 Children with Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia Treated Between 1995 and 2005
Arica, M; Schrappe, M; Hunger, S; Carroll, WL; Conter, V; Di Lorenzo, P; Manabe, A; Saba, V; Baruchel, A; Vettenranta, K; Tsuchida, M; Benoit, Y; Pieters, R; Escherich, G; Silverman, LB; Pui, CH; Valsecchi, MG
2008 NOV 16 ;112(11):213-214, Blood
— id: 93285, year: 2008, vol: 112, page: 213, stat: Journal Article,

Evolution of Gene Expression Signatures in Relapsed Childhood Acute Lymphoblastic Leukemia Differs Based on Timing of Relapse
Bhojwani, D; Wang, J; Yang, JJ; Morrison, D; Devidas, M; Raetz, E; Hunger, SP; Relling, MV; Carroll, WL
2008 NOV 16 ;112(11):1149-1149, Blood
— id: 93293, year: 2008, vol: 112, page: 1149, stat: Journal Article,

Gene expression signatures predictive of early response and outcome in high-risk childhood acute lymphoblastic leukemia: a Children's Oncology Group Study on behalf of the Dutch Childhood Oncology Group and the German Cooperative Study Group for Childhood Acute Lymphoblastic Leukemia
Bhojwani, Deepa; Kang, Huining; Menezes, Renee X; Yang, Wenjian; Sather, Harland; Moskowitz, Naomi P; Min, Dong-Joon; Potter, Jeffrey W; Harvey, Richard; Hunger, Stephen P; Seibel, Nita; Raetz, Elizabeth A; Pieters, Rob; Horstmann, Martin A; Relling, Mary V; den Boer, Monique L; Willman, Cheryl L; Carroll, William L
2008 Sep 20;26(27):4376-4384, Journal of clinical oncology
— id: 87810, year: 2008, vol: 26, page: 4376, stat: Journal Article,

Clinical significance of minimal residual disease in childhood acute lymphoblastic leukemia and its relationship to other prognostic factors: a Children's Oncology Group study
Borowitz, Michael J; Devidas, Meenakshi; Hunger, Stephen P; Bowman, W Paul; Carroll, Andrew J; Carroll, William L; Linda, Stephen; Martin, Paul L; Pullen, D Jeanette; Viswanatha, David; Willman, Cheryl L; Winick, Naomi; Camitta, Bruce M
2008 Jun 15;111(12):5477-5485, Blood
— id: 96133, year: 2008, vol: 111, page: 5477, stat: Journal Article,

"When can I go home?"-seeking ways to lower the burden on patients and families
Carroll, William L; Raetz, Elizabeth A
2008 Sep;51(3):318-319, Pediatric blood & cancer
— id: 80817, year: 2008, vol: 51, page: 318, stat: Journal Article,

Risk-adapted therapy for children with acute lymphoblastic leukemia (ALL): The children's oncology group (COG) approach
Carroll, WL; Hunger, SP; Borowitz, MJ; Bhojwani, D; Willman, CL; Devidas, M; Schultz, K; Loh, ML; Raetz, EA
2008 FEB ;87(1):S42-S47, Annals of hematology
— id: 87145, year: 2008, vol: 87, page: S42, stat: Journal Article,

Outcomes after HLA-matched sibling transplantation or chemotherapy in children with acute lymphoblastic leukemia in a second remission after an isolated central nervous system relapse: a collaborative study of the Children's Oncology Group and the Center for International Blood and Marrow Transplant Research
Eapen, M; Zhang, M-J; Devidas, M; Raetz, E; Barredo, J C; Ritchey, A K; Godder, K; Grupp, S; Lewis, V A; Malloy, K; Carroll, W L; Davies, S M; Camitta, B M
2008 Feb;22(2):281-286, Leukemia
— id: 135322, year: 2008, vol: 22, page: 281, stat: Journal Article,

Increased Incidence of Osteonecrosis (ON) with a Dexamethasone (DEX) Induction for High Risk Acute Lymphoblastic Leukemia (HR-ALL): A Report from the Children's Oncology Group (COG)
Mattano, LA; Nachman, JB; Devidas, M; Winick, N; Raetz, E; Carroll, WL; Whitlock, JA; Hunger, SP; Larsen, EC
2008 NOV 16 ;112(11):333-334, Blood
— id: 93286, year: 2008, vol: 112, page: 333, stat: Journal Article,

Factors influencing survival after relapse from acute lymphoblastic leukemia: a Children's Oncology Group study
Nguyen, K; Devidas, M; Cheng, S-C; La, M; Raetz, E A; Carroll, W L; Winick, N J; Hunger, S P; Gaynon, P S; Loh, M L
2008 Dec;22(12):2142-2150, Leukemia
— id: 453662, year: 2008, vol: 22, page: 2142, stat: Journal Article,

Biology and treatment of acute lymphoblastic leukemia
Pieters, Rob; Carroll, William L
2008 Feb;55(1):5477-5485, Pediatric clinics of North America
— id: 96134, year: 2008, vol: 55, page: 5477, stat: Journal Article,

Gene Expression Profiling Differentiates Childhood Acute Lymphoblastic Leukemia in Down Syndrome Versus Non-Down Syndrome Patients
Rabin, KR; Wang, JH; Tsimelzon, A; Morrison, D; Gaikwad, AS; Hogan, L; Rye, CL; Hilsenbeck, SG; Devidas, M; Heerema, NA; Carroll, AJ; Basso, G; Carroll, WL; Pession, A; Bhojwani, D
2008 NOV 16 ;112(11):438-439, Blood
— id: 93287, year: 2008, vol: 112, page: 438, stat: Journal Article,

Reinduction platform for children with first marrow relapse in acute lymphoblastic lymphoma
Raetz, Elizabeth A; Borowitz, Michael J; Devidas, Meenakshi; Linda, Stephen B; Hunger, Stephen P; Winick, Naomi J; Camitta, Bruce M; Gaynon, Paul S; Carroll, William L
2008 Aug 20;26(24):3971-3978, Journal of clinical oncology
— id: 82923, year: 2008, vol: 26, page: 3971, stat: Journal Article,

Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children's Oncology Group Pilot Study
Raetz, Elizabeth A; Cairo, Mitchell S; Borowitz, Michael J; Blaney, Susan M; Krailo, Mark D; Leil, Tarek A; Reid, Joel M; Goldenberg, David M; Wegener, William A; Carroll, William L; Adamson, Peter C
2008 Aug 1;26(22):3756-3762, Journal of clinical oncology
— id: 80821, year: 2008, vol: 26, page: 3756, stat: Journal Article,

Genome-wide copy number profiling reveals molecular evolution from diagnosis to relapse in childhood acute lymphoblastic leukemia
Yang, Jun J; Bhojwani, Deepa; Yang, Wenjian; Cai, Xiangjun; Stocco, Gabriele; Crews, Kristine; Wang, Jinhua; Morrison, Debra; Devidas, Meenakshi; Hunger, Stephen P; Willman, Cheryl L; Raetz, Elizabeth A; Pui, Ching-Hon; Evans, William E; Relling, Mary V; Carroll, William L
2008 Nov 15;112(10):4178-4183, Blood
— id: 86639, year: 2008, vol: 112, page: 4178, stat: Journal Article,

End points to establish the efficacy of new agents in the treatment of acute leukemia
Appelbaum, Frederick R; Rosenblum, Daniel; Arceci, Robert J; Carroll, William L; Breitfeld, Philip P; Forman, Stephen J; Larson, Richard A; Lee, Stephanie J; Murphy, Sharon B; O'Brien, Susan; Radich, Jerald; Scher, Nancy S; Smith, Franklin O; Stone, Richard M; Tallman, Martin S
2007 Mar 1;109(5):1810-1816, Blood
— id: 74584, year: 2007, vol: 109, page: 1810, stat: Journal Article,

Potential of gene expression profiling in the management of childhood acute lymphoblastic leukemia
Bhojwani, Deepa; Moskowitz, Naomi; Raetz, Elizabeth A; Carroll, William L
2007 ;9(3):149-156, Paediatric drugs
— id: 73237, year: 2007, vol: 9, page: 149, stat: Journal Article,

Obesity and outcome in pediatric acute lymphoblastic leukemia
Butturini, Anna M; Dorey, Frederick J; Lange, Beverly J; Henry, David W; Gaynon, Paul S; Fu, Cecilia; Franklin, Janet; Siegel, Stuart E; Seibel, Nita L; Rogers, Paul C; Sather, Harland; Trigg, Michael; Bleyer, W Archie; Carroll, William L
2007 May 20;25(15):2063-2069, Journal of clinical oncology
— id: 74582, year: 2007, vol: 25, page: 2063, stat: Journal Article,

Risk- and response-based classification of childhood B-precursor acute lymphoblastic leukemia: a combined analysis of prognostic markers from the Pediatric Oncology Group (POG) and Children's Cancer Group (CCG)
Schultz, Kirk R; Pullen, D Jeanette; Sather, Harland N; Shuster, Jonathan J; Devidas, Meenakshi; Borowitz, Michael J; Carroll, Andrew J; Heerema, Nyla A; Rubnitz, Jeffrey E; Loh, Mignon L; Raetz, Elizabeth A; Winick, Naomi J; Hunger, Stephen P; Carroll, William L; Gaynon, Paul S; Camitta, Bruce M
2007 Feb 1;109(3):926-935, Blood
— id: 74586, year: 2007, vol: 109, page: 926, stat: Journal Article,

Genetic studies of a cluster of acute lymphoblastic leukemia cases in Churchill County, Nevada
Steinberg, Karen K; Relling, Mary V; Gallagher, Margaret L; Greene, Christopher N; Rubin, Carol S; French, Deborah; Holmes, Adrianne K; Carroll, William L; Koontz, Deborah A; Sampson, Eric J; Satten, Glen A
2007 Jan;115(1):158-164, Environmental health perspectives
— id: 74583, year: 2007, vol: 115, page: 158, stat: Journal Article,

Children with t(12;21)/TEL-AML1-positive acute lymphoblastic leukemia exhibit a distinct germline genomic signature
Trevino, LR; Yang, WJ; Hunger, S; Carroll, WL; Devidas, M; Willman, CL; Downing, J; Evans, WE; Pui, CH; Relling, MV
2007 NOV 16 ;110(11):234A-234A, Blood
— id: 76176, year: 2007, vol: 110, page: 234A, stat: Journal Article,

Isolated CNS relapse of acute lymphoblastic leukemia treated with intensive systemic chemotherapy and delayed CNS radiation: A pediatric oncology group study
Barredo, JC; Devidas, M; Lauer, SJ; Billett, A; Marymont, M; Pullen, J; Camitta, B; Winick, N; Carroll, W; Ritchey, AK
2006 JUL 1 ;24(19):3142-3149, Journal of clinical oncology
— id: 66452, year: 2006, vol: 24, page: 3142, stat: Journal Article,

Biologic pathways associated with relapse in childhood acute lymphoblastic leukemia: a Children's Oncology Group study
Bhojwani, Deepa; Kang, Huining; Moskowitz, Naomi P; Min, Dong-Joon; Lee, Hokyung; Potter, Jeffrey W; Davidson, George; Willman, Cheryl L; Borowitz, Michael J; Belitskaya-Levy, Ilana; Hunger, Stephen P; Raetz, Elizabeth A; Carroll, William L
2006 Jul 15;108(2):711-717, Blood
— id: 68296, year: 2006, vol: 108, page: 711, stat: Journal Article,

Childhood acute lymphoblastic leukemia in the age of genomics
Carroll, William L; Bhojwani, Deepa; Min, Dong-Joon; Moskowitz, Naomi; Raetz, Elizabeth A
2006 May 1;46(5):570-578, Pediatric blood & cancer
— id: 64130, year: 2006, vol: 46, page: 570, stat: Journal Article,

Outcomes after HLA-matched sibling transplantation or chemotherapy in children with B-precursor acute lymphoblastic leukemia in a second remission: a collaborative study of the Children's Oncology Group and the Center for International Blood and Marrow Transplant Research
Eapen, Mary; Raetz, Elizabeth; Zhang, Mei-Jie; Muehlenbein, Catherine; Devidas, Meenakshi; Abshire, Thomas; Billett, Amy; Homans, Alan; Camitta, Bruce; Carroll, William L; Davies, Stella M
2006 Jun 15;107(12):4961-4967, Blood
— id: 68297, year: 2006, vol: 107, page: 4961, stat: Journal Article,

Double delayed intensification (DDI) is equivalent to single DI (SDI) in children with national cancer institute (NCI) standard-risk acute lymphoblastic leukemia (SR-ALL) treated on children's cancer group (CCG) clinical trial 1991 (CCG-1991)
Matloub, Y; Angiolillo, A; Bostrom, B; Hunger, SP; Nachman, J; Sather, H; Carroll, WL; Winick, N; Gaynon, PS
2006 NOV 16 ;108(11):47A-48A, Blood
— id: 71380, year: 2006, vol: 108, page: 47A, stat: Journal Article,

Diverse pathways mediate chemotherapy-induced cell death in acute lymphoblastic leukemia cell lines
Min, Dong-Joon; Moskowitz, Naomi P; Brownstein, Carrie; Lee, Hokyung; Horton, Terzah M; Carroll, William L
2006 Nov;11(11):1977-1986, Apoptosis
— id: 74585, year: 2006, vol: 11, page: 1977, stat: Journal Article,

Eliminating a gold standard in childhood acute lymphoblastic leukemia?
Raetz, Elizabeth A; Carroll, William L
2006 Sep;47(3):242-244, Pediatric blood & cancer
— id: 68298, year: 2006, vol: 47, page: 242, stat: Journal Article,

Gene expression profiling reveals intrinsic differences between T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma
Raetz, Elizabeth A; Perkins, Sherrie L; Bhojwani, Deepa; Smock, Kristi; Philip, Mary; Carroll, William L; Min, Dong-Joon
2006 Aug;47(2):130-140, Pediatric blood & cancer
— id: 68299, year: 2006, vol: 47, page: 130, stat: Journal Article,

Gene expression pathways that distinguish diagnosis and relapse in childhood acute lymphoblastic leukemia
Bhojwani, D; Raetz, E; Moskowitz, N; Lee, H; Sohn, B; Hunger, SP; Carroll, WL
2005 NOV 16 ;106(11):250A-250A, Blood
— id: 61464, year: 2005, vol: 106, page: 250A, stat: Journal Article,

Building better therapy for children with acute lymphoblastic leukemia
Carroll, William L; Raetz, Elizabeth A
2005 Apr;7(4):289-291, Cancer cell
— id: 55998, year: 2005, vol: 7, page: 289, stat: Journal Article,

100 questions & answers about your child's cancer
Carroll, William L; Reisman, Jessica B
Sudbury MA : Jones and Bartlett, 2005,
— id: 1825, year: 2005, vol: , page: , stat: ,

Therapy of low-risk subsets of childhood acute lymphoblastic leukemia: When do we say enough?
Hunger, Stephen P; Winick, Naomi J; Sather, Harland N; Carroll, William L
2005 Dec;45(7):876-880, Pediatric blood & cancer
— id: 57591, year: 2005, vol: 45, page: 876, stat: Journal Article,

Gene signatures predictive of outcome in higher risk childhood acute lymphoblastic leukemia (ALL)
Moskowitz, NP; Bhojwani, D; Kang, H; Min, DJ; Potter, J; Harvey, R; Seibel, NL; Raetz, E; Sather, HN; Hunger, SP; Willman, CL; Carroll, WL
2005 NOV 16 ;106(11):418A-418A, Blood
— id: 61466, year: 2005, vol: 106, page: 418A, stat: Journal Article,

A gene expression classifier for improved risk classification and outcome prediction in pediatric acute lymphoblastic leukemia (ALL)
Willman, CL; Kang, HN; Potter, JW; Harvey, RC; Atlas, SR; Bedrick, E; Helman, P; Veroff, RL; Chen, IM; Carroll, AJ; Ar, K; Xu, YX; Murphy, SB; Bhojwani, D; Moskowitz, N; Carroll, WL; Camitta, B
2005 NOV 16 ;106(11):225A-225A, Blood
— id: 61463, year: 2005, vol: 106, page: 225A, stat: Journal Article,

Racial and ethnic factors in outcomes of children with acute lymphoblastic leukemia - Reply
Carroll, WL
2004 JUN 2 ;291(21):2541-2541, JAMA
— id: 46631, year: 2004, vol: 291, page: 2541, stat: Journal Article,

Autoregulation of the N-myc gene is operative in neuroblastoma and involves histone deacetylase 2
Kim, Marianne K H; Carroll, William L
2004 Nov 1;101(9):2106-2115, Cancer
— id: 57592, year: 2004, vol: 101, page: 2106, stat: Journal Article,

Childhood leukemia--new advances and challenges
Winick, Naomi J; Carroll, William L; Hunger, Stephen P
2004 Aug 5;351(6):601-603, New England journal of medicine
— id: 57593, year: 2004, vol: 351, page: 601, stat: Journal Article,

Race and outcome in childhood acute lymphoblastic leukemia
Carroll, William L
2003 Oct 15;290(15):2061-2063, JAMA
— id: 57594, year: 2003, vol: 290, page: 2061, stat: Journal Article,

Pediatric acute lymphoblastic leukemia
Carroll, William L; Bhojwani, Deepa; Min, Dong-Joon; Raetz, Elizabeth; Relling, Mary; Davies, Stella; Downing, James R; Willman, Cheryl L; Reed, John C
2003 ;50(4):102-131, Hematology (American Society of Hematology. Education Program)
— id: 45386, year: 2003, vol: 50, page: 102, stat: Journal Article,

Identification of genes that are regulated transcriptionally by Myc in childhood tumors
Raetz, Elizabeth A; Kim, Marianne K H; Moos, Philip; Carlson, Marlee; Bruggers, Carol; Hooper, David K; Foot, Laura; Liu, Tong; Seeger, Robert; Carroll, William L
2003 Aug 15;98(4):841-853, Cancer
— id: 57595, year: 2003, vol: 98, page: 841, stat: Journal Article,

Diversity of the apoptotic response to chemotherapy in childhood leukemia
Liu, T; Raetz, E; Moos, P J; Perkins, S L; Bruggers, C S; Smith, F; Carroll, W L
2002 Feb;16(2):223-232, Leukemia
— id: 57599, year: 2002, vol: 16, page: 223, stat: Journal Article,

Identification of gene expression profiles that segregate patients with childhood leukemia
Moos, Philip J; Raetz, Elizabeth A; Carlson, Marlee A; Szabo, Aniko; Smith, Fiona E; Willman, Cheryl; Wei, Qi; Hunger, Stephen P; Carroll, William L
2002 Oct;8(10):3118-3130, Clinical cancer research
— id: 57596, year: 2002, vol: 8, page: 3118, stat: Journal Article,

The nucleophosmin-anaplastic lymphoma kinase fusion protein induces c-Myc expression in pediatric anaplastic large cell lymphomas
Raetz, Elizabeth A; Perkins, Sherrie L; Carlson, Marlee A; Schooler, Kevin P; Carroll, William L; Virshup, David M
2002 Sep;161(3):875-883, American journal of pathology
— id: 57597, year: 2002, vol: 161, page: 875, stat: Journal Article,

Variable selection and pattern recognition with gene expression data generated by the microarray technology
Szabo, A; Boucher, K; Carroll, W L; Klebanov, L B; Tsodikov, A D; Yakovlev, A Y
2002 Mar;176(1):71-98, Mathematical biosciences
— id: 57598, year: 2002, vol: 176, page: 71, stat: Journal Article,

Gene expression profiling. Methods and clinical applications in oncology
Raetz EA; Moos PJ; Szabo A; Carroll WL
2001 Oct;15(5):'44'-'47', Hematology-oncology clinics of North America
— id: 57600, year: 2001, vol: 15, page: '44', stat: Journal Article,

Coexpression of genes involved in apoptosis in central nervous system neoplasms
Bruggers CS; Fults D; Perkins SL; Coffin CM; Carroll WL
1999 Jan-Feb;21(1):19-25, Journal of pediatric hematology/oncology
— id: 57602, year: 1999, vol: 21, page: 19, stat: Journal Article,

A novel intron element operates posttranscriptionally To regulate human N-myc expression
Sivak LE; Pont-Kingdon G; Le K; Mayr G; Tai KF; Stevens BT; Carroll WL
1999 Jan;19(1):155-163, Molecular & cellular biology
— id: 57603, year: 1999, vol: 19, page: 155, stat: Journal Article,

Definition of the human N-myc promoter region during development in a transgenic mouse model
Tai KF; Rogers SW; Pont-Kingdon G; Carroll WL
1999 Sep;46(3):255-262, Pediatric research
— id: 57601, year: 1999, vol: 46, page: 255, stat: Journal Article,

Somatic hypermutation in T-independent and T-dependent immune responses to Haemophilus influenzae type b polysaccharide
Adderson EE; Shackelford PG; Carroll WL
1998 Dec;89(3):240-246, Clinical immunology & immunopathology
— id: 57604, year: 1998, vol: 89, page: 240, stat: Journal Article,

Expression of the c-Myc protein in childhood medulloblastoma
Bruggers CS; Tai KF; Murdock T; Sivak L; Le K; Perkins SL; Coffin CM; Carroll WL
1998 Jan-Feb;20(1):18-25, Journal of pediatric hematology/oncology
— id: 57606, year: 1998, vol: 20, page: 18, stat: Journal Article,

The molecular biology of pediatric lymphomas
Goldsby RE; Carroll WL
1998 Jul-Aug;20(4):282-296, Journal of pediatric hematology/oncology
— id: 57605, year: 1998, vol: 20, page: 282, stat: Journal Article,

Autoregulation of the human N-myc oncogene is disrupted in amplified but not single-copy neuroblastoma cell lines
Sivak LE; Tai KF; Smith RS; Dillon PA; Brodeur GM; Carroll WL
1997 Oct 16;15(16):1937-1946, Oncogene
— id: 57607, year: 1997, vol: 15, page: 1937, stat: Journal Article,