Kenneth H Cadwell

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Ken Cadwell

Assistant Professor, Department of Microbiology
Skirball Institute

Contact Info

540-562 First Avenue
New York, NY 10016


Research Summary

The Cadwell Lab investigates how the immune system is controlled during infectious and inflammatory diseases. The immune system is tasked with defending against life-threatening infectious agents, but at the same time must avoid unnecessary reactions against beneficial microbes that are part of the microbiome. Such unwanted immune responses are implicated in a variety of chronic diseases including inflammatory bowel disease and cancer. A key research goal is to uncover the cell biological processes that control the immune response when confronted with the diverse infectious agents found in the environment. Ongoing projects include: (1) Identifying gene-microbe interactions that contribute to inflammatory bowel disease, (2) elucidating the role of the cellular process of autophagy in host-pathogen interactions, and (3) examining the viral component of the microbiome, also known as the virome.

Research Interests

Understanding how infectious agents and the microbiome regulate susceptibility to inflammatory disease.

Frenemies in the gut: Infectious agents that defy classification
Cadwell, K
2015-08-31; 1023-3830,Inflammation research - id: 1747752, year: 2015

Expanding the role of the virome: commensalism in the gut
Cadwell, Ken
2015-03-23; 0022-538x,Journal of virology - id: 1506722, year: 2015 Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

The Virome in Host Health and Disease
Cadwell, Ken
2015-06-11; 1097-4180,Immunity - id: 1620552, year: 2015 REVIEW

Gastrointestinal Dissemination and Transmission of Staphylococcus aureus following Bacteremia
Kernbauer, Elisabeth; Maurer, Katie; Torres, Victor J; Shopsin, Bo; Cadwell, Ken
2015-02-02; 0019-9567,Infection & immunity - id: 1448442, year: 2015 Journal Article

Autophagy Mediates Tolerance to Staphylococcus aureus Alpha-Toxin
Maurer, Katie; Reyes-Robles, Tamara; Alonzo, Francis 3rd; Durbin, Joan; Torres, Victor J; Cadwell, Ken
2015-04-06; 1934-6069,Cell host & microbe - id: 1519082, year: 2015 JOURNAL ARTICLE