Miroslaw S Brys

Biosketch / Results /

Miroslaw S Brys, M.D., Ph.D.

Assistant Professor;
Department of Neurology (Movement Disorders Div)

Clinical Addresses

240 East 38th Street
20th Floor
New York, NY 10016
Handicap Access: yes
Phone: 212-263-4838
Fax: 212-263-7721

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Medical Specialties


Medical Expertise

Blepharospasm, Movement Disorders



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Board Certification

2012 — Ab Psychiatry & Neurology - Neurology


1992-1998 — Jagiellonian University Medical College, Medical Education
2008-2009 — Mount Sinai School of Medicine (Bronx Prog.) (Internal Medicine), Internship
2008-2012 — NYU School of Medicine (Neurology), Residency Training
2012-2013 — NYU School of Medicine (Movement Disorders), Clinical Fellowships

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Research Summary

Dr. Brys completed residency training in neurology as well as clinical fellowship in Movement Disorders at NYU. He graduated from Jagiellonian University School of Medicine in Krakow, Poland and received a Ph.D. in neurological sciences from the same institution. His Ph.D. dissertation addressed modulation of cerebral blood flow autoregulation at rest and during physical exercise using transcranial Doppler ultrasound technology. He is a recipient of prestigious grant from The Kosciuszko Foundation. Before his residency, he worked as a postdoctoral scientist in the neuroimaging laboratory of Dr. Mony de Leon. Dr. Brys's research interests focus on the identification of early biomarkers of neurodegenerative diseases using advanced MRI and Positron Emission Tomography (PET) techniques and analysis of cerebrospinal fluid (CSF). Additionally, he has been engaged in research applications of transcranial magnetic stimulation (TMS) as a treatment modality altering brain plasticity in Parkinson's disease.

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All data from NYU Health Sciences Library Faculty Bibliography — -


TMS Enhances Retention of a Motor Skill in Parkinson's Disease
Moisello, Clara; Blanco, Daniella; Fontanesi, Cecilia; Lin, Jing; Biagioni, Milton; Kumar, Pawan; Brys, Miroslaw; Loggini, Andrea; Marinelli, Lucio; Abbruzzese, Giovanni; Quartarone, Angelo; Tononi, Giulio; Di Rocco, Alessandro; Ghilardi, Maria Felice
2014 Nov;:670-677, Brain stimulation
— id: 1416252, year: 2014, vol: , page: 670, stat: Journal Article,

Quantitative structural MRI and CSF biomarkers in early diagnosis of Alzheimer's disease
Brys, M; Glodzik, L; Mosconi, L; Switalski, R; De, Santi S; Pirraglia, E; Rich, K; Kim, B C; Mehta, P; Zinkowski, R; Pratico, D; Wallin, A; Zetterberg, H; Tsui, W H; Rusinek, H; Blennow, K; De, Leon M J
2011 2011;Advances(in):141-152, Advances in Alzheimer's disease
— id: 178864, year: 2011, vol: Advances, page: 141, stat: Journal Article,

Framingham cardiovascular risk profile correlates with impaired hippocampal and cortical vasoreactivity to hypercapnia
Glodzik, Lidia; Rusinek, Henry; Brys, Miroslaw; Tsui, Wai H; Switalski, Remigiusz; Mosconi, Lisa; Mistur, Rachel; Pirraglia, Elizabeth; de Santi, Susan; Li, Yi; Goldowsky, Alexander; de Leon, Mony J
2011 Feb;31(2):671-679, Journal of cerebral blood flow & metabolism
— id: 138222, year: 2011, vol: 31, page: 671, stat: Journal Article,

Metronomic breathing shows altered parasympathetic baroreflex function in untreated Fabry patients and baroreflex improvement after enzyme replacement therapy
Hilz, Max J; Koehn, Julia; Kolodny, Edwin H; Brys, Miroslaw; Moeller, Sebastian; Stemper, Brigitte
2011 Dec;29(12):2387-2394, Journal of hypertension
— id: 141327, year: 2011, vol: 29, page: 2387, stat: Journal Article,

Hippocampal blood flow in normal aging measured with arterial spin labeling at 3T
Rusinek, Henry; Brys, Miroslaw; Glodzik, Lidia; Switalski, Remigiusz; Tsui, Wai-Hon; Haas, Francois; McGorty, Kellyanne; Chen, Qun; de Leon, Mony J
2011 Jan;65(1):128-137, Magnetic resonance in medicine
— id: 116206, year: 2011, vol: 65, page: 128, stat: Journal Article,

Cardiac responses to orthostatic stress deteriorate in Parkinson disease patients who begin to fall
Czarkowska, Hanna; Tutaj, Marcin; Rudzinska, Monika; Motyl, Maciej; Brys, Miroslaw; Bukowczan, Sylwia; Kyrcz, Anna; Zajdel, Katarzyna; Szczudlik, Andrzej
2010 Jul-Aug;44(4):339-349, Neurologia i neurochirurgia polska
— id: 363102, year: 2010, vol: 44, page: 339, stat: Journal Article,

Enzyme replacement therapy improves cardiovascular responses to orthostatic challenge in Fabry patients
Hilz, Max J; Marthol, Harald; Schwab, Stefan; Kolodny, Edwin H; Brys, Miroslaw; Stemper, Brigitte
2010 Jul;28(7):1438-1448, Journal of hypertension
— id: 138172, year: 2010, vol: 28, page: 1438, stat: Journal Article,

Magnetic resonance imaging improves cerebrospinal fluid biomarkers in the early detection of Alzheimer's disease
Brys, Miroslaw; Glodzik, Lidia; Mosconi, Lisa; Switalski, Remigiusz; De Santi, Susan; Pirraglia, Elizabeth; Rich, Kenneth; Kim, Byeong C; Mehta, Pankaj; Zinkowski, Ray; Pratico, Domenico; Wallin, Anders; Zetterberg, Henrik; Tsui, Wai H; Rusinek, Henry; Blennow, Kaj; de Leon, Mony J
2009 Feb;16(2):351-362, Journal of Alzheimer's disease
— id: 93784, year: 2009, vol: 16, page: 351, stat: Journal Article,

Prediction and longitudinal study of CSF biomarkers in mild cognitive impairment
Brys, Miroslaw; Pirraglia, Elizabeth; Rich, Kenneth; Rolstad, Sindre; Mosconi, Lisa; Switalski, Remigiusz; Glodzik-Sobanska, Lidia; De Santi, Susan; Zinkowski, Ray; Mehta, Pankaj; Pratico, Domenico; Saint Louis, Leslie A; Wallin, Anders; Blennow, Kaj; de Leon, Mony J
2009 May;30(5):682-690, Neurobiology of aging
— id: 86777, year: 2009, vol: 30, page: 682, stat: Journal Article,

Effects of memantine on cerebrospinal fluid biomarkers of neurofibrillary pathology
Glodzik, Lidia; De Santi, Susan; Rich, Kenneth E; Brys, Miroslaw; Pirraglia, Elizabeth; Mistur, Rachel; Switalski, Remigiusz; Mosconi, Lisa; Sadowski, Martin; Zetterberg, Henrik; Blennow, Kaj; de Leon, Mony J
2009 Nov;18(3):509-513, Journal of Alzheimer's disease
— id: 108783, year: 2009, vol: 18, page: 509, stat: Journal Article,

The effects of normal aging and ApoE genotype on the levels of CSF biomarkers for Alzheimer's disease
Glodzik-Sobanska, Lidia; Pirraglia, Elizabeth; Brys, Miroslaw; de Santi, Susan; Mosconi, Lisa; Rich, Kenneth E; Switalski, Remigiusz; Saint Louis, Leslie; Sadowski, Martin J; Martiniuk, Frank; Mehta, Pankaj; Pratico, Domenico; Zinkowski, Raymond P; Blennow, Kaj; de Leon, Mony J
2009 May;30(5):672-681, Neurobiology of aging
— id: 159206, year: 2009, vol: 30, page: 672, stat: Journal Article,

TNF-alpha and antibodies to periodontal bacteria discriminate between Alzheimer's disease patients and normal subjects
Kamer, Angela R; Craig, Ronald G; Pirraglia, Elizabeth; Dasanayake, Ananda P; Norman, Robert G; Boylan, Robert J; Nehorayoff, Andrea; Glodzik, Lidia; Brys, Miroslaw; de Leon, Mony J
2009 Nov;216(1-2):92-97, Journal of neuroimmunology
— id: 156192, year: 2009, vol: 216, page: 92, stat: Journal Article,

Declining brain glucose metabolism in normal individuals with a maternal history of Alzheimer disease
Mosconi, L; Mistur, R; Switalski, R; Brys, M; Glodzik, L; Rich, K; Pirraglia, E; Tsui, W; De Santi, S; de Leon, M J
2009 Feb 10;72(6):513-520, Neurology
— id: 93785, year: 2009, vol: 72, page: 513, stat: Journal Article,

An entorhinal cortex sulcal pattern is associated with Alzheimer's disease
Zhan, Jiong; Brys, Miroslaw; Glodzik, Lidia; Tsui, Wai; Javier, Elizabeth; Wegiel, Jerzy; Kuchna, Izabela; Pirraglia, Elizabeth; Li, Yi; Mosconi, Lisa; Saint Louis, Leslie A; Switalski, Remigiusz; De Santi, Susan; Kim, Byeong C; Wisniewski, Thomas; Reisberg, Barry; Bobinski, Matthew; de Leon, Mony J
2009 Mar;30(3):874-882, Human brain mapping
— id: 76758, year: 2009, vol: 30, page: 874, stat: Journal Article,

Robust and conventional neuropsychological norms: diagnosis and prediction of age-related cognitive decline
De Santi, Susan; Pirraglia, Elizabeth; Barr, William; Babb, James; Williams, Schantel; Rogers, Kimberley; Glodzik, Lidia; Brys, Miroslaw; Mosconi, Lisa; Reisberg, Barry; Ferris, Steven; de Leon, Mony J
2008 Jul;22(4):469-484, Neuropsychology
— id: 86549, year: 2008, vol: 22, page: 469, stat: Journal Article,

Inflammation and Alzheimer's disease: possible role of periodontal diseases
Kamer, Angela R; Craig, Ronald G; Dasanayake, Ananda P; Brys, Miroslaw; Glodzik-Sobanska, Lidia; de Leon, Mony J
2008 Jul;4(4):242-250, Alzheimer's & dementia
— id: 156668, year: 2008, vol: 4, page: 242, stat: Journal Article,

Hypometabolism and altered cerebrospinal fluid markers in normal apolipoprotein E E4 carriers with subjective memory complaints
Mosconi, Lisa; De Santi, Susan; Brys, Miroslaw; Tsui, Wai H; Pirraglia, Elizabeth; Glodzik-Sobanska, Lidia; Rich, Kenneth E; Switalski, Remigius; Mehta, Pankaj D; Pratico, Domenico; Zinkowski, Ray; Blennow, Kay; de Leon, Mony J
2008 Mar 15;63(6):609-618, Biological psychiatry
— id: 78013, year: 2008, vol: 63, page: 609, stat: Journal Article,

Imaging and CSF studies in the preclinical diagnosis of Alzheimer's disease
de Leon, M J; Mosconi, L; Blennow, K; DeSanti, S; Zinkowski, R; Mehta, P D; Pratico, D; Tsui, W; Saint Louis, L A; Sobanska, L; Brys, M; Li, Y; Rich, K; Rinne, J; Rusinek, H
2007 Feb;1097:114-145, Annals of the New York Academy of Sciences
— id: 71870, year: 2007, vol: 1097, page: 114, stat: Journal Article,

Longitudinal CSF isoprostane and MRI atrophy in the progression to AD
de Leon, M J; Mosconi, L; Li, J; De Santi, S; Yao, Y; Tsui, W H; Pirraglia, E; Rich, K; Javier, E; Brys, M; Glodzik, L; Switalski, R; Saint Louis, L A; Pratico, D
2007 Dec;254(12):1666-1675, Journal of neurology
— id: 78349, year: 2007, vol: 254, page: 1666, stat: Journal Article,

Subjective memory complaints: presence, severity and future outcome in normal older subjects
Glodzik-Sobanska, Lidia; Reisberg, Barry; De Santi, Susan; Babb, James S; Pirraglia, Elizabeth; Rich, Kenneth E; Brys, Miroslaw; de Leon, Mony J
2007 ;24(3):177-184, Dementia geriatric & cognitive disorders
— id: 73937, year: 2007, vol: 24, page: 177, stat: Journal Article,

Early detection of Alzheimer's disease using neuroimaging
Mosconi, Lisa; Brys, Miroslaw; Glodzik-Sobanska, Lidia; De Santi, Susan; Rusinek, Henry; de Leon, Mony J
2007 Jan-Feb;42(1-2):129-138, Experimental gerontology
— id: 70031, year: 2007, vol: 42, page: 129, stat: Journal Article,

Maternal family history of Alzheimer's disease predisposes to reduced brain glucose metabolism
Mosconi, Lisa; Brys, Miroslaw; Switalski, Remigiusz; Mistur, Rachel; Glodzik, Lidia; Pirraglia, Elizabeth; Tsui, Wai; De Santi, Susan; de Leon, Mony J
2007 Nov 27;104(48):19067-19072, Proceedings of the National Academy of Sciences of the United States of America (PNAS)
— id: 75484, year: 2007, vol: 104, page: 19067, stat: Journal Article,

Cerebrospinal fluid biomarkers for mild cognitive impairment
Brys M; Mosconi L; De Santi S; Rich K; de Leon MJ
2006 ;2(1):111-121, Aging health
— id: 64335, year: 2006, vol: 2, page: 111, stat: Journal Article,

[Vascular abnormalities in patients with primary intracerebral hemorrhage]
Slowik, Agnieszka; Szermer, Pawel; Turaj, Wojciech; Glodzik-Sobanska, Lidia; Dziedzic, Tomasz; Pera, Joanna; Brys, Miroslaw; Uhl, Henryka; Szczudlik, Andrzej
2006 ;63(8):616-619, Przeglad lekarski
— id: 86776, year: 2006, vol: 63, page: 616, stat: Journal Article,

The role of quantitative structural imaging in the early diagnosis of Alzheimer's disease
Glodzik-Sobanska, Lidia; Rusinek, Henry; Mosconi, Lisa; Li, Yi; Zhan, Jiong; de Santi, Susan; Convit, Antonio; Rich, Kenneth; Brys, Miroslaw; de Leon, Mony J
2005 Nov;15(4):340-341, Neuroimaging clinics of North America
— id: 64158, year: 2005, vol: 15, page: 340, stat: Journal Article,

Enzyme replacement therapy improves function of C-, Adelta-, and Abeta-nerve fibers in Fabry neuropathy
Hilz, M J; Brys, M; Marthol, H; Stemper, B; Dutsch, M
2004 May 13;62(7):1066-1072, Neurology
— id: 46022, year: 2004, vol: 62, page: 1066, stat: Journal Article,

Assessing function and pathology in familial dysautonomia: assessment of temperature perception, sweating and cutaneous innervation
Hilz, Max J; Axelrod, Felicia B; Bickel, Andreas; Stemper, Brigitte; Brys, Miroslaw; Wendelschafer-Crabb, Gwen; Kennedy, William R
2004 Oct;127(Pt 9):2090-2098, Brain
— id: 46110, year: 2004, vol: 127, page: 2090, stat: Journal Article,

Reduced cerebral blood flow velocity and impaired cerebral autoregulation in patients with Fabry disease
Hilz, Max Josef; Kolodny, Edwin H; Brys, Miroslaw; Stemper, Brigitte; Haendl, Thomas; Marthol, Harald
2004 Jun;251(5):564-570, Journal of neurology
— id: 46144, year: 2004, vol: 251, page: 564, stat: Journal Article,

Dynamic cerebral autoregulation is impaired in glaucoma
Tutaj, Marcin; Brown, Clive M; Brys, Miroslaw; Marthol, Harald; Hecht, Martin J; Dutsch, Matthias; Michelson, Georg; Hilz, Max J
2004 May 15;220(1-2):49-54, Journal of the neurological sciences
— id: 68227, year: 2004, vol: 220, page: 49, stat: Journal Article,

Orthostatic challenge reveals impaired vascular resistance control, but normal venous pooling and capillary filtration in familial dysautonomia
Brown, Clive M; Stemper, Brigitte; Welsch, Gotz; Brys, Miroslaw; Axelrod, Felicia B; Hilz, Max J
2003 Feb;104(2):163-169, Clinical science (London, 1979)
— id: 37000, year: 2003, vol: 104, page: 163, stat: Journal Article,

Dynamic cerebral autoregulation remains stable during physical challenge in healthy persons
Brys, Miroslaw; Brown, Clive M; Marthol, Harald; Franta, Renate; Hilz, Max J
2003 Sep;285(3):H1048-H1054, American journal of physiology. Heart & circulatory physiology
— id: 36987, year: 2003, vol: 285, page: H1048, stat: Journal Article,

Clonidine improves postprandial baroreflex control in familial dysautonomia
Marthol, H; Tutaj, M; Brys, M; Brown, C M; Hecht, M J; Berlin, D; Axelrod, F B; Hilz, M J
2003 Oct;33(10):912-918, European journal of clinical investigation
— id: 39055, year: 2003, vol: 33, page: 912, stat: Journal Article,

Terminal vessel hyperperfusion despite organ hypoperfusion in familial dysautonomia
Stemper, Brigitte; Axelrod, Felicia B; Marthol, Harald; Brown, Clive; Brys, Miroslav; Welsch, Goetz; Hilz, Max J
2003 Sep;105(3):295-301, Clinical science (London, 1979)
— id: 36996, year: 2003, vol: 105, page: 295, stat: Journal Article,

Small fiber dysfunction predominates in Fabry neuropathy
Dutsch, M; Marthol, H; Stemper, B; Brys, M; Haendl, T; Hilz, M J
2002 Dec;19(6):575-586, Journal of clinical neurophysiology
— id: 37005, year: 2002, vol: 19, page: 575, stat: Journal Article,

Stability of autonomic cardiovascular modulation and baroreflex function during Sildenafil use and physical challenge
Hilz, MJ; Stemper, B; Brys, M; Marthol, H; Franta, R; Axelrod, FB
2002 ;58(7):A348-A349, Neurology
— id: 104750, year: 2002, vol: 58, page: A348, stat: Journal Article,