Stuart M. Brown

Biosketch / Results /

Stuart Brown

Associate Professor, Department of Cell Biology
Cell Biology

Contact Info

Address
227 East 30th Street
New York, NY 10016

212/263-7689
Stuart.Brown@nyumc.org


Education

— Dr. Brown was a Postdoctoral Fellow in Plant Molecular Biology and the University of Manitoba and subsequently a Research Scientist at the USDA-ARS Plant Genetics Resources Unit in Griffin, GA, PostDoctoral Training
1992 — Cornell University, Graduate Education

Research Summary

Bioinformatics is a rapidly growing area that addresses the use of computers for the acquisition, management, and analysis of biological information. The explosion of interest in bioinformatics in the past few years has been driven by the tremendous growth of DNA sequencing technology. Investigators use sequencing techniques for a variety of genomics applications but requrie bioinformatics skills to support this work.



I act as bioinformatics consultant for NYU Medical Center, collaborating as needed on a wide range of research projects. The extent of these collaborations ranges from a few consultation meetings to co-investigator on NIH grants. I am currently working on projects that include metagenomics (Human Microbiome Project), the genetic variation in the malaria parasite, and analysis of RNA-seq data from a variety of clinical and basic science research projects. Other projects that I have recently worked on include discovery of antigens using a pattern based search of complete genome sequences, Search for bacterial genes linked to severe dental caries, and an evolutionary analysis of the mammalian glucosidase gene family.

Research Interests

Bioinformatics

Pathogenicity island-directed transfer of unlinked chromosomal virulence genes
Chen, John; Ram, Geeta; Penades, Jose R; Brown, Stuart; Novick, Richard P
2015-02-04; 1097-2765,Molecular cell - id: 1449882, year: 2015 Journal Article

Identification of a Face Enhancer Reveals Direct Regulation of LIM homeobox 8 (Lhx8) by Wingless-Int (WNT)/beta-catenin Signaling
Landin Malt, Andre; Cesario, Jeffry M; Tang, Zuojian; Brown, Stuart; Jeong, Juhee
2014-09-07; 0021-9258,Journal of biological chemistry - id: 1173362, year: 2014 JOURNAL ARTICLE

Identification of a face enhancer reveals direct regulation of LIM homeobox 8 (Lhx8) by wingless-int (WNT)/.-catenin signaling
Malt, AL; Cesario, JM; Tang, Z; Brown, S; Jeong, J
2015-02-06; 0021-9258,Journal of biological chemistry - id: 1453592, year: 2014

Global reprogramming of the cellular translational landscape facilitates cytomegalovirus replication
McKinney, Caleb; Zavadil, Jiri; Bianco, Christopher; Shiflett, Lora; Brown, Stuart; Mohr, Ian
2014-01-27; 2211-1247,Cell reports - id: 759792, year: 2014 Journal Article

FIREWACh: high-throughput functional detection of transcriptional regulatory modules in mammalian cells
Murtha, Matthew; Tokcaer-Keskin, Zeynep; Tang, Zuojian; Strino, Francesco; Chen, Xi; Wang, Yatong; Xi, Xiangmei; Basilico, Claudio; Brown, Stuart; Bonneau, Richard; Kluger, Yuval; Dailey, Lisa
2014-05-12; 1548-7091,Nature methods - id: 970072, year: 2014 Journal Article