Jonathan D Brodie

Biosketch / Results /

Jonathan D Brodie, M.D., Ph.D.

Professor;
Department of Psychiatry (VA)

Clinical Addresses

155 East 38 Street
New York, NY 10016
Phone: 212-986-6693
Fax: 212-263-8153

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Medical Specialties

Psychiatry

Dr. Brodie is a reviewer for various neuroimaging and psychiatric journals, and as an ad hoc member of several NIH review committees. He is a visiting investigator in the Chemistry department of Brookhaven National Laboratories. he is also a member of the Promotions and Tenure committee of the NYU School of Medicine.

Insurance

HealthNet

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Board Certification

1999 — Ab Psychiatry & Neurology - Psychiatry

Education

1975 — New York University School of Medicine, Medical Education
1975-1978 — NYU Medical Center (Psychiatry), Residency Training

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Research Summary

For many years, Dr. Brodie has maintained a close collaboration with Dr. Stephen Dewey and the PET group of Brookhaven National Laboratory. This effort has focused on the investigation of neurotransmitter interactions and their application to clinical issues. We use PET neuroimaging methods with pharmacological perturbations as probes and changes in binding of radioligands to specific neuroreceptors as outcome measures. We pair these human and non-human primate studies with microdialysis studies and behavioral observations as independent measures. With this strategy, we have established that the hallmark of any functioning psychoactive drug is chemical plasticity, expressed as neurotransmitter interactions, i.e. the ability to transmit and transduce a chemical signal to brain regions that may be distinguished in space and/or time. We are actively investigating the complexity of this accommodation with pharmacologic probes in non-human primates, normal controls and patient populations. Measurement of these interactions with PET is now an accepted method for examining pharmacological activity in vivo. Initially, we developed probes to investigate the ability of one neurotransmitter to modulate or be modulated by another functionally linked neurotransmitter system by using multiple radiotracers and pharmacologically specific challenges in the study of schizophrenia. These early studies have since evolved to encompass such areas as neuroleptic response and neurotransmitter stability. More recently our studies of GABAergic modulation of dopamine have led to the exciting findings that the suicide inhibitor of GABA transaminase, GVG, is an extraordinarily effective drug in blocking the use of virtually all drugs of abuse, including cocaine, nicotine, heroin, alcohol, methamphetamine and others. We are actively involved in the extension of these studies to human patients.

Research Interests

Functional neuroimaging of pharmacological activity; The relationship of neural plasticity to the emergence of psychopathology

Research Keywords

brain imaging, neurochemical plasticity, positron emission tomography (PET), psychopharmacology, schizophrenia

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

(1S, 3S)-3-Amino-4-difluoromethylenyl-1-cyclopentanoic Acid (CPP-115), a Potent gamma-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Cocaine Addiction
Pan, Yue; Gerasimov, Madina R; Kvist, Trine; Wellendorph, Petrine; Madsen, Karsten K; Pera, Elena; Lee, Hyunbeom; Schousboe, Arne; Chebib, Mary; Brauner-Osborne, Hans; Craft, Cheryl M; Brodie, Jonathan D; Schiffer, Wynne K; Dewey, Stephen L; Miller, Steven R; Silverman, Richard B
2012 Jan 12;55(1):357-366, Journal of medicinal chemistry
— id: 150262, year: 2012, vol: 55, page: 357, stat: Journal Article,

Integrating molecular imaging and behavioral neuroscience: Seeing animal models in a new light
Schiffer W.; Carrion J.; Eidelberg D.; Brodie J.D.
2010 ;12:S664-S664, Molecular imaging & biology
— id: 119244, year: 2010, vol: 12, page: S664, stat: Journal Article,

Randomized, Double-Blind, Placebo-Controlled Trial of Vigabatrin for the Treatment of Cocaine Dependence in Mexican Parolees
Brodie, Jonathan D; Case, Brady G; Figueroa, Emilia; Dewey, Stephen L; Robinson, James A; Wanderling, Joseph A; Laska, Eugene M
2009 Nov;166(11):1269-1277, American journal of psychiatry
— id: 101865, year: 2009, vol: 166, page: 1269, stat: Journal Article,

Racemic gamma vinyl-GABA (R,S-GVG) blocks methamphetamine-triggered reinstatement of conditioned place preference
DeMarco, Amy; Dalal, Reema M; Pai, Jessica; Aquilina, Stefanie D; Mullapudi, Uma; Hammel, Crystie; Kothari, Shiva K; Kahanda, Milan; Liebling, Courtney N B; Patel, Vinal; Schiffer, Wynne K; Brodie, Jonathan D; Dewey, Stephen L
2009 Feb;63(2):87-94, Synapse
— id: 95221, year: 2009, vol: 63, page: 87, stat: Journal Article,

Cue-induced dopamine release predicts cocaine preference: positron emission tomography studies in freely moving rodents
Schiffer, Wynne K; Liebling, Courtney N B; Reiszel, Corinne; Hooker, Jacob M; Brodie, Jonathan D; Dewey, Stephen L
2009 May 13;29(19):6176-6185, Journal of neuroscience
— id: 109179, year: 2009, vol: 29, page: 6176, stat: Journal Article,

Subchronic racemic gamma vinyl-GABA produces weight loss in Sprague Dawley and Zucker fatty rats
DeMarco, Amy; Dalal, Reema M; Kahanda, Milan; Mullapudi, Uma; Pai, Jessica; Hammel, Crystie; Liebling, Courtney N B; Patel, Vinal; Brodie, Jonathan D; Schiffer, Wynne K; Dewey, Stephen L; Aquilina, Stefanie D
2008 Nov;62(11):870-872, Synapse
— id: 95222, year: 2008, vol: 62, page: 870, stat: Journal Article,

Gamma-vinyl GABA inhibits cocaine-triggered reinstatement of drug-seeking behavior in rats by a non-dopaminergic mechanism
Peng, Xiao-Qing; Li, Xia; Gilbert, Jeremy G; Pak, Arlene C; Ashby, Charles R Jr; Brodie, Jonathan D; Dewey, Stephen L; Gardner, Eliot L; Xi, Zheng-Xiong
2008 Oct 1;97(3):216-225, Drug & alcohol dependence
— id: 76198, year: 2008, vol: 97, page: 216, stat: Journal Article,

The brain and behavior: limitations in the legal use of functional magnetic resonance imaging
Tancredi, Laurence R; Brodie, Jonathan D
2007 ;33(2-3):271-294, American journal of law & medicine
— id: 75386, year: 2007, vol: 33, page: 271, stat: Journal Article,

Correlation of PET and qEEG in normal subjects
Alper, Kenneth R; John, E Roy; Brodie, Jonathan; Gunther, Wilfred; Daruwala, Raoul; Prichep, Leslie S
2006 Apr 30;146(3):271-282, Psychiatry research
— id: 67000, year: 2006, vol: 146, page: 271, stat: Journal Article,

Metabolic correlates of toluene abuse: decline and recovery of function in adolescent animals
Dewey, Stephen L; Ferrieri, Rich; Alexoff, David L; Schiffer, Wynne K; Lee, Dianne E; Brodie, Jonathan D
2006 Jun;186(2):159-167, Psychopharmacology
— id: 67949, year: 2006, vol: 186, page: 159, stat: Journal Article,

Short-term Treatment of Cocaine and/or Methamphetamine Abuse With Vigabatrin: Ocular Safety Pilot Results
Fechtner, Robert D; Khouri, Albert S; Figueroa, Emilia; Ramirez, Marina; Federico, Martha; Dewey, Stephen L; Brodie, Jonathan D
2006 Sep;124(9):1257-1262, Archives of ophthalmology (1960)
— id: 67948, year: 2006, vol: 124, page: 1257, stat: Journal Article,

Safety and efficacy of gamma-vinyl GABA (GVG) for the treatment of methamphetamine and/or cocaine addiction
Brodie, Jonathan D; Figueroa, Emilia; Laska, Eugene M; Dewey, Stephen L
2005 Feb;55(2):122-125, Synapse
— id: 46891, year: 2005, vol: 55, page: 122, stat: Journal Article,

Imaging addiction with PET: is insight in sight?
Schiffer, Wynne K; Lee, Dianne E; Brodie, Jonathan D; Dewey, Stephen L
2005 Apr 15;10(8):547-562, Drug discovery today
— id: 67950, year: 2005, vol: 10, page: 547, stat: Journal Article,

Treating cocaine addiction: from preclinical to clinical trial experience with gamma-vinyl GABA
Brodie, Jonathan D; Figueroa, Emilia; Dewey, Stephen L
2003 Dec 1;50(3):261-265, Synapse
— id: 39052, year: 2003, vol: 50, page: 261, stat: Journal Article,

Limitations of brain imaging in forensic psychiatry
Reeves, Donald; Mills, Mark J; Billick, Stephen B; Brodie, Jonathan D
2003 ;31(1):89-96, Journal of the American Academy of Psychiatry & the Law
— id: 45033, year: 2003, vol: 31, page: 89, stat: Journal Article,

Gamma-vinyl GABA, an irreversible inhibitor of GABA transaminase, alters the acquisition and expression of cocaine-induced sensitization in male rats
Gardner, Eliot L; Schiffer, Wynne K; Horan, Bryan A; Highfield, David; Dewey, Stephen L; Brodie, Jonathan D; Ashby, Charles R Jr
2002 Dec 15;46(4):240-250, Synapse
— id: 67951, year: 2002, vol: 46, page: 240, stat: Journal Article,

GABAergic blockade of cocaine-associated cue-induced increases in nucleus accumbens dopamine
Gerasimov MR; Schiffer WK; Gardner EL; Marsteller DA; Lennon IC; Taylor SJ; Brodie JD; Ashby CR; Dewey SL
2001 Mar 2;414(2-3):205-209, European journal of pharmacology
— id: 18575, year: 2001, vol: 414, page: 205, stat: Journal Article,

The selective sigma(1) receptor agonist, 1-(3,4-dimethoxyphenethyl)-4-(phenylpropyl)piperazine (SA4503), blocks the acquisition of the conditioned place preference response to (-)-nicotine in rats
Horan, B; Gardner, E L; Dewey, S L; Brodie, J D; Ashby, C R Jr
2001 Aug 24;426(1-2):R1-R2, European journal of pharmacology
— id: 76268, year: 2001, vol: 426, page: R1, stat: Journal Article,

Gamma-vinyl GABA (GVG) blocks expression of the conditioned place preference response to heroin in rats
Paul, M; Dewey, S L; Gardner, E L; Brodie, J D; Ashby, C R Jr
2001 Sep 1;41(3):219-220, Synapse
— id: 76221, year: 2001, vol: 41, page: 219, stat: Journal Article,

Gamma vinyl-GABA differentially modulates NMDA antagonist-induced increases in mesocortical versus mesolimbic DA transmission
Schiffer, W K; Gerasimov, M; Hofmann, L; Marsteller, D; Ashby, C R; Brodie, J D; Alexoff, D L; Dewey, S L
2001 Nov;25(5):704-712, Neuropsychopharmacology
— id: 76217, year: 2001, vol: 25, page: 704, stat: Journal Article,

Manipulations in mechanical ventilation influence the transport constant (K-1) of the reversible radiotracer C-11-cocaine
Schiffer, WK; Carter, P; Alexoff, DL; Fowler, JS; Logan, J; Shea, C; Gerasimov, M; Brodie, J; Dewey, S
2001 MAY ;42(5):213P-213P, Journal of nuclear medicine
— id: 55050, year: 2001, vol: 42, page: 213P, stat: Journal Article,

MK-801 increases dopamine transporter (DAT) availability: A positron emission tomography (PET) investigation in non-human primates
Schiffer, WK; Gerasimov, MR; Fowler, JS; Volkow, ND; Gifford, A; Ashby, CR; Brodie, JD; Dewey, SL
2001 MAY ;42(5):16P-16P, Journal of nuclear medicine
— id: 55049, year: 2001, vol: 42, page: 16P, stat: Journal Article,

Positron emission tomography (PET) investigations of synaptic dopamine (DA) release and re-uptake in phencyclidine (PCP) treated primates
Schiffer, WK; Gerasimov, MR; Fowler, JS; Volkow, ND; Logan, J; Alexoff, DL; Shea, C; Brodie, JD; Dewey, SL
2001 MAY ;42(5):15P-15P, Journal of nuclear medicine
— id: 55048, year: 2001, vol: 42, page: 15P, stat: Journal Article,

gamma-aminobutyric acid mimetic drugs differentially inhibit the dopaminergic response to cocaine
Gerasimov MR; Schiffer WK; Brodie JD; Lennon IC; Taylor SJ; Dewey SL
2000 Apr 28;395(2):129-135, European journal of pharmacology
— id: 18576, year: 2000, vol: 395, page: 129, stat: Journal Article,

Stereoselective inhibition of dopaminergic activity by gamma vinyl-GABA following a nicotine or cocaine challenge: a PET/microdialysis study
Schiffer WK; Gerasimov MR; Bermel RA; Brodie JD; Dewey SL
2000 Feb 18;66(13):PL169-PL173, Life sciences
— id: 11786, year: 2000, vol: 66, page: PL169, stat: Journal Article,

Implication of the GABA(B) receptor in gamma vinyl-GABA's inhibition of cocaine-induced increases in nucleus accumbens dopamine
Ashby CR; Rohatgi R; Ngosuwan J; Borda T; Gerasimov MR; Morgan AE; Kushner S; Brodie JD; Dewey SL
1999 Feb;31(2):151-153, Synapse
— id: 18578, year: 1999, vol: 31, page: 151, stat: Journal Article,

A pharmacologic strategy for the treatment of nicotine addiction
Dewey SL; Brodie JD; Gerasimov M; Horan B; Gardner EL; Ashby CR Jr
1999 Jan;31(1):76-86, Synapse
— id: 57135, year: 1999, vol: 31, page: 76, stat: Journal Article,

Gamma-vinyl GABA inhibits methamphetamine, heroin, or ethanol-induced increases in nucleus accumbens dopamine
Gerasimov MR; Ashby CR; Gardner EL; Mills MJ; Brodie JD; Dewey SL
1999 Oct;34(1):11-19, Synapse
— id: 18577, year: 1999, vol: 34, page: 11, stat: Journal Article,

Task-specific deactivation patterns in functional magnetic resonance imaging
Hutchinson M; Schiffer W; Joseffer S; Liu A; Schlosser R; Dikshit S; Goldberg E; Brodie JD
1999 Dec;17(10):1427-1436, Magnetic resonance imaging
— id: 11891, year: 1999, vol: 17, page: 1427, stat: Journal Article,

Correlation of qEEG with PET in schizophrenia
Alper K; Gunther W; Prichep LS; John ER; Brodie J
1998 ;38(1):50-56, Neuropsychobiology
— id: 7481, year: 1998, vol: 38, page: 50, stat: Journal Article,

Effect of a haloperidol challenge on regional brain metabolism in neuroleptic-responsive and nonresponsive schizophrenic patients
Bartlett EJ; Brodie JD; Simkowitz P; Schlosser R; Dewey SL; Lindenmayer JP; Rusinek H; Wolkin A; Cancro R; Schiffer W
1998 Mar;155(3):337-343, American journal of psychiatry
— id: 7497, year: 1998, vol: 155, page: 337, stat: Journal Article,

A novel strategy for the treatment of cocaine addiction
Dewey SL; Morgan AE; Ashby CR Jr; Horan B; Kushner SA; Logan J; Volkow ND; Fowler JS; Gardner EL; Brodie JD
1998 Oct;30(2):119-129, Synapse
— id: 57134, year: 1998, vol: 30, page: 119, stat: Journal Article,

A new gabaergic strategy for treating cocaine addiction
Dewey, SL; Morgan, AE; Ashby, CR; Logan, J; Kushner, SA; Kornetsky, C; Volkow, ND; Fowler, JS; Brodie, JD
1998 MAY ;39(5):388-69, Journal of nuclear medicine
— id: 98344, year: 1998, vol: 39, page: 388, stat: Journal Article,

Long-term stability of neurotransmitter activity investigated with 11C-raclopride PET
Schlosser R; Brodie JD; Dewey SL; Alexoff D; Wang GJ; Fowler JS; Volkow N; Logan J; Wolf AP
1998 Jan;28(1):66-70, Synapse
— id: 7781, year: 1998, vol: 28, page: 66, stat: Journal Article,

Functional magnetic resonance imaging of human brain activity in a verbal fluency task
Schlosser R; Hutchinson M; Joseffer S; Rusinek H; Saarimaki A; Stevenson J; Dewey SL; Brodie JD
1998 Apr;64(4):492-498, Journal of neurology neurosurgery & psychiatry
— id: 57250, year: 1998, vol: 64, page: 492, stat: Journal Article,

Glutamate modulation of dopamine measured in vivo with positron emission tomography (PET) and 11C-raclopride in normal human subjects
Smith GS; Schloesser R; Brodie JD; Dewey SL; Logan J; Vitkun SA; Simkowitz P; Hurley A; Cooper T; Volkow ND; Cancro R
1998 Jan;18(1):18-25, Neuropsychopharmacology
— id: 12191, year: 1998, vol: 18, page: 18, stat: Journal Article,

GABAergic attenuation of cocaine-induced dopamine release and locomotor activity
Dewey, S L; Chaurasia, C S; Chen, C E; Volkow, N D; Clarkson, F A; Porter, S P; Straughter-Moore, R M; Alexoff, D L; Tedeschi, D; Russo, N B; Fowler, J S; Brodie, J D
1997 Apr;25(4):393-398, Synapse
— id: 76225, year: 1997, vol: 25, page: 393, stat: Journal Article,

Serotonergic modulation of dopamine measured with [11C]raclopride and PET in normal human subjects
Smith GS; Dewey SL; Brodie JD; Logan J; Vitkun SA; Simkowitz P; Schloesser R; Alexoff DA; Hurley A; Cooper T; Volkow ND
1997 Apr;154(4):490-496, American journal of psychiatry
— id: 12349, year: 1997, vol: 154, page: 490, stat: Journal Article,

Time-dependent effects of a haloperidol challenge on energy metabolism in the normal human brain
Bartlett EJ; Brodie JD; Simkowitz P; Dewey SL; Rusinek H; Volkow ND; Wolf AP; Smith G; Wolkin A; Cancro R
1996 Mar 29;60(2-3):91-99, Psychiatry research
— id: 12632, year: 1996, vol: 60, page: 91, stat: Journal Article,

Imaging for the clinical psychiatrist: facts, fantasies, and other musings
Brodie JD
1996 Feb;153(2):145-149, American journal of psychiatry
— id: 6892, year: 1996, vol: 153, page: 145, stat: Journal Article,

Two psychiatrists and their points of view imagery in psychiatry: Fact and reverie
Brodie, JD
1996 JUL-AUG ;5(289):114-116, La recherche
— id: 52867, year: 1996, vol: 5, page: 114, stat: Journal Article,

Opioid receptor imaging and displacement studies with [6-O-[11C] methyl]buprenorphine in baboon brain
Galynker, I; Schlyer, D J; Dewey, S L; Fowler, J S; Logan, J; Gatley, S J; MacGregor, R R; Ferrieri, R A; Holland, M J; Brodie, J; Simon, E; Wolf, A P
1996 Apr;23(3):325-331, Nuclear medicine & biology
— id: 76239, year: 1996, vol: 23, page: 325, stat: Journal Article,

The study of neurotransmitter interactions using positron emission tomography and functional coupling
Schloesser R; Simkowitz P; Bartlett EJ; Wolkin A; Smith GS; Dewey SL; Brodie JD
1996 Oct;19(5):371-389, Clinical neuropharmacology
— id: 12529, year: 1996, vol: 19, page: 371, stat: Journal Article,

Blunted change in cerebral glucose utilization after haloperidol treatment in schizophrenic patients with prominent negative symptoms
Wolkin A; Sanfilipo M; Duncan E; Angrist B; Wolf AP; Cooper TB; Brodie JD; Laska E; Rotrosen JP
1996 Mar;153(3):346-354, American journal of psychiatry
— id: 7060, year: 1996, vol: 153, page: 346, stat: Journal Article,

SEROTONERGIC MODULATION OF STRIATAL DOPAMINE MEASURED WITH POSITRON EMISSION TOMOGRAPHY (PET) AND IN-VIVO MICRODIALYSIS
DEWEY, SL; SMITH, GS; LOGAN, J; ALEXOFF, D; DING, YS; KING, P; PAPPAS, N; BRODIE, JD; ASHBY, CR
1995 JAN ;15(1):821-829, Journal of neuroscience
— id: 87461, year: 1995, vol: 15, page: 821, stat: Journal Article,

HUMAN SPECT STUDIES OF AMPHETAMINE-INDUCED CHANGE IN DOPAMINE ACTIVITY
SIMKOWITZ, P; BRODIE, JD; SMITH, GS; LANDSMAN, D; KRAMER, EL; SANGER, J; NOZ, M; BARTLETT, E; DEWEY, S; FRIEDHOFF, AJ
1995 MAY 1 ;37(9):598-598, Biological psychiatry
— id: 87282, year: 1995, vol: 37, page: 598, stat: Journal Article,

Haloperidol blocks the uptake of [18F]N-methylspiroperidol by extrastriatal dopamine receptors in schizophrenic patients
Yousef, K A; Volkow, N D; Schlyer, D J; Fowler, J S; Wolf, A P; Wang, G J; Smith, M R; Brodie, J D; Warner, D
1995 Jan;19(1):14-17, Synapse
— id: 107917, year: 1995, vol: 19, page: 14, stat: Journal Article,

Effects of haloperidol challenge on regional cerebral glucose utilization in normal human subjects
Bartlett EJ; Brodie JD; Simkowitz P; Dewey SL; Rusinek H; Wolf AP; Fowler JS; Volkow ND; Smith G; Wolkin A
1994 May;151(5):681-686, American journal of psychiatry
— id: 6319, year: 1994, vol: 151, page: 681, stat: Journal Article,

Diminished cerebral metabolic response to motor stimulation in schizophrenics: a PET study
Guenther, W; Brodie, J D; Bartlett, E J; Dewey, S L; Henn, F A; Volkow, N D; Alper, K; Wolkin, A; Cancro, R; Wolf, A P
1994 ;244(3):115-125, European archives of psychiatry & clinical neuroscience
— id: 76242, year: 1994, vol: 244, page: 115, stat: Journal Article,

THE SEROTONIN-DOPAMINE INTERACTION MEASURED WITH POSITRON EMISSION TOMOGRAPHY (PET) AND C-11 RACLOPRIDE IN NORMAL HUMAN-SUBJECTS
SMITH, GS; DEWEY, SL; LOGAN, J; BRODIE, JD; VITKUN, S; SIMKOWITZ, P; ALEXOFF, D; FOWLER, JS; VOLKOW, ND; WOLF, AP
1994 MAY ;35(5):P85-P85, Journal of nuclear medicine
— id: 52448, year: 1994, vol: 35, page: P85, stat: Journal Article,

Intersubject variability of brain glucose metabolic measurements in young normal males
Wang, G J; Volkow, N D; Wolf, A P; Brodie, J D; Hitzemann, R J
1994 Sep;35(9):1457-1466, Journal of nuclear medicine
— id: 144598, year: 1994, vol: 35, page: 1457, stat: Journal Article,

Acute d-amphetamine challenge in schizophrenia: effects on cerebral glucose utilization and clinical symptomatology
Wolkin A; Sanfilipo M; Angrist B; Duncan E; Wieland S; Wolf AP; Brodie JD; Cooper TB; Laska E; Rotrosen JP
1994 Sep 1;36(5):317-325, Biological psychiatry
— id: 8462, year: 1994, vol: 36, page: 317, stat: Journal Article,

Striatal binding of the PET ligand 11C-raclopride is altered by drugs that modify synaptic dopamine levels
Dewey SL; Smith GS; Logan J; Brodie JD; Fowler JS; Wolf AP
1993 Apr;13(4):350-356, Synapse
— id: 63165, year: 1993, vol: 13, page: 350, stat: Journal Article,

Modulation of central cholinergic activity by GABA and serotonin: PET studies with 11C-benztropine in primates
Dewey, S L; Smith, G S; Logan, J; Brodie, J D
1993 Jun;8(4):371-376, Neuropsychopharmacology
— id: 76267, year: 1993, vol: 8, page: 371, stat: Journal Article,

Effects of central cholinergic blockade on striatal dopamine release measured with positron emission tomography in normal human subjects
Dewey, S L; Smith, G S; Logan, J; Brodie, J D; Simkowitz, P; MacGregor, R R; Fowler, J S; Volkow, N D; Wolf, A P
1993 Dec 15;90(24):11816-11820, Proceedings of the National Academy of Sciences of the United States of America
— id: 76243, year: 1993, vol: 90, page: 11816, stat: Journal Article,

THE DOPAMINERGIC-CHOLINERGIC INTERACTION MEASURED WITH POSITRON EMISSION TOMOGRAPHY (PET) AND 11C-RACLOPRIDE IN NORMAL HUMAN-SUBJECTS
DEWEY, SL; SMITH, GS; LOGAN, J; SIMKOWITZ, P; BRODIE, JD; FOWLER, JS; VOLKOW, ND; WOLF, AP
1993 MAY ;34(5):P67-P67, Journal of nuclear medicine
— id: 54153, year: 1993, vol: 34, page: P67, stat: Journal Article,

3-DIMENSIONAL PET-PET BRAIN IMAGE REGISTRATION AND ENHANCEMENT OF THE SIGNAL-NOISE RATIO IN FUNCTIONAL PATTERNS - ANALYSIS OF FUNCTIONAL PATTERN ENHANCEMENT DURING A MOTOR TASK
LEVY, AV; BERTOLLO, D; DHAWAN, A; ARATA, L; BARTLETT, E; RUSINEK, H; VOLKOW, N; BRODIE, JD
1993 MAY ;34(5):P40-P40, Journal of nuclear medicine
— id: 73279, year: 1993, vol: 34, page: P40, stat: Journal Article,

ACUTE CEREBRAL METABOLIC RESPONSE TO HALOPERIDOL - BIOCHEMICAL AND BEHAVIORAL CORRELATIONS
SIMKOWITZ, P; BARTLETT, EJ; BRODIE, JD; CONVIT, A; WOLKIN, A; FRIEDHOFF, AJ; DEWEY, SL; WOLF, AP
1993 MAR 15 ;33(6A):A68-A68, Biological psychiatry
— id: 54173, year: 1993, vol: 33, page: A68, stat: Journal Article,

TEST-RETEST VARIABILITY OF TC-99M-HMPAO SPECT BRAIN PERFUSION STUDIES IN NORMAL HUMAN-SUBJECTS
SMITH, GS; MARTINO, J; KRAMER, EL; NOZ, M; SANGER, JJ; HEISIGER, E; JAFFAR, J; BRODIE, JD
1993 MAY ;34(5):P63-P64, Journal of nuclear medicine
— id: 54152, year: 1993, vol: 34, page: P63, stat: Journal Article,

GABAergic inhibition of endogenous dopamine release measured in vivo with 11C-raclopride and positron emission tomography
Dewey, S L; Smith, G S; Logan, J; Brodie, J D; Yu, D W; Ferrieri, R A; King, P T; MacGregor, R R; Martin, T P; Wolf, A P
1992 Oct;12(10):3773-3780, Journal of neuroscience
— id: 67825, year: 1992, vol: 12, page: 3773, stat: Journal Article,

The value of "the putrescine experience"
Fowler JS; Wolf AP; Volkow ND; Brodie JD; Hiesiger E
1992 Sep;33(9):1720-1721, Journal of nuclear medicine
— id: 61606, year: 1992, vol: 33, page: 1720, stat: Journal Article,

Is [1-11C]putrescine useful as a brain tumor marker? [see comments]
Hiesiger EM; Fowler JS; Logan J; Brodie JD; MacGregor RR; Christman DR; Wolf AP
1992 Feb;33(2):192-200, Journal of nuclear medicine
— id: 13698, year: 1992, vol: 33, page: 192, stat: Journal Article,

Spatial low frequency pattern analysis in positron emission tomography: a study between normals and schizophrenics
Levy, A V; Gomez-Mont, F; Volkow, N D; Corona, J F; Brodie, J D; Cancro, R
1992 Feb;33(2):287-295, Journal of nuclear medicine
— id: 144614, year: 1992, vol: 33, page: 287, stat: Journal Article,

Low cerebellar metabolism in medicated patients with chronic schizophrenia
Volkow, N D; Levy, A; Brodie, J D; Wolf, A P; Cancro, R; Van Gelder, P; Henn, F
1992 May;149(5):686-688, American journal of psychiatry
— id: 144613, year: 1992, vol: 149, page: 686, stat: Journal Article,

Negative symptoms and hypofrontality in chronic schizophrenia
Wolkin A; Sanfilipo M; Wolf AP; Angrist B; Brodie JD; Rotrosen J
1992 Dec;49(12):959-965, Archives of general psychiatry
— id: 57503, year: 1992, vol: 49, page: 959, stat: Journal Article,

Stability of resting deoxyglucose metabolic values in PET studies of schizophrenia
Bartlett EJ; Barouche F; Brodie JD; Wolkin A; Angrist B; Rotrosen J; Wolf AP
1991 May;40(1):11-20, Psychiatry research
— id: 14038, year: 1991, vol: 40, page: 11, stat: Journal Article,

Importance of pharmacologic control in PET studies: effects of thiothixene and haloperidol on cerebral glucose utilization in chronic schizophrenia
Bartlett EJ; Wolkin A; Brodie JD; Laska EM; Wolf AP; Sanfilipo M
1991 Oct;40(2):115-124, Psychiatry research
— id: 13887, year: 1991, vol: 40, page: 115, stat: Journal Article,

Amphetamine induced decreases in (18F)-N-methylspiroperidol binding in the baboon brain using positron emission tomography (PET)
Dewey, S L; Logan, J; Wolf, A P; Brodie, J D; Angrist, B; Fowler, J S; Volkow, N D
1991 Apr;7(4):324-327, Synapse
— id: 76236, year: 1991, vol: 7, page: 324, stat: Journal Article,

The spectral signature method for the analysis of PET brain images
Levy, A V; Laska, E; Brodie, J D; Volkow, N D; Wolf, A P
1991 Mar;11(2):A103-A113, Journal of cerebral blood flow & metabolism
— id: 140511, year: 1991, vol: 11, page: A103, stat: Journal Article,

THE EFFECT OF ENDOGENOUS DOPAMINE ON FLUORINE-18 N METHYLSPIROPERIDOL BINDING IS PREDICTED TO BE GREATER IN-VIVO THAN IN-VITRO
LOGAN J; DEWEY S L; WOLF A P; BRODIE J D; ANGRIST B; FOWLER J S; VOLKOW N D
1991 ;32(5 SUPPL):1071-1072, Journal of nuclear medicine
— id: 106732, year: 1991, vol: 32, page: 1071, stat: Journal Article,

Effects of endogenous dopamine on measures of [18F]N-methylspiroperidol binding in the basal ganglia: comparison of simulations and experimental results from PET studies in baboons
Logan, J; Dewey, S L; Wolf, A P; Fowler, J S; Brodie, J D; Angrist, B; Volkow, N D; Gatley, S J
1991 Nov;9(3):195-207, Synapse
— id: 76235, year: 1991, vol: 9, page: 195, stat: Journal Article,

Positron emission tomography: basic principles and applications in psychiatric research
Volkow, N D; Brodie, J; Bendriem, B
1991 ;620:128-144, Annals of the New York Academy of Sciences
— id: 144619, year: 1991, vol: 620, page: 128, stat: Journal Article,

Mapping muscarinic receptors in human and baboon brain using [N-11C-methyl]-benztropine
Dewey SL; MacGregor RR; Brodie JD; Bendriem B; King PT; Volkow ND; Schlyer DJ; Fowler JS; Wolf AP; Gatley SJ; et al.
1990 ;5(3):213-223, Synapse
— id: 62298, year: 1990, vol: 5, page: 213, stat: Journal Article,

Positron emission tomography (PET) studies of dopaminergic/cholinergic interactions in the baboon brain
Dewey, S L; Brodie, J D; Fowler, J S; MacGregor, R R; Schlyer, D J; King, P T; Alexoff, D L; Volkow, N D; Shiue, C Y; Wolf, A P
1990 ;6(4):321-327, Synapse
— id: 67824, year: 1990, vol: 6, page: 321, stat: Journal Article,

THE METABOLIC CENTROID METHOD FOR PET BRAIN IMAGE-ANALYSIS - REPLY
Levy, AV; Brodie, JD; Russell, JAG; Volkow, ND; Laska, EM; Wolf, AP
1990 May;10(3):439-440, Journal of cerebral blood flow & metabolism
— id: 31949, year: 1990, vol: 10, page: 439, stat: Journal Article,

D2-RECEPTOR OCCUPANCY AND PLASMA-CONCENTRATION OF ANTIPSYCHOTICS - RESPONSE
LOGAN, J; SCHLYER, DJ; WOLF, AP; FOWLER, JS; BRODIE, JD
1990 DEC 15 ;28(12):1068-1070, Biological psychiatry
— id: 51750, year: 1990, vol: 28, page: 1068, stat: Journal Article,

The metabolic centroid method for PET brain image analysis
Levy, A V; Brodie, J D; Russell, A G; Volkow, N D; Laska, E; Wolf, A P
1989 Jun;9(3):388-397, Journal of cerebral blood flow & metabolism
— id: 140512, year: 1989, vol: 9, page: 388, stat: Journal Article,

Dopamine blockade and clinical response: evidence for two biological subgroups of schizophrenia
Wolkin A; Barouche F; Wolf AP; Rotrosen J; Fowler JS; Shiue CY; Cooper TB; Brodie JD
1989 Jul;146(7):905-908, American journal of psychiatry
— id: 8395, year: 1989, vol: 146, page: 905, stat: Journal Article,

Dopamine receptor occupancy and plasma haloperidol levels
Wolkin A; Brodie JD; Barouche F; Rotrosen J; Wolf AP; Smith M; Fowler J; Cooper TB
1989 May;46(5):482-484, Archives of general psychiatry
— id: 23596, year: 1989, vol: 46, page: 482, stat: Journal Article,

Reproducibility of cerebral glucose metabolic measurements in resting human subjects
Bartlett EJ; Brodie JD; Wolf AP; Christman DR; Laska E; Meissner M
1988 Aug;8(4):502-512, Journal of cerebral blood flow & metabolism
— id: 11005, year: 1988, vol: 8, page: 502, stat: Journal Article,

Regional glucose metabolism in chronic schizophrenia
Brodie JD; Wolkin A; Wolf AP; Volkow N; Russell JA; Van Gelder P; Jaeger J; Fowler J; Rotrosen J; Cancro R
1988 ;3(1):54-54, American journal of physiologic imaging
— id: 11210, year: 1988, vol: 3, page: 54, stat: Journal Article,

DIFFICULTIES IN DIFFERENTIATING RECURRENT TUMOR FROM TREATMENT RELATED NECROSIS BY POSITRON EMISSION TOMOGRAPHY SCANNING WITH [11C]2-DEOXY-D-GLUCOSE - THE ISSUE OF MIXED LESIONS
HIESIGER, EM; BUDZILOVICH, G; LOGAN, J; FOWLER, JS; BRODIE, JD; WOLF, AP; MACGREGOR, RR; CHRISTMAN, DR; FLAMM, E
1988 MAR ;29(4):171-171, Proceedings (American Association for Cancer Research)
— id: 41772, year: 1988, vol: 29, page: 171, stat: Journal Article,

Serial [18F]N-methylspiroperidol PET studies to measure changes in antipsychotic drug D-2 receptor occupancy in schizophrenic patients
Smith M; Wolf AP; Brodie JD; Arnett CD; Barouche F; Shiue CY; Fowler JS; Russell JA; MacGregor RR; Wolkin A; et al.
1988 Apr 1;23(7):653-663, Biological psychiatry
— id: 62153, year: 1988, vol: 23, page: 653, stat: Journal Article,

Brain interactions in chronic schizophrenics under resting and activation conditions
Volkow, N D; Wolf, A P; Brodie, J D; Cancro, R; Overall, J E; Rhoades, H; Van Gelder, P
1988 Jan-Feb;1(1):47-53, Schizophrenia research
— id: 144634, year: 1988, vol: 1, page: 47, stat: Journal Article,

Brain interactions in chronic schizophrenics under resting and activation conditions
Volkow, ND; Wolf, AP; Brodie, JD; Cancro, R; Overall, JE; Rhoades, H; Van, Gelder, P
1988 ;1(4):309-, Schizophrenia research
— id: 584852, year: 1988, vol: 1, page: 309, stat: Journal Article,

Low frontal glucose utilization in chronic schizophrenia: a replication study
Wolkin A; Angrist B; Wolf A; Brodie JD; Wolkin B; Jaeger J; Cancro R; Rotrosen J
1988 Feb;145(2):251-253, American journal of psychiatry
— id: 11197, year: 1988, vol: 145, page: 251, stat: Journal Article,

Correlations between glucose metabolic rates in brain regions of healthy male adults at rest and during language stimulation
Bartlett EJ; Brown JW; Wolf AP; Brodie JD
1987 Sep;32(1):1-18, Brain & language
— id: 11376, year: 1987, vol: 32, page: 1, stat: Journal Article,

PET STUDIES IN SCHIZOPHRENIA
Brodie, JD; Wolf, AP; Bartlett, E; Wolkin, A; Vangelder, P; Volkow, N
1987 Apr;32(1-2):788-788, International journal of neuroscience
— id: 31395, year: 1987, vol: 32, page: 788, stat: Journal Article,

PET STUDIES IN SCHIZOPHRENIA
Brodie, JD; Wolf, AP; Wolkin, A; Arnett, CD; Angrist, B; Fowler, J; Smith, M; Russell, J; Logan, J; Christman, D; Rotrosen, J; Volkow, N
1987 Apr;32(1-2):445-445, International journal of neuroscience
— id: 31391, year: 1987, vol: 32, page: 445, stat: Journal Article,

Positron emission tomography studies of normal aging: a replication of PET III and 18-FDG using PET VI and 11-CDG
de Leon MJ; George AE; Tomanelli J; Christman D; Kluger A; Miller J; Ferris SH; Fowler J; Brodie JD; van Gelder P; et al
1987 Jul-Aug;8(4):319-323, Neurobiology of aging
— id: 9473, year: 1987, vol: 8, page: 319, stat: Journal Article,

Serial PET studies of human cerebral malignancy with [1-11C]putrescine and [1-11C]2-deoxy-D-glucose
Hiesiger E; Fowler JS; Wolf AP; Logan J; Brodie JD; McPherson D; MacGregor RR; Christman DR; Volkow ND; Flamm E
1987 Aug;28(8):1251-1261, Journal of nuclear medicine
— id: 61607, year: 1987, vol: 28, page: 1251, stat: Journal Article,

Phenomenological correlates of metabolic activity in 18 patients with chronic schizophrenia
Volkow, N D; Wolf, A P; Van Gelder, P; Brodie, J D; Overall, J E; Cancro, R; Gomez-Mont, F
1987 Feb;144(2):151-158, American journal of psychiatry
— id: 144637, year: 1987, vol: 144, page: 151, stat: Journal Article,

Effects of amphetamine on local cerebral metabolism in normal and schizophrenic subjects as determined by positron emission tomography
Wolkin A; Angrist B; Wolf A; Brodie J; Wolkin B; Jaeger J; Cancro R; Rotrosen J
1987 ;92(2):241-246, Psychopharmacology
— id: 23614, year: 1987, vol: 92, page: 241, stat: Journal Article,

EFFECTS OF AMPHETAMINE ON LOCAL CEREBRAL METABOLISM IN NORMAL AND SCHIZOPHRENIC SUBJECTS AS DETERMINED BY POSITRON EMISSION TOMOGRAPHY USING [C-11-1] 2-DEOXY-D-GLUCOSE (C-11-2DG)
BRODIE, JD; WOLKIN, A; ANGRIST, B; WOLF, AP; JORDAN, B; JAEGER, J; CANCRO, R; ROTROSEN, J
1986 JUN ;27(6):901-901, Journal of nuclear medicine
— id: 41433, year: 1986, vol: 27, page: 901, stat: Journal Article,

Putrescine metabolism in human brain tumors
Goldman, S S; Volkow, N D; Brodie, J; Flamm, E S
1986 ;4(1):23-29, Journal of neuro-oncology
— id: 123879, year: 1986, vol: 4, page: 23, stat: Journal Article,

SERIAL PET STUDIES OF HUMAN CEREBRAL MALIGNANCY WITH [1-C-11] PUTRESCINE (C-11-PUT) AND [1-C-11]2-DEOXY-D-GLUCOSE (C-11-2DG)
HIESIGER, E; LOGAN, J; WOLF, AP; BRODIE, JD; MCPHERSON, D; MACGREGOR, RR; FOWLER, JS; CHRISTMAN, DR; FLAMM, E
1986 JUN ;27(6):889-889, Journal of nuclear medicine
— id: 41432, year: 1986, vol: 27, page: 889, stat: Journal Article,

IMAGING OF HUMAN-BRAIN TUMORS BY POSITRON EMISSION TOMOGRAPHY (PET) USING (1-C-11) PUTRESCINE (C-11-PU) AND (1-C-11)-2-DEOXY-D-GLUCOSE (C-11-2DG)
HIESIGER, EM; FOWLER, J; BRODIE, JD; LOGAN, L; MACGREGOR, R; CHRISTMAN, D; FLAMM, EJ; WOLF, AP
1986 MAR ;27(2):155-155, Proceedings (American Association for Cancer Research)
— id: 41427, year: 1986, vol: 27, page: 155, stat: Journal Article,

SERIAL [F-18] N-METHYLSPIROPERIDOL (F-18 NMS) PET STUDIES MEASURE CHANGES IN ANTIPSYCHOTIC DRUG D2 RECEPTOR OCCUPANCY IN SCHIZOPHRENICS
SMITH, M; WOLF, AP; SHIUE, CY; FOWLER, JS; RUSSELL, JAG; MACGREGOR, R; ARNETT, C; LOGAN, J; WOLKIN, A; ROTROSEN, J; BRODIE, JD
1986 JUN ;27(6):880-880, Journal of nuclear medicine
— id: 41431, year: 1986, vol: 27, page: 880, stat: Journal Article,

Brain metabolism in patients with schizophrenia before and after acute neuroleptic administration
Volkow, N D; Brodie, J D; Wolf, A P; Angrist, B; Russell, J; Cancro, R
1986 Oct;49(10):1199-1202, Journal of neurology neurosurgery & psychiatry
— id: 106693, year: 1986, vol: 49, page: 1199, stat: Journal Article,

Brain organization in schizophrenia
Volkow, N D; Brodie, J D; Wolf, A P; Gomez-Mont, F; Cancro, R; Van Gelder, P; Russell, J A; Overall, J
1986 Aug;6(4):441-446, Journal of cerebral blood flow & metabolism
— id: 144640, year: 1986, vol: 6, page: 441, stat: Journal Article,

SYNTHESIS AND BIODISTRIBUTION OF NO-CARRIER-ADDED [1-11C PUTRESCINE
MCPHERSON, DW; FOWLER, JS; WOLF, AP; ARNETT, CD; BRODIE, JD; VOLKOW, N
1985 ;26(10):1186-1189, Journal of nuclear medicine
— id: 41143, year: 1985, vol: 26, page: 1186, stat: Journal Article,

SYNTHESIS AND BIODISTRIBUTION OF NO-CARRIER-ADDED [1-C-11] PUTRESCINE
Mcpherson, DW; Fowler, JS; Wolf, AP; Arnett, CD; Brodie, JD; Volkow, N
1985 ;26(5):P127-P128, Journal of nuclear medicine
— id: 30742, year: 1985, vol: 26, page: P127, stat: Journal Article,

Persistence of cerebral metabolic abnormalities in chronic schizophrenia as determined by positron emission tomography
Wolkin A; Jaeger J; Brodie JD; Wolf AP; Fowler J; Rotrosen J; Gomez-Mont F; Cancro R
1985 May;142(5):564-571, American journal of psychiatry
— id: 23625, year: 1985, vol: 142, page: 564, stat: Journal Article,

Patterns of metabolic activity in the treatment of schizophrenia
Brodie JD; Christman DR; Corona JF; Fowler JS; Gomez-Mont F; Jaeger J; Micheels PA; Rotrosen J; Russell JA; Volkow ND; et al.
1984 ;15 Suppl(3-4):S166-S169, Annals of neurology
— id: 23635, year: 1984, vol: 15 Suppl, page: S166, stat: Journal Article,

REGIONAL GLUCOSE-METABOLISM IN CHRONIC-SCHIZOPHRENIA
Brodie, JD; Wolkin, A; Wolfe, AP; Jaeger, J; Fowler, J; Rotrosen, J; Cancro, R
1984 ;2(3):226-226, International journal of psychophysiology
— id: 30978, year: 1984, vol: 2, page: 226, stat: Journal Article,

Positron emission tomography and computed tomography assessments of the aging human brain
de Leon MJ; George AE; Ferris SH; Christman DR; Fowler JS; Gentes CI; Brodie J; Reisberg B; Wolf AP
1984 Feb;8(1):88-94, Journal of computer assisted tomography
— id: 9482, year: 1984, vol: 8, page: 88, stat: Journal Article,

Regional brain glucose metabolism in chronic schizophrenia. A positron emission transaxial tomographic study
Farkas, T; Wolf, A P; Jaeger, J; Brodie, J D; Christman, D R; Fowler, J S
1984 Mar;41(3):293-300, Archives of general psychiatry
— id: 323812, year: 1984, vol: 41, page: 293, stat: Journal Article,

REGIONAL BRAIN GLUCOSE-METABOLISM IN CHRONIC-SCHIZOPHRENIA - A POSITRON EMISSION TRANSAXIAL TOMOGRAPHIC STUDY
FARKAS, T; WOLF, AP; JAEGER, J; BRODIE, JD; CHRISTMAN, DR; FOWLER, JS; MACGREGOR, RR; DELEON, MJ; DEFINA, P; GOLDMAN, A; YONEKURA, Y; BRILL, AB; SCHWARTZ, M; LOGAN, J; CANCRO, R
1984 ;41(3):293-300, Archives of general psychiatry
— id: 41102, year: 1984, vol: 41, page: 293, stat: Journal Article,

Positron emission tomographic studies of aging and Alzheimer disease
de Leon MJ; Ferris SH; George AE; Christman DR; Fowler JS; Gentes C; Reisberg B; Gee B; Emmerich M; Yonekura Y; Brodie J; Kricheff II; Wolf AP
1983 May-Jun;4(3):568-571, AJNR. American journal of neuroradiology
— id: 9486, year: 1983, vol: 4, page: 568, stat: Journal Article,

Labeled putrescine as a probe in brain tumors
Volkow, N; Goldman, S S; Flamm, E S; Cravioto, H; Wolf, A P; Brodie, J D
1983 Aug 12;221(4611):673-675, Science
— id: 118098, year: 1983, vol: 221, page: 673, stat: Journal Article,

Margaret B : a "typical" Bellevue case
Brodie JD; Rohrs CC
1978 ;15:35-43, Psychiatric opinion
— id: 105407, year: 1978, vol: 15, page: 35, stat: Journal Article,

Mechanism and prevention of tachyphylaxis and cyanide toxicosis after nitroprusside-induced hypotension
Cottrell JE; Casthely P; Brodie JD; Patel K; Klein A; Turndorf H
1978 ;29:308-310, Surgical forum
— id: 11456, year: 1978, vol: 29, page: 308, stat: Journal Article,

Prevention of nitroprusside-induced cyanide toxicity with hydroxocobalamin
Cottrell JE; Casthely P; Brodie JD; Patel K; Klein A; Turndorf H
1978 May 13;298(15):809-811, New England journal of medicine
— id: 45859, year: 1978, vol: 298, page: 809, stat: Journal Article,

PREVENTION OF CYANIDE INTOXICATION FOLLOWING SODIUM NITROPRUSSIDE INDUCED HYPOTENSION
Cottrell, JE; Casthely, P; Brodie, JD; Patel, K; Klein, A; Turndorf, H
1978 ;6(2):108-108, Critical care medicine
— id: 29851, year: 1978, vol: 6, page: 108, stat: Journal Article,

Cleavage of coenzyme B 12 by methylmalonyl coenzyme A mutase
Babior, B M; Woodams, A D; Brodie, J D
1973 Feb 25;248(4):1445-1450, Journal of biological chemistry
— id: 132253, year: 1973, vol: 248, page: 1445, stat: Journal Article,

FAST AND SLOW INHIBITORS OF OX HEART SUCCINATE DEHYDROGENASE ACTION OF OXAL ACETATE AND ITS FLUORO ANALOGUES
KAPPEN L S; BRODIE J D; NICHOLLS P
1973 ;1(4):877-880, Transactions (Biochemical Society (Great Britain))
— id: 105406, year: 1973, vol: 1, page: 877, stat: Journal Article,

Subcellular distribution of methylmalonyl CoA carbonylmutase in human liver extracts
Morrow, G 3rd; Brodie, J D; Strimpler, A; Barness, L A
1973 Oct;8(2):240-248, Biochemical medicine
— id: 156159, year: 1973, vol: 8, page: 240, stat: Journal Article,

Proton magnetic resonance of vitamin B 12 derivatives. Functioning of B 12 coenzymes
Brodie, J D; Poe, M
1972 Jun;11(13):2534-2542, Biochemistry
— id: 156160, year: 1972, vol: 11, page: 2534, stat: Journal Article,

Proton magnetic resonance studies of vitamin B12. Proton magnetic resonance spectra of some cobalamins and cobinamides
Brodie, J D; Poe, M
1971 Mar;10(5):914-922, Biochemistry
— id: 159045, year: 1971, vol: 10, page: 914, stat: Journal Article,

Mechanism of mammalian cobalamin-dependent methionine biosynthesis
Burke, G T; Mangum, J H; Brodie, J D
1971 Aug 3;10(16):3079-3085, Biochemistry
— id: 132255, year: 1971, vol: 10, page: 3079, stat: Journal Article,

Metabolism and enzymology of fluorosuccinic acids. I. Interactions with the succinate oxidase system
Brodie, J D; Nicholls, P
1970 Mar;198(3):423-437, Biochimica & biophysica acta
— id: 156162, year: 1970, vol: 198, page: 423, stat: Journal Article,

Methylcobalamin as an intermediate in mammalian methionine biosynthesis
Burke, G T; Mangum, J H; Brodie, J D
1970 Oct;9(22):4297-4302, Biochemistry
— id: 156163, year: 1970, vol: 9, page: 4297, stat: Journal Article,

Metabolism and enzymology of flurosuccinic acids. II. Substrate and inhibitor effects with soluble succinate dehydrogenase
Tober, C L; Nicholls, P; Brodie, J D
1970 Jun;138(2):506-514, Archives of biochemistry & biophysics. ABB
— id: 132256, year: 1970, vol: 138, page: 506, stat: Journal Article,

On the mechanism of catalysis by vitamin B12
Brodie, J D
1969 Feb;62(2):461-467, Proceedings of the National Academy of Sciences of the United States of America
— id: 156161, year: 1969, vol: 62, page: 461, stat: Journal Article,

Enzymatic and metabolic behavior of fluorosuccinic acids
Brodie, J D; Nicholls, P
1968 Sep;32(6):1071-1077, Biochemical & biophysical research communications
— id: 156164, year: 1968, vol: 32, page: 1071, stat: Journal Article,

Origin of photolabile methyl groups in methionine biosynthesis
Brodie, J D
1967 Feb;26(3):261-264, Biochemical & biophysical research communications
— id: 156165, year: 1967, vol: 26, page: 261, stat: Journal Article,

Interrelationship of adenosyl methionine and methyl-B12 in the biosynthesis of methionine
Kerwar, S S; Mangum, J H; Scrimgeour, K G; Brodie, J D; Huennekens, F M
1966 Sep 26;116(1):305-318, Archives of biochemistry & biophysics. ABB
— id: 132257, year: 1966, vol: 116, page: 305, stat: Journal Article,

ENZYME-BOUND INTERMEDIATES IN THE BIOSYNTHESIS OF MEVALONIC AND PALMITIC AICDS
BRODIE, J D; WASSON, G; PORTER, J W
1964 May;239:1346-1356, Journal of biological chemistry
— id: 156158, year: 1964, vol: 239, page: 1346, stat: Journal Article,

The formation of malonyl-enzyme and its conversion to fatty acids and beta-hydroxy, beta-methyl glutaryl coenzyme A
BRODIE, J D; WASSON, G W; PORTER, J W
1963 Jul;12:27-33, Biochemical & biophysical research communications
— id: 156157, year: 1963, vol: 12, page: 27, stat: Journal Article,

The participation of malonyl coenzyme A in the biosynthesis of mevalonic acid
BRODIE, J D; WASSON, G; PORTER, J W
1963 Apr;238:1294-1301, Journal of biological chemistry
— id: 156156, year: 1963, vol: 238, page: 1294, stat: Journal Article,

MALONYL COA - A NEW INTERMEDIATE IN FORMATION OF MEVALONIC ACID
BRODIE, JD; PORTER, JW; WASSON, GW
1962 ;8(1-2):76-&, Biochemical & biophysical research communications
— id: 105404, year: 1962, vol: 8, page: 76, stat: Journal Article,

STUDIES ON A MEVALDIC ACID REDUCTASE OF RAT LIVER
KNAUSS, HJ; BRODIE, JD; PORTER, JW
1962 ;3(2):197-&, Journal of lipid research
— id: 105403, year: 1962, vol: 3, page: 197, stat: Journal Article,

The synthesis of mevalonic acid by non-particulate avian and mammalian enzyme systems
BRODIE, J; PORTER, J W
1960 Aug;3:173-177, Biochemical & biophysical research communications
— id: 630142, year: 1960, vol: 3, page: 173, stat: Journal Article,