Kenneth D. Brandt, M.D.

A 2-year randomised, double-blind, placebo-controlled, multicentre study of oral selective iNOS inhibitor, cindunistat (SD-6010), in patients with symptomatic osteoarthritis of the knee
Hellio le Graverand, Marie-Pierre; Clemmer, Ray S; Redifer, Patricia; Brunell, Robert M; Hayes, Curtis W; Brandt, Kenneth D; Abramson, Steven B; Manning, Pamela T; Miller, Colin G; Vignon, Eric
2013 Feb;72(2):187-195, Annals of rheumatic diseases
— id: 217372, year: 2013, vol: 72, page: 187, stat: Journal Article,

A 2-year randomized, double-blind, placebo-controlled, multicenter study of an oral selective iNOS inhibitor in subjects with symptomatic osteoarthritis of the knee
Hellio, Le Graverand-Gastineau M -P; Clemmer, R; Redifer, P; Brunell, R M; Hayes, C W; Brandt, K; Abramson, S B; Manning, P T; Miller, C G; Vignon, E
2012 April 2012;20:S38-S38, Osteoarthritis & cartilage
— id: 169271, year: 2012, vol: 20, page: S38, stat: Journal Article,

Why should we expect a structure-modifying osteoarthritis drug to relieve osteoarthritis pain?
Brandt, Kenneth D
2011 Jul;70(7):1175-1177, Annals of rheumatic diseases
— id: 142147, year: 2011, vol: 70, page: 1175, stat: Journal Article,

Malalignment and subchondral bone turnover in contralateral knees of overweight/obese women with unilateral osteoarthritis: Implications for bilateral disease
Mazzuca, Steven A; Brandt, Kenneth D; Lane, Kathleen A; Chakr, Rafael
2011 Nov;63(11):1528-1534, Arthritis care & research (2010)
— id: 142150, year: 2011, vol: 63, page: 1528, stat: Journal Article,

Etiopathogenesis of osteoarthritis
Brandt, Kenneth D; Dieppe, Paul; Radin, Eric
2009 Jan;93(1):88-96, Medical clinics of North America
— id: 142134, year: 2009, vol: 93, page: 88, stat: Journal Article,

Commentary: is it useful to subset "primary" osteoarthritis? A critique based on evidence regarding the etiopathogenesis of osteoarthritis
Brandt, Kenneth D; Dieppe, Paul; Radin, Eric L
2009 Oct;39(2):81-95, Seminars in arthritis & rheumatism
— id: 142137, year: 2009, vol: 39, page: 81, stat: Journal Article,

Methodology and statistical analysis in the Glucosamine/Chondroitin Arthritis Intervention Trial: comment on the article by Sawitzke et al
Brandt, Kenneth D; Mazzuca, Steven A; Katz, Barry P
2009 Nov;60(11):3514-5; author reply 3515, Arthritis & rheumatism
— id: 142139, year: 2009, vol: 60, page: 3514, stat: Journal Article,

Etiopathogenesis of osteoarthritis
Brandt, Kenneth D; Dieppe, Paul; Radin, Eric L
2008 Aug;34(3):531-559, Rheumatic diseases clinics of North America
— id: 142133, year: 2008, vol: 34, page: 531, stat: Journal Article,

Risk factors for early radiographic changes of tibiofemoral osteoarthritis
Mazzuca, Steven A; Brandt, Kenneth D; Katz, Barry P; Ding, Yan; Lane, Kathleen A; Buckwalter, Kenneth A
2007 Mar;66(3):394-399, Annals of rheumatic diseases
— id: 142125, year: 2007, vol: 66, page: 394, stat: Journal Article,

Urinary TIINE concentrations in a randomized controlled trial of doxycycline in knee osteoarthritis: implications of the lack of association between TIINE levels and joint space narrowing
Otterness, Ivan G; Brandt, Kenneth D; Le Graverand, Marie-Pierre Hellio; Mazzuca, Steven A
2007 Nov;56(11):3644-3649, Arthritis & rheumatism
— id: 142131, year: 2007, vol: 56, page: 3644, stat: Journal Article,

Studies in animal models of osteoarthritis as predictors of a structure-modifying effect of diacerhein in humans with osteoarthritis
Brandt, Kenneth D
2006 ;43(3-4):589-594, Biorheology
— id: 142123, year: 2006, vol: 43, page: 589, stat: Journal Article,

Experience with a placebo-controlled randomized clinical trial of a disease-modifying drug for osteoarthritis: the doxycycline trial
Brandt, Kenneth D; Mazzuca, Steven A
2006 Feb;32(1):795-808, Rheumatic diseases clinics of North America
— id: 142116, year: 2006, vol: 32, page: 795, stat: Journal Article,

The randomized clinical trial of doxycycline in knee osteoarthritis: comment on the editorial by Dieppe
Brandt, Kenneth D; Mazzuca, Steven A
2006 Feb;54(2):684-684, Arthritis & rheumatism
— id: 142114, year: 2006, vol: 54, page: 684, stat: Journal Article,

Acetaminophen, like conventional NSAIDs, may reduce synovitis in osteoarthritic knees
Brandt, Kenneth D; Mazzuca, Steven A; Buckwalter, Kenneth A
2006 Nov;45(11):1389-1394, Rheumatology (Oxford)
— id: 142117, year: 2006, vol: 45, page: 1389, stat: Journal Article,

Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis
Clegg, Daniel O; Reda, Domenic J; Harris, Crystal L; Klein, Marguerite A; O'Dell, James R; Hooper, Michele M; Bradley, John D; Bingham, Clifton O 3rd; Weisman, Michael H; Jackson, Christopher G; Lane, Nancy E; Cush, John J; Moreland, Larry W; Schumacher, H Ralph Jr; Oddis, Chester V; Wolfe, Frederick; Molitor, Jerry A; Yocum, David E; Schnitzer, Thomas J; Furst, Daniel E; Sawitzke, Allen D; Shi, Helen; Brandt, Kenneth D; Moskowitz, Roland W; Williams, H James
2006 Feb 23;354(8):795-808, New England journal of medicine
— id: 142115, year: 2006, vol: 354, page: 795, stat: Journal Article,

Associations between joint space narrowing and molecular markers of collagen and proteoglycan turnover in patients with knee osteoarthritis
Mazzuca, Steven A; Poole, A Robin; Brandt, Kenneth D; Katz, Barry P; Lane, Kathleen A; Lobanok, Tatiana
2006 Jun;33(6):1147-1151, Journal of rheumatology
— id: 142119, year: 2006, vol: 33, page: 1147, stat: Journal Article,

Effects of strength training on the incidence and progression of knee osteoarthritis
Mikesky, Alan E; Mazzuca, Steven A; Brandt, Kenneth D; Perkins, Susan M; Damush, Teresa; Lane, Kathleen A
2006 Oct 15;55(5):690-699, Arthritis & rheumatism
— id: 142126, year: 2006, vol: 55, page: 690, stat: Journal Article,

Translating osteoarthritis into numbers: the importance of alignment in knee radiography for clinical trials of structure-modifying drugs
Brandt, Kenneth D
2005 May;52(5):1343-1345, Arthritis & rheumatism
— id: 142107, year: 2005, vol: 52, page: 1343, stat: Journal Article,

Lessons learned from nine clinical trials of disease-modifying osteoarthritis drugs
Brandt, Kenneth D; Mazzuca, Steven A
2005 Nov;52(11):3349-3359, Arthritis & rheumatism
— id: 142112, year: 2005, vol: 52, page: 3349, stat: Journal Article,

Effects of doxycycline on progression of osteoarthritis: results of a randomized, placebo-controlled, double-blind trial
Brandt, Kenneth D; Mazzuca, Steven A; Katz, Barry P; Lane, Kathleen A; Buckwalter, Kenneth A; Yocum, David E; Wolfe, Frederick; Schnitzer, Thomas J; Moreland, Larry W; Manzi, Susan; Bradley, John D; Sharma, Leena; Oddis, Chester V; Hugenberg, Steven T; Heck, Louis W
2005 Jul;52(7):2015-2025, Arthritis & rheumatism
— id: 142109, year: 2005, vol: 52, page: 2015, stat: Journal Article,

Use of the plasma stromelysin (matrix metalloproteinase 3) concentration to predict joint space narrowing in knee osteoarthritis
Lohmander, L Stefan; Brandt, Kenneth D; Mazzuca, Steven A; Katz, Barry P; Larsson, Staffan; Struglics, Andre; Lane, Kathleen A
2005 Oct;52(10):3160-3167, Arthritis & rheumatism
— id: 142111, year: 2005, vol: 52, page: 3160, stat: Journal Article,

Severity of joint pain and Kellgren-Lawrence grade at baseline are better predictors of joint space narrowing than bone scintigraphy in obese women with knee osteoarthritis
Mazzuca, Steven A; Brandt, Kenneth D; Schauwecker, Donald S; Katz, Barry P; Meyer, Joan M; Lane, Kathleen A; Bradley, John D; Hugenberg, Steven T; Wolfe, Frederick; Moreland, Larry W; Heck, Louis W; Yocum, David E; Schnitzer, Thomas J; Sharma, Leena; Manzi, Susan; Oddis, Chester V
2005 Aug;32(8):1540-1546, Journal of rheumatology
— id: 142110, year: 2005, vol: 32, page: 1540, stat: Journal Article,

Effect of intraarticular hyaluronan injection on vertical ground reaction force and progression of osteoarthritis after anterior cruciate ligament transection
Smith, Gerald Jr; Myers, Stephen L; Brandt, Kenneth D; Mickler, Elizabeth A; Albrecht, Marjorie E
2005 Feb;32(2):325-334, Journal of rheumatology
— id: 142105, year: 2005, vol: 32, page: 325, stat: Journal Article,

Neuromuscular aspects of osteoarthritis: a perspective
Brandt, Kenneth D
2004 ;260:169-172, Novartis foundation symposium
— id: 142098, year: 2004, vol: 260, page: 169, stat: Journal Article,

Hyaluronan injection affects neither osteoarthritis progression nor loading of the OA knee in dogs
Brandt, Kenneth D; Smith, Gerald N; Myers, Stephen L
2004 ;41(3-4):493-502, Biorheology
— id: 142099, year: 2004, vol: 41, page: 493, stat: Journal Article,

Can a Nurse-Directed Intervention Reduce the Exposure of Patients With Knee Osteoarthritis to Nonsteroidal Antiinflammatory Drugs?
Mazzuca SA; Brandt KD; Katz BP; Ragozzino LR; G'sell PM
2004 Dec;10(6):315-322, Journal of clinical rheumatology. JCR
— id: 142127, year: 2004, vol: 10, page: 315, stat: Journal Article,

Pitfalls in the accurate measurement of joint space narrowing in semiflexed, anteroposterior radiographic imaging of the knee
Mazzuca, Steven A; Brandt, Kenneth D; Buckwalter, Kenneth A; Lequesne, Michel
2004 Aug;50(8):2508-2515, Arthritis & rheumatism
— id: 142100, year: 2004, vol: 50, page: 2508, stat: Journal Article,

Subject retention and adherence in a randomized placebo-controlled trial of a disease-modifying osteoarthritis drug
Mazzuca, Steven A; Brandt, Kenneth D; Katz, Barry P; Lane, Kathleen A; Bradley, John D; Heck, Louis W; Hugenberg, Steven T; Manzi, Susan; Moreland, Larry W; Oddis, Chester V; Schnitzer, Thomas J; Sharma, Leena; Wolfe, Frederick; Yocum, David E
2004 Dec 15;51(6):933-940, Arthritis & rheumatism
— id: 142104, year: 2004, vol: 51, page: 933, stat: Journal Article,

Bone scintigraphy is not a better predictor of progression of knee osteoarthritis than Kellgren and Lawrence grade
Mazzuca, Steven A; Brandt, Kenneth D; Schauwecker, Donald S; Buckwalter, Kenneth A; Katz, Barry P; Meyer, Joan M; Lane, Kathleen A
2004 Feb;31(2):329-332, Journal of rheumatology
— id: 142095, year: 2004, vol: 31, page: 329, stat: Journal Article,

Pilot study of the effects of a heat-retaining knee sleeve on joint pain, stiffness, and function in patients with knee osteoarthritis
Mazzuca, Steven A; Page, Mark C; Meldrum, Russell D; Brandt, Kenneth D; Petty-Saphon, Satham
2004 Oct 15;51(5):716-721, Arthritis & rheumatism
— id: 142102, year: 2004, vol: 51, page: 716, stat: Journal Article,

[Paracetamol in the treatment of osteoarthritis pain]
Brandt, Kenneth
2003 ;63 Spec No 2:23-41, Drugs
— id: 142094, year: 2003, vol: 63 Spec No 2, page: 23, stat: Journal Article,

Is a strong quadriceps muscle bad for a patient with knee osteoarthritis?
Brandt, Kenneth D
2003 Apr 15;138(8):678-679, Annals of internal medicine
— id: 142086, year: 2003, vol: 138, page: 678, stat: Journal Article,

Osteoarthritis. Preface
Brandt, Kenneth D
2003 Nov;29(4):ix-xiii, Rheumatic diseases clinics of North America
— id: 142089, year: 2003, vol: 29, page: ix, stat: Journal Article,

Response of joint structures to inactivity and to reloading after immobilization
Brandt, Kenneth D
2003 Apr 15;49(2):267-271, Arthritis & rheumatism
— id: 142084, year: 2003, vol: 49, page: 267, stat: Journal Article,

Work Group recommendations: 2002 Exercise and Physical Activity Conference, St Louis, Missouri
Chang, Rowland; Roubenoff, Ronenn; Mayer, Jean; Brandt, Kenneth D; Schanberg, Laura E
2003 Apr 15;49(2):280-280, Arthritis & rheumatism
— id: 142085, year: 2003, vol: 49, page: 280, stat: Journal Article,

What is important in treating osteoarthritis? Whom should we treat and how should we treat them?
Dieppe, Paul; Brandt, Kenneth D
2003 Nov;29(4):687-716, Rheumatic diseases clinics of North America
— id: 142090, year: 2003, vol: 29, page: 687, stat: Journal Article,

Is knee radiography useful for studying the efficacy of a disease-modifying osteoarthritis drug in humans?
Mazzuca, Steven A; Brandt, Kenneth D
2003 Nov;29(4):819-830, Rheumatic diseases clinics of North America
— id: 142091, year: 2003, vol: 29, page: 819, stat: Journal Article,

Detection of radiographic joint space narrowing in subjects with knee osteoarthritis: longitudinal comparison of the metatarsophalangeal and semiflexed anteroposterior views
Mazzuca, Steven A; Brandt, Kenneth D; Buckwalter, Kenneth A
2003 Feb;48(2):385-390, Arthritis & rheumatism
— id: 142083, year: 2003, vol: 48, page: 385, stat: Journal Article,

Measurement of radiographic joint space width in the tibiofemoral compartment of the osteoarthritic knee: comparison of standing anteroposterior and Lyon schuss views
Vignon, Eric; Piperno, Muriel; Le Graverand, Marie-Pierre Hellio; Mazzuca, Steven A; Brandt, Kenneth D; Mathieu, Pierre; Favret, Huguett; Vignon, Martine; Merle-Vincent, Florence; Conrozier, Thierry
2003 Feb;48(2):378-384, Arthritis & rheumatism
— id: 142082, year: 2003, vol: 48, page: 378, stat: Journal Article,

Tidal irrigation as treatment for knee osteoarthritis: a sham-controlled, randomized, double-blinded evaluation
Bradley, John D; Heilman, Douglas K; Katz, Barry P; Gsell, Patricia; Wallick, Janine E; Brandt, Kenneth D
2002 Jan;46(1):100-108, Arthritis & rheumatism
— id: 142073, year: 2002, vol: 46, page: 100, stat: Journal Article,

Animal models of osteoarthritis
Brandt, Kenneth D
2002 ;39(1-2):221-235, Biorheology
— id: 142078, year: 2002, vol: 39, page: 221, stat: Journal Article,

Simple analgesics versus NSAID
Brandt, Kenneth D
2002 Mar;29(3):640-642, Journal of rheumatology
— id: 142075, year: 2002, vol: 29, page: 640, stat: Journal Article,

Which is the best radiographic protocol for a clinical trial of a structure modifying drug in patients with knee osteoarthritis?
Brandt, Kenneth D; Mazzuca, Steven A; Conrozier, Thierry; Dacre, Jane E; Peterfy, Charles G; Provvedini, Diego; Ravaud, Phillipe; Taccoen, Alain; Vignon, Eric
2002 Jun;29(6):1308-1320, Journal of rheumatology
— id: 142077, year: 2002, vol: 29, page: 1308, stat: Journal Article,

Field test of the reproducibility of the semiflexed metatarsophalangeal view in repeated radiographic examinations of subjects with osteoarthritis of the knee
Mazzuca, Steven A; Brandt, Kenneth D; Buckwalter, Kenneth A; Lane, Kathleen A; Katz, Barry P
2002 Jan;46(1):109-113, Arthritis & rheumatism
— id: 142074, year: 2002, vol: 46, page: 109, stat: Journal Article,

Knee pain reduces joint space width in conventional standing anteroposterior radiographs of osteoarthritic knees
Mazzuca, Steven A; Brandt, Kenneth D; Lane, Kathleen A; Katz, Barry P
2002 May;46(5):1223-1227, Arthritis & rheumatism
— id: 142079, year: 2002, vol: 46, page: 1223, stat: Journal Article,

Educational program for physicians to reduce use of non-steroidal anti-inflammatory drugs among community-dwelling elderly persons: a randomized controlled trial
Ray, W A; Stein, C M; Byrd, V; Shorr, R; Pichert, J W; Gideon, P; Arnold, K; Brandt, K D; Pincus, T; Griffin, M R
2001 May;39(5):425-435, Medical care
— id: 90253, year: 2001, vol: 39, page: 425, stat: Journal Article,

Practical management of osteoarthritis. Integration of pharmacologic and nonpharmacologic measures
Griffin, M R; Brandt, K D; Liang, M H; Pincus, T; Ray, W A
1995 Dec;4(12):1049-1055, Archives of family medicine
— id: 90301, year: 1995, vol: 4, page: 1049, stat: Journal Article,