Mary Helen Barcellos-Hoff, Ph.D.

Does microenvironment contribute to the etiology of estrogen receptor-negative breast cancer?
Barcellos-Hoff, Mary Helen
2013 Feb;19(3):541-548, Clinical cancer research
— id: 217992, year: 2013, vol: 19, page: 541, stat: Journal Article,

New biological insights on the link between radiation exposure and breast cancer risk
Barcellos-Hoff, Mary Helen
2013 Mar;18(1):3-13, Journal of mammary gland biology & neoplasia
— id: 248982, year: 2013, vol: 18, page: 3, stat: Journal Article,

Murine microenvironment metaprofiles associate with human cancer etiology and intrinsic subtypes
Nguyen, David H; Fredlund, Erik; Zhao, Wei; Perou, Charles M; Balmain, Allan; Mao, Jian-Hua; Barcellos-Hoff, Mary Helen
2013 Mar;19(6):1353-1362, Clinical cancer research
— id: 248132, year: 2013, vol: 19, page: 1353, stat: Journal Article,

Igf-I inhibition by pasireotide reverses the mammary phenotype of a novel mouse model of Brca1 deficiency
Ameri, P; Fernandez-Garcia, I; Martinez-Ruiz, H; De, Angelis C; Barcellos-Hoff, M H; Kleinberg, D L
2012 June 2012;33(3):-, Endocrine reviews
— id: 175839, year: 2012, vol: 33, page: , stat: Journal Article,

Radiation and endoplasmic reticulum stress-inducer promote calreticulin translocation, contributing to immunogenic cell death of cancer cells
Golden E.; Demaria S.; Barcellos-Hoff M.H.
2012 ;35(1):100-100, Journal of immunotherapy (Hagerstown)
— id: 149974, year: 2012, vol: 35, page: 100, stat: Journal Article,

The convergence of radiation and immunogenic cell death signaling pathways
Golden, Encouse B; Pellicciotta, Ilenia; Demaria, Sandra; Barcellos-Hoff, Mary H; Formenti, Silvia C
2012 ;2:88-88, Frontiers in oncology
— id: 177137, year: 2012, vol: 2, page: 88, stat: Journal Article,

Resistance of Glioblastoma-Initiating Cells to Radiation Mediated by the Tumor Microenvironment Can Be Abolished by Inhibiting Transforming Growth Factor-beta
Hardee, Matthew E; Marciscano, Ariel E; Medina-Ramirez, Christina M; Zagzag, David; Narayana, Ashwatha; Lonning, Scott M; Barcellos-Hoff, Mary Helen
2012 Aug;72(16):4119-4129, Cancer research
— id: 174385, year: 2012, vol: 72, page: 4119, stat: Journal Article,

TGFbeta is a master regulator of the pro-immunogenic effects of radiotherapy
Vanpouille-Box, C; Pilones, K A; Bouquet, S; Zavadil, J; Formenti, S; Barcellos-Hoff, M -H; Demaria, S
2012 November-December 2012;35(9):734-735, Journal of immunotherapy (Hagerstown)
— id: 185442, year: 2012, vol: 35, page: 734, stat: Journal Article,

Lack of radiation dose or quality dependence of epithelial-to-mesenchymal transition (EMT) mediated by transforming growth factor beta
Andarawewa, Kumari L; Costes, Sylvain V; Fernandez-Garcia, Ignacio; Chou, William S; Ravani, Shraddha A; Park, Howard; Barcellos-Hoff, Mary Helen
2011 Apr 1;79(5):1523-1531, International journal of radiation oncology biology physics
— id: 134227, year: 2011, vol: 79, page: 1523, stat: Journal Article,

Radiation-induced microenviornments and their role in carcinogenesis
Barcellos-Hoff MH; Nguyen DH
Tumor-Associated Fibroblasts and their Matrix Dordrecht : Springer, 2011,
— id: 5980, year: 2011, vol: , page: 267, stat: Chapter,

In honor of Mina J. Bissell
Barcellos-Hoff, Mary Helen
2011 Apr 1;3(4):253-254, Integrative Biology
— id: 130303, year: 2011, vol: 3, page: 253, stat: Journal Article,

TGFbeta Biology in Breast: 15 Years On
Barcellos-Hoff, Mary Helen
2011 Jun;16(2):65-66, Journal of mammary gland biology & neoplasia
— id: 132582, year: 2011, vol: 16, page: 65, stat: Journal Article,

What is the use of systems biology approaches in radiation biology?
Barcellos-Hoff, Mary Helen
2011 Mar;100(3):272-273, Health physics
— id: 150853, year: 2011, vol: 100, page: 272, stat: Journal Article,

Low-dose radiation knowledge worth the cost
Barcellos-Hoff, Mary Helen; Brenner, David J; Brooks, Antone L; Formenti, Silvia; Hlatky, Lyn; Locke, Paul A; Shore, Roy; Tenforde, Thomas; Travis, Elizabeth L; Williams, Jacqueline
2011 Apr 15;332(6027):305-306, Science
— id: 140490, year: 2011, vol: 332, page: 305, stat: Journal Article,

Increased radiosensitivity in vivo following inhibition of transforming growth factor beta in murine model of triple negative breast cancer
Bouquet S.F.; Pilones K.; Demaria S.; DeWyngaert K.J.; Lonning S.; Formenti S.; Barcellos-Hoff M.
2011 ;81:S714-S715, International journal of radiation oncology biology physics
— id: 150891, year: 2011, vol: 81, page: S714, stat: Journal Article,

TGFbeta1 Inhibition Increases the Radiosensitivity of Breast Cancer Cells In Vitro and Promotes Tumor Control by Radiation In Vivo
Bouquet, Fanny; Pal, Anupama; Pilones, Karsten A; Demaria, Sandra; Hann, Byron; Akhurst, Rosemary J; Babb, Jim S; Lonning, Scott M; Dewyngaert, J Keith; Formenti, Silvia C; Barcellos-Hoff, Mary Helen
2011 Nov 1;17(21):6754-6765, Clinical cancer research
— id: 140531, year: 2011, vol: 17, page: 6754, stat: Journal Article,

Persistence of gamma-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to gamma-rays or iron ions
Groesser, Torsten; Chang, Hang; Fontenay, Gerald; Chen, James; Costes, Sylvain V; Helen Barcellos-Hoff, Mary; Parvin, Bahram; Rydberg, Bjorn
2011 Jul;87(7):696-710, International journal of radiation biology
— id: 150856, year: 2011, vol: 87, page: 696, stat: Journal Article,

Multiscale iterative voting for differential analysis of stress response for 2D and 3D cell culture models
Han, J; Chang, H; Yang, Q; Fontenay, G; Groesser, T; Barcellos-Hoff, M Helen; Parvin, B
2011 Mar;241(3):315-326, Journal of microscopy
— id: 150854, year: 2011, vol: 241, page: 315, stat: Journal Article,

Development of a novel multiplexed-TGFbeta assay
Hardee M.E.; Marciscano A.E.; Rifkin D.B.; Barcellos-Hoff M.
2011 ;81(2 SUPPL 1):S755-S755, International journal of radiation oncology biology physics
— id: 150889, year: 2011, vol: 81, page: S755, stat: Journal Article,

TGFbeta inhibition radiosensitizes murine glioblastoma cells and decreases neurosphere-forming capacity
Hardee M.E.; Marciscano A.E.; Zagzag D.; Narayana A.; Barcellos-Hoff M.
2011 ;81(2 SUPPL 1):S714-S714, International journal of radiation oncology biology physics
— id: 150892, year: 2011, vol: 81, page: S714, stat: Journal Article,

The pivotal role of insulin-like growth factor I in normal mammary development
Kleinberg, David L; Barcellos-Hoff, Mary Helen
2011 Sep;40(3):193-204, Endocrinology & metabolism clinics of North America
— id: 137076, year: 2011, vol: 40, page: 193, stat: Journal Article,

Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer
Maxwell, Christopher A; Benitez, Javier; Gomez-Baldo, Laia; Osorio, Ana; Bonifaci, Nuria; Fernandez-Ramires, Ricardo; Costes, Sylvain V; Guino, Elisabet; Chen, Helen; Evans, Gareth J R; Mohan, Pooja; Catala, Isabel; Petit, Anna; Aguilar, Helena; Villanueva, Alberto; Aytes, Alvaro; Serra-Musach, Jordi; Rennert, Gad; Lejbkowicz, Flavio; Peterlongo, Paolo; Manoukian, Siranoush; Peissel, Bernard; Ripamonti, Carla B; Bonanni, Bernardo; Viel, Alessandra; Allavena, Anna; Bernard, Loris; Radice, Paolo; Friedman, Eitan; Kaufman, Bella; Laitman, Yael; Dubrovsky, Maya; Milgrom, Roni; Jakubowska, Anna; Cybulski, Cezary; Gorski, Bohdan; Jaworska, Katarzyna; Durda, Katarzyna; Sukiennicki, Grzegorz; Lubinski, Jan; Shugart, Yin Yao; Domchek, Susan M; Letrero, Richard; Weber, Barbara L; Hogervorst, Frans B L; Rookus, Matti A; Collee, J Margriet; Devilee, Peter; Ligtenberg, Marjolijn J; Luijt, Rob B van der; Aalfs, Cora M; Waisfisz, Quinten; Wijnen, Juul; Roozendaal, Cornelis E P van; Easton, Douglas F; Peock, Susan; Cook, Margaret; Oliver, Clare; Frost, Debra; Harrington, Patricia; Evans, D Gareth; Lalloo, Fiona; Eeles, Rosalind; Izatt, Louise; Chu, Carol; Eccles, Diana; Douglas, Fiona; Brewer, Carole; Nevanlinna, Heli; Heikkinen, Tuomas; Couch, Fergus J; Lindor, Noralane M; Wang, Xianshu; Godwin, Andrew K; Caligo, Maria A; Lombardi, Grazia; Loman, Niklas; Karlsson, Per; Ehrencrona, Hans; Wachenfeldt, Anna von; Barkardottir, Rosa Bjork; Hamann, Ute; Rashid, Muhammad U; Lasa, Adriana; Caldes, Trinidad; Andres, Raquel; Schmitt, Michael; Assmann, Volker; Stevens, Kristen; Offit, Kenneth; Curado, Joao; Tilgner, Hagen; Guigo, Roderic; Aiza, Gemma; Brunet, Joan; Castellsague, Joan; Martrat, Griselda; Urruticoechea, Ander; Blanco, Ignacio; Tihomirova, Laima; Goldgar, David E; Buys, Saundra; John, Esther M; Miron, Alexander; Southey, Melissa; Daly, Mary B; Schmutzler, Rita K; Wappenschmidt, Barbara; Meindl, Alfons; Arnold, Norbert; Deissler, Helmut; Varon-Mateeva, Raymonda; Sutter, Christian; Niederacher, Dieter; Imyamitov, Evgeny; Sinilnikova, Olga M; Stoppa-Lyonne, Dominique; Mazoyer, Sylvie; Verny-Pierre, Carole; Castera, Laurent; de Pauw, Antoine; Bignon, Yves-Jean; Uhrhammer, Nancy; Peyrat, Jean-Philippe; Vennin, Philippe; Fert Ferrer, Sandra; Collonge-Rame, Marie-Agnes; Mortemousque, Isabelle; Spurdle, Amanda B; Beesley, Jonathan; Chen, Xiaoqing; Healey, Sue; Barcellos-Hoff, Mary Helen; Vidal, Marc; Gruber, Stephen B; Lazaro, Conxi; Capella, Gabriel; McGuffog, Lesley; Nathanson, Katherine L; Antoniou, Antonis C; Chenevix-Trench, Georgia; Fleisch, Markus C; Moreno, Victor; Pujana, Miguel Angel
2011 Nov;9(11):e1001199-e1001199, PLoS biology
— id: 150852, year: 2011, vol: 9, page: e1001199, stat: Journal Article,

TGF-beta biology in mammary development and breast cancer
Moses, Harold; Barcellos-Hoff, Mary Helen
2011 Jan;3(1):a003277-a003277, Cold Spring Harbor perspectives in biology
— id: 138152, year: 2011, vol: 3, page: a003277, stat: Journal Article,

The biological impact of radiation exposure on breast cancer development
Nguyen, David H; Bochaca, Irineu Illa; Barcellos-Hoff, Mary Helen
Environment and breast cancer New York : Springer, c2011,
— id: 5981, year: 2011, vol: , page: 185, stat: Chapter,

Consequences of Epithelial or Stromal TGFbeta1 Depletion in the Mammary Gland
Nguyen, David H; Martinez-Ruiz, Haydeliz; Barcellos-Hoff, Mary Helen
2011 Jun;16(2):147-155, Journal of mammary gland biology & neoplasia
— id: 134199, year: 2011, vol: 16, page: 147, stat: Journal Article,

Radiation Acts on the Microenvironment to Affect Breast Carcinogenesis by Distinct Mechanisms that Decrease Cancer Latency and Affect Tumor Type
Nguyen, David H; Oketch-Rabah, Hellen A; Illa-Bochaca, Irineu; Geyer, Felipe C; Reis-Filho, Jorge S; Mao, Jian-Hua; Ravani, Shraddha A; Zavadil, Jiri; Borowsky, Alexander D; Jerry, D Joseph; Dunphy, Karen A; Seo, Jae Hong; Haslam, Sandra; Medina, Daniel; Barcellos-Hoff, Mary Helen
2011 May 17;19(5):640-651, Cancer cell
— id: 132592, year: 2011, vol: 19, page: 640, stat: Journal Article,

Multiplicity of Favorable Effects after Transforming Growth Factor-beta Inhibition in 4T1 Murine Mammary Tumors: Clinical Implications
Barcellos-Hoff, M. H.; Bouquet, S. F.; Pilones, K. A.; Demaria, S.; Formenti, S. C.
2010 OCT 13 ;78(3):S648-S648, International journal of radiation oncology biology physics
— id: 114022, year: 2010, vol: 78, page: S648, stat: Journal Article,

Stromal mediation of radiation carcinogenesis
Barcellos-Hoff, Mary Helen
2010 Dec;15(4):381-387, Journal of mammary gland biology & neoplasia
— id: 116242, year: 2010, vol: 15, page: 381, stat: Journal Article,

Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization
Costes, S V; Chiolo, I; Pluth, J M; Barcellos-Hoff, M H; Jakob, B
2010 Apr-Jun;704(1-3):78-87, Mutation research
— id: 116247, year: 2010, vol: 704, page: 78, stat: Journal Article,

Microenvironment and cell fate determination in MCF10A is mediated by ionizing radiation, TGFbeta and the extracellular matrix
Fernandez-Garcia, I; Paupert, J; Barcellos-Hoff, M
2010 15 Dec 2010;21(24):-, Molecular biology of the cell
— id: 157725, year: 2010, vol: 21, page: , stat: Journal Article,

In situ analysis of cell populations: long-term label-retaining cells
Fernandez-Gonzalez, Rodrigo; Illa-Bochaca, Irineu; Shelton, Dawne N; Welm, Bryan E; Barcellos-Hoff, Mary Helen; Ortiz-de-Solorzano, Carlos
2010 ;621:1-28, Methods in molecular biology
— id: 116244, year: 2010, vol: 621, page: 1, stat: Journal Article,

Multidimensional profiling of cell surface proteins and nuclear markers
Han, Ju; Chang, Hang; Andarawewa, Kumari; Yaswen, Paul; Barcellos-Hoff, Mary Helen; Parvin, Bahram
2010 Jan-Mar;7(1):80-90, IEEE/ACM transactions on computational biology & bioinformatics
— id: 116245, year: 2010, vol: 7, page: 80, stat: Journal Article,

Limiting-dilution transplantation assays in mammary stem cell studies
Illa-Bochaca, Irineu; Fernandez-Gonzalez, Rodrigo; Shelton, Dawne N; Welm, Bryan E; Ortiz-de-Solorzano, Carlos; Barcellos-Hoff, Mary Helen
2010 ;621:29-47, Methods in molecular biology
— id: 109217, year: 2010, vol: 621, page: 29, stat: Journal Article,

Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies
Mukhopadhyay, Rituparna; Costes, Sylvain V; Bazarov, Alexey V; Hines, William C; Barcellos-Hoff, Mary Helen; Yaswen, Paul
2010 ;12(1):R11-R11, Breast cancer research
— id: 116246, year: 2010, vol: 12, page: R11, stat: Journal Article,

Use of stem cell markers in dissociated mammary populations
Shelton, Dawne N; Fernandez-Gonzalez, Rodrigo; Illa-Bochaca, Irineu; Ortiz-de-Solorzano, Carlos; Barcellos-Hoff, Mary Helen; Welm, Bryan E
2010 ;621:49-55, Methods in molecular biology
— id: 116243, year: 2010, vol: 621, page: 49, stat: Journal Article,

Transforming growth factor-beta in breast cancer: too much, too late
Barcellos-Hoff, Mary Helen; Akhurst, Rosemary J
2009 ;11(1):202-202, Breast cancer research
— id: 99208, year: 2009, vol: 11, page: 202, stat: Journal Article,

Integrating biology and technology
Barcellos-Hoff, Mary Helen; Beebe, David
2009 Jan;1(1):14-14, Integrative Biology
— id: 116250, year: 2009, vol: 1, page: 14, stat: Journal Article,

Editorial: Resistance to radio- and chemotherapy and the tumour microenvironment
Barcellos-Hoff, Mary Helen; Cordes, Nils
2009 Nov;85(11):920-922, International journal of radiation biology
— id: 105535, year: 2009, vol: 85, page: 920, stat: Journal Article,

Therapeutic targets in malignant glioblastoma microenvironment
Barcellos-Hoff, Mary Helen; Newcomb, Elizabeth W; Zagzag, David; Narayana, Ashwatha
2009 Jul;19(3):163-170, Seminars in radiation oncology
— id: 99219, year: 2009, vol: 19, page: 163, stat: Journal Article,

Radiation carcinogenesis in context: how do irradiated tissues become tumors?
Barcellos-Hoff, MH; Nguyen, DH
2009 ;97(5):446-457, Health physics
— id: 104662, year: 2009, vol: 97, page: 446, stat: Journal Article,

The development of integrative biology: bridging the gap--a view from the Scientific Editors. [An interview with David Beebe and Mary Helen Barcellos-Hoff by Kathleen Too]
Beebe, David; Barcellos-Hoff, Mary Helen
2009 Feb;1(2):145-147, Integrative Biology
— id: 116248, year: 2009, vol: 1, page: 145, stat: Journal Article,

Mapping mammary gland architecture using multi-scale in situ analysis
Fernandez-Gonzalez, Rodrigo; Illa-Bochaca, Irineu; Welm, Bryan E; Fleisch, Markus C; Werb, Zena; Ortiz-de-Solorzano, Carlos; Barcellos-Hoff, Mary Helen
2009 Jan;1(1):80-89, Integrative Biology
— id: 116249, year: 2009, vol: 1, page: 80, stat: Journal Article,

Host biology affects the frequency of ER plus breast cancer
Nguyen, David; Oketch-Rabah, Hellen; Barcellos-Hoff, Mary Helen
2009 ;50(Suppl. S):577-577, Proceedings (American Association for Cancer Research)
— id: 104661, year: 2009, vol: 50, page: 577, stat: Journal Article,

Estrogen and progesterone receptors have distinct roles in the establishment of the hyperplastic phenotype in PR-A transgenic mice
Simian, Marina; Bissell, Mina J; Barcellos-Hoff, Mary Helen; Shyamala, Gopalan
2009 Sep 29;11(5):R72-R72, Breast cancer research
— id: 105536, year: 2009, vol: 11, page: R72, stat: Journal Article,

Persistent phenotypic responses of human mammary epithelial cells induced by ionizing radiation
Andarawewa K.L.; Chou W.S.; Costes S.V.; Barcellos-Hoff M.H.
2008 ;53(SUPPL.):61-63, Acta Medica Nagasakiensia
— id: 99261, year: 2008, vol: 53, page: 61, stat: Journal Article,

TGF beta: Roles in DNA damage responses
Andarawewa, Kumari L.; Kirshner, Julia; Mott, Joni D.; Barcellos-Hoff, Mary Helen
Transforming growth factor-[beta] in cancer therapy Totowa, N.J. : Humana Press, 2008,
— id: 5234, year: 2008, vol: , page: 321, stat: Chapter,

Bioavailability of TGF-beta in breast cancer
Barcellos-Hoff, Mary H; Bochaca, Irineu I
Ft. Belvoir VA : Defense Technical Information Center, 2008,
— id: 2092, year: 2008, vol: , page: , stat: ,

Cancer as an emergent phenomenon in systems radiation biology
Barcellos-Hoff, Mary Helen
2008 Feb;47(1):33-38, Radiation & environmental biophysics
— id: 83249, year: 2008, vol: 47, page: 33, stat: Journal Article,

The genomic differences in radiated breast - Epithelial cells is centrosome given - Implication for the increased risk during continually radiated breast cancer
Fleisch, MC; Maxwell, CA; Costes, SV; Barcellos-Hoff, MH
2008 ;68(20):S104-S104, Geburtshilfe & Frauenheilkunde
— id: 104664, year: 2008, vol: 68, page: S104, stat: Journal Article,

Integrated profiling of cell surface protein and nuclear marker for discriminant analysis
Ju Han; Hang Chang; Andarawewa, K.; Yaswen, P.; Barcellos-Hoff, M.H.; Parvin, B.J.
2008 5th IEEE International Symposium on Biomedical Imaging from nano to macro : proceedings [Piscataway, N.J.] : IEEE, 2008,
— id: 5225, year: 2008, vol: , page: 1343, stat: Chapter,

Targeted and nontargeted effects of ionizing radiation that impact genomic instability
Maxwell, Christopher A; Fleisch, Markus C; Costes, Sylvain V; Erickson, Anna C; Boissiere, Arnaud; Gupta, Rishi; Ravani, Shraddha A; Parvin, Bahram; Barcellos-Hoff, Mary Helen
2008 Oct 15;68(20):8304-8311, Cancer research
— id: 93861, year: 2008, vol: 68, page: 8304, stat: Journal Article,

Inhibition of transforming growth factor betal (TGF beta 1) signaling increases radiosensitivity in breast cancer cell lines
Pal, Anupama; Gascard, Philippe D.; Ravani, Shraddha A.; Barcellos-Hoff, Mary Helen
2008 ;49(1):98-98, Proceedings (American Association for Cancer Research)
— id: 104663, year: 2008, vol: 49, page: 98, stat: Journal Article,

Karyotypic instability and centrosome aberrations in the progeny of finite life-span human mammary epithelial cells exposed to sparsely or densely ionizing radiation
Sudo, Hiroko; Garbe, James; Stampfer, Martha R; Barcellos-Hoff, Mary Helen; Kronenberg, Amy
2008 Jul;170(1):23-32, Radiation research
— id: 83266, year: 2008, vol: 170, page: 23, stat: Journal Article,

Genomic approaches to breast cancer subset identification and treatment
Albertson, D; Chin, K; Devries, S; Feiler, H; Pinkel, D; Spellman, P; Waldman, F; Wang, N; Hennessy, B; Mills, G; Barcellos, HMH; Bissell, M; Guan, Y; Hu, Z; Kuo, WL; McCormick, F; Neve, R; Stampfer, M; Wooster, R; Yaswen, P; Das, D; Fridlyand, J; Correll, E; Jin, J; Nordmeyer, B; Sudar, D; Chew, K; Dairkee, S; Ljung, BM; Hwang, S; Esserman, L; Arbushites, M; Benz, C; Koehler, M; Marks, JD; Zhou, Y; Park, J; Weber, B; Gray, J
2007 ;106(11-12):S10-S10, Breast cancer research & treatment
— id: 104667, year: 2007, vol: 106, page: S10, stat: Journal Article,

Ionizing radiation induces TGF beta mediated epithelial to mesenchy mal transition through persistent activation of Erk;
Andarawewa, Kumari L.; Erickson, Anna C.; Chou, William S.; Mott, Joni D.; Gascard, Pilippe; Barcellos-Hoff, Mary Helen
2007 ;48(20):1013-1013, Proceedings (American Association for Cancer Research)
— id: 104665, year: 2007, vol: 48, page: 1013, stat: Journal Article,

Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition
Andarawewa, Kumari L; Erickson, Anna C; Chou, William S; Costes, Sylvain V; Gascard, Philippe; Mott, Joni D; Bissell, Mina J; Barcellos-Hoff, Mary Helen
2007 Sep 15;67(18):8662-8670, Cancer research
— id: 83248, year: 2007, vol: 67, page: 8662, stat: Journal Article,

New rationales for using TGFbeta inhibitors in radiotherapy
Andarawewa, Kumari L; Paupert, Jenny; Pal, Anupama; Barcellos-Hoff, Mary Helen
2007 Nov-Dec;83(11-12):803-811, International journal of radiation biology
— id: 83251, year: 2007, vol: 83, page: 803, stat: Journal Article,

Radiation therapy and the microenvironment
Barcellos-Hoff, Mary Helen; Cordes, Nils
2007 Nov-Dec;83(11-12):723-725, International journal of radiation biology
— id: 83250, year: 2007, vol: 83, page: 723, stat: Journal Article,

Perceptual grouping of membrane signals in cell-based assays
Chang, H.; Andarawewa, K.L.; Han, J.; Barcellos-Hoff, M.H.; Parvin, B.
Piscataway, N.J. : IEEE, 2007,
— id: 5226, year: 2007, vol: , page: 532, stat: Chapter,

Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains
Costes, Sylvain V; Ponomarev, Artem; Chen, James L; Nguyen, David; Cucinotta, Francis A; Barcellos-Hoff, Mary Helen
2007 Aug;3(8):e155-e155, PLoS Computational Biology
— id: 83246, year: 2007, vol: 3, page: e155, stat: Journal Article,

Segmentation of mammosphere structures from volumetric data
Ju Han; Hang Chang; Qing Yang; Barcellos-Hoff , M.H.; Parvin, B.
2007 4th IEEE International Symposium on Biomedical Imaging from nano to macro : proceedings Piscataway, N.J. : IEEE, 2007,
— id: 5227, year: 2007, vol: , page: 524, stat: Chapter,

The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression
Kenny, Paraic A; Lee, Genee Y; Myers, Connie A; Neve, Richard M; Semeiks, Jeremy R; Spellman, Paul T; Lorenz, Katrin; Lee, Eva H; Barcellos-Hoff, Mary Helen; Petersen, Ole W; Gray, Joe W; Bissell, Mina J
2007 Jun;1(1):84-96, Molecular oncology
— id: 83265, year: 2007, vol: 1, page: 84, stat: Journal Article,

Response of a human breast cell line to transforming growth factor-beta (TGF-beta) is context specific and involves components of TGF-beta and the epidermal growth factor receptor signaling pathways
Mott, Joni D.; Barcellos-Hoff, Mary Helen
2007 ;48(18):896-896, Proceedings (American Association for Cancer Research)
— id: 104666, year: 2007, vol: 48, page: 896, stat: Journal Article,

Iterative voting for inference of structural saliency and characterization of subcellular events
Parvin, Bahram; Yang, Qing; Han, Ju; Chang, Hang; Rydberg, Bjorn; Barcellos-Hoff, Mary Helen
2007 Mar;16(3):615-623, IEEE transactions on image processing
— id: 83237, year: 2007, vol: 16, page: 615, stat: Journal Article,

Geometric approach to segmentation and protein localization in cell culture assays
Raman, S; Maxwell, C A; Barcellos-Hoff, M H; Parvin, B
2007 Jan;225(Pt 1):22-30, Journal of microscopy
— id: 83232, year: 2007, vol: 225, page: 22, stat: Journal Article,

Persistent activation of Erk in the progeny of irradiated human mammary epithelial cells during TGF beta-induced epithelial to mesenchymal transition
Andarawewa, Kumari L.; Erickson, Anna C.; Chou, William S.; Barcellos-Hoff, Mary Helen
2006 ;47(1):651-651, Proceedings (American Association for Cancer Research)
— id: 104668, year: 2006, vol: 47, page: 651, stat: Journal Article,

A systems biology approach to multicellular and multi-generational radiation responses
Barcellos-Hoff, Mary Helen; Costes, Sylvain V
2006 May 11;597(1-2):32-38, Mutation research
— id: 83213, year: 2006, vol: 597, page: 32, stat: Journal Article,

Multicellular and multigenerational responses to TGF beta
Barcellos-Hoff, MH
2006 ;27(1-2):32-32, Tumour biology
— id: 104669, year: 2006, vol: 27, page: 32, stat: Journal Article,

Imaging features that discriminate between foci induced by high- and low-LET radiation in human fibroblasts
Costes, Sylvain V; Boissiere, Arnaud; Ravani, Shraddha; Romano, Raquel; Parvin, Bahram; Barcellos-Hoff, Mary Helen
2006 May;165(5):505-515, Radiation research
— id: 83217, year: 2006, vol: 165, page: 505, stat: Journal Article,

Quantitative in vivo microscopy: the return from the 'omics'
Fernandez-Gonzalez, Rodrigo; Munoz-Barrutia, Arrate; Barcellos-Hoff, Mary Helen; Ortiz-de-Solorzano, Carlos
2006 Oct;17(5):501-510, Current opinion in biotechnology
— id: 83223, year: 2006, vol: 17, page: 501, stat: Journal Article,

The pleiotropic roles of transforming growth factor beta in homeostasis and carcinogenesis of endocrine organs
Fleisch, Markus C; Maxwell, Christopher A; Barcellos-Hoff, Mary-Helen
2006 Jun;13(2):379-400, Endocrine-related cancer
— id: 83219, year: 2006, vol: 13, page: 379, stat: Journal Article,

Intensity-based signal separation algorithm for accurate quantification of clustered centrosomes in tissue sections
Fleisch, Markus C; Maxwell, Christopher A; Kuper, Claudia K; Brown, Erika T; Barcellos-Hoff, Mary Helen; Costes, Sylvain V
2006 Dec;69(12):964-972, Microscopy research & technique
— id: 83224, year: 2006, vol: 69, page: 964, stat: Journal Article,

Loss of TGF-beta promotes accumulation of centrosome amplification and karyotypic abnormalities in p53 competent mammary cells and tissues
Fleisch, MC; Maxwell, CA; Kuper, CK; Costes, SV; Barcellos-Hoff, MH
2006 ;100(12):S290-S291, Breast cancer research & treatment
— id: 104670, year: 2006, vol: 100, page: S290, stat: Journal Article,

Isoform-specific activation of latent transforming growth factor beta (LTGF-beta) by reactive oxygen species
Jobling, Michael F; Mott, Joni D; Finnegan, Monica T; Jurukovski, Vladimir; Erickson, Anna C; Walian, Peter J; Taylor, Scott E; Ledbetter, Steven; Lawrence, Catherine M; Rifkin, Daniel B; Barcellos-Hoff, Mary Helen
2006 Dec;166(6):839-848, Radiation research
— id: 83229, year: 2006, vol: 166, page: 839, stat: Journal Article,

3D segmentation of mammospheres for localization studies
Ju Han; Hang Chang; Qing Yang; Barcellos-Hoff, M.H.; Parvin, B.
Advances in visual computing : second international symposium, ISVC 2006, Lake Tahoe, NV, USA, November 6-8, 2006 : proceedings New York : Springer, 2006,
— id: 5228, year: 2006, vol: , page: 518, stat: Chapter,

Inhibition of transforming growth factor-beta1 signaling attenuates ataxia telangiectasia mutated activity in response to genotoxic stress
Kirshner, Julia; Jobling, Michael F; Pajares, Maria Jose; Ravani, Shraddha A; Glick, Adam B; Lavin, Martin J; Koslov, Sergei; Shiloh, Yosef; Barcellos-Hoff, Mary Helen
2006 Nov 15;66(22):10861-10869, Cancer research
— id: 83228, year: 2006, vol: 66, page: 10861, stat: Journal Article,

Activated type I TGFbeta receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression
Muraoka-Cook, R S; Shin, I; Yi, J Y; Easterly, E; Barcellos-Hoff, M H; Yingling, J M; Zent, R; Arteaga, C L
2006 Jun 8;25(24):3408-3423, Oncogene
— id: 83206, year: 2006, vol: 25, page: 3408, stat: Journal Article,

How tissues respond to damage at the cellular level: orchestration by transforming growth factor-{beta} (TGF-{beta})
Barcellos-Hoff, M H
2005 ;27:123-127, BJR supplement / BIR
— id: 83200, year: 2005, vol: 27, page: 123, stat: Journal Article,

Integrative radiation carcinogenesis: interactions between cell and tissue responses to DNA damage
Barcellos-Hoff, Mary Helen
2005 Apr;15(2):138-148, Seminars in cancer biology
— id: 83196, year: 2005, vol: 15, page: 138, stat: Journal Article,

New highlights on stroma-epithelial interactions in breast cancer
Barcellos-Hoff, Mary Helen; Medina, Daniel
2005 ;7(1):33-36, Breast cancer research
— id: 83195, year: 2005, vol: 7, page: 33, stat: Journal Article,

Radiation and the microenvironment - tumorigenesis and therapy
Barcellos-Hoff, Mary Helen; Park, Catherine; Wright, Eric G
2005 Nov;5(11):867-875, Nature reviews. Cancer
— id: 83210, year: 2005, vol: 5, page: 867, stat: Journal Article,

Proliferation of estrogen receptor-alpha-positive mammary epithelial cells is restrained by transforming growth factor-beta1 in adult mice
Ewan, Kenneth B R; Oketch-Rabah, Hellen A; Ravani, Shraddha A; Shyamala, G; Moses, Harold L; Barcellos-Hoff, Mary Helen
2005 Aug;167(2):409-417, American journal of pathology
— id: 83202, year: 2005, vol: 167, page: 409, stat: Journal Article,

A tool for the quantitative spatial analysis of complex cellular systems
Fernandez-Gonzalez, Rodrigo; Barcellos-Hoff, Mary Helen; Ortiz-de-Solorzano, Carlos
2005 Sep;14(9):1300-1313, IEEE transactions on image processing
— id: 83207, year: 2005, vol: 14, page: 1300, stat: Journal Article,

A tool for the quantitative spatial analysis of heterogeneous cell populations
Fernandez-Gonzalez, Rodrigo; Ortiz de Solorzano, Carlos; Barcellos-Hoff, Mary Helen
2005 ;46(2):384-385, Proceedings (American Association for Cancer Research)
— id: 104671, year: 2005, vol: 46, page: 384, stat: Journal Article,

Cell cycle defects contribute to a block in hormone-induced mammary gland proliferation in CCAAT/enhancer-binding protein (C/EBPbeta)-null mice
Grimm, Sandra L; Contreras, Alejandro; Barcellos-Hoff, Mary-Helen; Rosen, Jeffrey M
2005 Oct 28;280(43):36301-36309, Journal of biological chemistry
— id: 83204, year: 2005, vol: 280, page: 36301, stat: Journal Article,

Three-dimensional histology of the mammary gland: An application to the study of hormone receptor expression during normal mammary gland development
Laribi, Ouahiba; Hartland, Abbey; Fernandez-Gonzalez, Rodrigo; Arganda-Carreras, Ignacio; Idica, Adam; Barcellos-Hoff, Mary Helen; Ortiz de Solorzano, Carlos
2005 ;46(43):1241-1241, Proceedings (American Association for Cancer Research)
— id: 104672, year: 2005, vol: 46, page: 1241, stat: Journal Article,

Targeting cell-extracellular matrix (ECM) interactions to enhance radiation efficacy for breast cancer treatment
Park, Catherine C.; Zhang, Hui J.; Yao, Evelyn; Barcellos-Hoff, Mary Helen; Bissell, Mina J.
2005 ;46(43):390-391, Proceedings (American Association for Cancer Research)
— id: 104673, year: 2005, vol: 46, page: 390, stat: Journal Article,

Geometric approach to segmentation and protein localization in cell cultured assays
Raman, S; Parvin, B; Maxwell, C; Barcellos-Hoff, MH
2005 ;3804(43):427-436, Medical image computing & computer-assisted intervention : MICCAI
— id: 104674, year: 2005, vol: 3804, page: 427, stat: Journal Article,

Quantitative image analysis in mammary gland biology
Fernandez-Gonzalez, Rodrigo; Barcellos-Hoff, Mary Helen; Ortiz-de-Solorzano, Carlos
2004 Oct;9(4):343-359, Journal of mammary gland biology & neoplasia
— id: 83198, year: 2004, vol: 9, page: 343, stat: Journal Article,

Conditional overexpression of active transforming growth factor beta1 in vivo accelerates metastases of transgenic mammary tumors
Muraoka-Cook, Rebecca S; Kurokawa, Hirokazu; Koh, Yasuhiro; Forbes, James T; Roebuck, L Renee; Barcellos-Hoff, Mary Helen; Moody, Susan E; Chodosh, Lewis A; Arteaga, Carlos L
2004 Dec 15;64(24):9002-9011, Cancer research
— id: 83193, year: 2004, vol: 64, page: 9002, stat: Journal Article,

Localization of saliency through iterative voting
Qing Yang; Parvin, B.; Barcellos-Hoff, M.H.
Proceedings of the 17th International Conference on Pattern Recognition : ICPR 2004 Los Alamitos, Calif. : IEEE Computer Society Press, 2004,
— id: 5229, year: 2004, vol: , page: 63, stat: Chapter,

Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003
Stone, Helen B; Moulder, John E; Coleman, C Norman; Ang, K Kian; Anscher, Mitchell S; Barcellos-Hoff, Mary Helen; Dynan, William S; Fike, John R; Grdina, David J; Greenberger, Joel S; Hauer-Jensen, Martin; Hill, Richard P; Kolesnick, Richard N; Macvittie, Thomas J; Marks, Cheryl; McBride, William H; Metting, Noelle; Pellmar, Terry; Purucker, Mary; Robbins, Mike E; Schiestl, Robert H; Seed, Thomas M; Tomaszewski, Joseph E; Travis, Elizabeth L; Wallner, Paul E; Wolpert, Mary; Zaharevitz, Daniel
2004 Dec;162(6):711-728, Radiation research
— id: 83189, year: 2004, vol: 162, page: 711, stat: Journal Article,

The role of TGF-beta in radiation responses
Barcellos-Hoff, M. H.
2003 ;1(5):S227-S227, EJC Supplements
— id: 104677, year: 2003, vol: 1, page: S227, stat: Journal Article,

How radiation-induced phenotypes contribute to neoplastic progression
Barcellos-Hoff, MH
2003 ;85(1):84-84, Health physics
— id: 104675, year: 2003, vol: 85, page: 84, stat: Journal Article,

Radiation-induced versus endogenous DNA damage: commentary on Pollycove and Feinendegen
Barcellos-Hoff, MH
2003 ;22(6):307-307, Human & Experimental Toxicology
— id: 104676, year: 2003, vol: 22, page: 307, stat: Journal Article,

Education and training for radiation scientists: radiation research program and American Society of Therapeutic Radiology and Oncology Workshop, Bethesda, Maryland, May 12-14, 2003
Coleman, C Norman; Stone, Helen B; Alexander, George A; Barcellos-Hoff, Mary Helen; Bedford, Joel S; Bristow, Robert G; Dynlacht, Joseph R; Fuks, Zvi; Gorelic, Lester S; Hill, Richard P; Joiner, Michael C; Liu, Fei-Fei; McBride, William H; McKenna, W Gillies; Powell, Simon N; Robbins, Michael E C; Rockwell, Sara; Schiff, Peter B; Shaw, Edward G; Siemann, Dietmar W; Travis, Elizabeth L; Wallner, Paul E; Wong, Rosemary S L; Zeman, Elaine M
2003 Dec;160(6):729-737, Radiation research
— id: 83174, year: 2003, vol: 160, page: 729, stat: Journal Article,

The not-so innocent bystander: the microenvironment as a therapeutic target in cancer
Erickson, Anna C; Barcellos-Hoff, Mary Helen
2003 Feb;7(1):71-88, Expert opinion on therapeutic targets
— id: 83157, year: 2003, vol: 7, page: 71, stat: Journal Article,

Isoform specificity of redox-mediated TGF-beta activation
Jobling, M; Erickson, A; Taylor, S; Finnigan, M; Ledbetter, S; Lawrence, C; Barcellos-Hoff, MH
2003 ;35(1):25-25, Free radical biology & medicine
— id: 104678, year: 2003, vol: 35, page: 25, stat: Journal Article,

"Radiation-induced p53 Ser-18 phosphorylation is TGF-beta1 dependent in primary epithelial, but not fibroblast, cells"
Pajares, Maria J.; Glick, Adam; Jobling, Michael F.; Barcellos-Hoff, Mary Helen
2003 ;44(1):465-465, Proceedings (American Association for Cancer Research)
— id: 104679, year: 2003, vol: 44, page: 465, stat: Journal Article,

Ionizing radiation induces heritable disruption of epithelial cell interactions
Park, Catherine C; Henshall-Powell, Rhonda L; Erickson, Anna C; Talhouk, Rabih; Parvin, Bahram; Bissell, Mina J; Barcellos-Hoff, Mary Helen
2003 Sep 16;100(19):10728-10733, Proceedings of the National Academy of Sciences of the United States of America
— id: 83169, year: 2003, vol: 100, page: 10728, stat: Journal Article,

BioSig: an imaging bioinformatics system for phenotypic analysis
Parvin, B; Yang, Qing; Fontenay, G; Barcellos-Hoff, M H
2003 ;33(5):814-824, IEEE transactions on systems, man, & cybernetics. Part B, Cybernetics
— id: 83255, year: 2003, vol: 33, page: 814, stat: Journal Article,

Transforming growth factor beta1 mediates radiation-induced apoptosis and p53 response in situ
Barcellos-Hoff, Mary H.; Henshall-Powell, Rhonda; Ewan, Kenneth B.; Ravani, Shraddha A.; Arteaga, Carlos; Akhurst, Rosemary; Warters, Ray; Parvin, Bahram
2002 ;43(4):147-147, Proceedings (American Association for Cancer Research)
— id: 104680, year: 2002, vol: 43, page: 147, stat: Journal Article,

The contribution of radiation-induced microenvironments to neoplastic progression
Barcellos-Hoff, MH
2002 ;158(6):792-793, Radiation research
— id: 104681, year: 2002, vol: 158, page: 792, stat: Journal Article,

Radiation quality and tissue-specific microenvironments following exposure to 1 GeV/amu Fe
Costes, S; Barcellos-Hoff, M H
2002 ;30(4):865-870, Advances in space research : the official journal of the Committee on Space Research (COSPAR)
— id: 83154, year: 2002, vol: 30, page: 865, stat: Journal Article,

Radiation alters cytoskeletal association of E-cadherin in TGF-beta 1 treated human mammary epithelial cells
Erickson, AC; Chou, WS; Henshall-Powell, R; Bissell, MJ; Barcellos-Hoff, MH
2002 ;13(2):409-409, Molecular biology of the cell
— id: 104682, year: 2002, vol: 13, page: 409, stat: Journal Article,

Transforming growth factor-beta1 mediates cellular response to DNA damage in situ
Ewan, Kenneth B; Henshall-Powell, Rhonda L; Ravani, Shraddha A; Pajares, Maria Jose; Arteaga, Carlos; Warters, Ray; Akhurst, Rosemary J; Barcellos-Hoff, Mary Helen
2002 Oct 15;62(20):5627-5631, Cancer research
— id: 83149, year: 2002, vol: 62, page: 5627, stat: Journal Article,

Latent transforming growth factor-beta activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation
Ewan, Kenneth B; Shyamala, Gopalan; Ravani, Shraddha A; Tang, Yang; Akhurst, Rosemary; Wakefield, Lalage; Barcellos-Hoff, Mary Helen
2002 Jun;160(6):2081-2093, American journal of pathology
— id: 83144, year: 2002, vol: 160, page: 2081, stat: Journal Article,

System for combined three-dimensional morphological and molecular analysis of thick tissue specimens
Fernandez-Gonzalez, Rodrigo; Jones, Arthur; Garcia-Rodriguez, Enrique; Chen, Ping Yuan; Idica, Adam; Lockett, Stephen J; Barcellos-Hoff, Mary Helen; Ortiz-De-Solorzano, Carlos
2002 Dec 15;59(6):522-530, Microscopy research & technique
— id: 83151, year: 2002, vol: 59, page: 522, stat: Journal Article,

Redox-mediated TGFbeta activation: Site specific oxidation of TGFbeta1
Jobling, Michael; Ledbetter, Steven; Finnigan, Monica; Lawrence, Cathy; Barcellos-Hoff, Mary Helen
2002 ;43(6):385-385, Proceedings (American Association for Cancer Research)
— id: 104683, year: 2002, vol: 43, page: 385, stat: Journal Article,

Applications of quantitative digital image analysis to breast cancer research
Ortiz De Solorzano, C; Costes, S; Callahan, D E; Parvin, B; Barcellos-Hoff, M H
2002 Oct 15;59(2):119-127, Microscopy research & technique
— id: 83148, year: 2002, vol: 59, page: 119, stat: Journal Article,

BioSig: An imaging bioinformatic system for studying phenomics
Parvin, B; Yang, Q; Fontenay, G; Barcellos-Hoff, MH
2002 ;35(7):65-+, Computer (IEEE Computer Society)
— id: 104684, year: 2002, vol: 35, page: 65, stat: Journal Article,

Microscopy environment for quantitative spatial and temporal analysis of multicellular interactions
Sudar, D; Parvin, B; Callahan, DE; Schwarz, RI; Knowles, DW; de Solorzano, CO; Barcellos-Hoff, MH
Three-dimensional and multidimensional microscopy : image acquisition and processing IX Bellingham, WA : SPIE, 2002,
— id: 5230, year: 2002, vol: , page: 47, stat: Chapter,

Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts
Wang, Fei; Hansen, Rhonda K; Radisky, Derek; Yoneda, Toshiyuki; Barcellos-Hoff, Mary Helen; Petersen, Ole W; Turley, Eva A; Bissell, Mina J
2002 Oct 2;94(19):1494-1503, Journal of the National Cancer Institute
— id: 83147, year: 2002, vol: 94, page: 1494, stat: Journal Article,

Epigenetics and breast cancer
Asch, B B; Barcellos-Hoff, M H
2001 Apr;6(2):151-152, Journal of mammary gland biology & neoplasia
— id: 83134, year: 2001, vol: 6, page: 151, stat: Journal Article,

Epigenetic mechanisms controlling gene expression in breast cancer
Asch, Bonnie B; Barcellos-Hoff, Mary Helen
New York NY : Kluwer Academic/Plenum, 2001,
— id: 2094, year: 2001, vol: , page: , stat: ,

It takes a tissue to make a tumor: epigenetics, cancer and the microenvironment
Barcellos-Hoff, M H
2001 Apr;6(2):213-221, Journal of mammary gland biology & neoplasia
— id: 83135, year: 2001, vol: 6, page: 213, stat: Journal Article,

Three down and counting: the transformation of human mammary cells from normal to malignant in three steps
Barcellos-Hoff, M H
2001 Apr;7(4):142-143, Trends in molecular medicine
— id: 83131, year: 2001, vol: 7, page: 142, stat: Journal Article,

Extracellular signaling through the microenvironment: a hypothesis relating carcinogenesis, bystander effects, and genomic instability
Barcellos-Hoff, M H; Brooks, A L
2001 Nov;156(5 Pt 2):618-627, Radiation research
— id: 83136, year: 2001, vol: 156, page: 618, stat: Journal Article,

Immunodetection of 3-nitrotyrosine in the liver of zymosan-treated rats with a new monoclonal antibody: comparison to analysis by HPLC
Girault, I; Karu, A E; Schaper, M; Barcellos-Hoff, M H; Hagen, T; Vogel, D S; Ames, B N; Christen, S; Shigenaga, M K
2001 Dec 1;31(11):1375-1387, Free radical biology & medicine
— id: 83139, year: 2001, vol: 31, page: 1375, stat: Journal Article,

Loss of heterozygosity at the mannose 6-phosphate insulin-like growth factor 2 receptor (M6P/IGF2R) locus predisposes patients to radiation-induced lung injury
Kong, F M; Anscher, M S; Sporn, T A; Washington, M K; Clough, R; Barcellos-Hoff, M H; Jirtle, R L
2001 Jan 1;49(1):35-41, International journal of radiation oncology biology physics
— id: 83129, year: 2001, vol: 49, page: 35, stat: Journal Article,

Progesterone receptor signaling controls MMP activities in mouse mammary glands
Simian, M; Barcellos-Hoff, MH; Bissell, MJ; Harris, GS
2001 ;12(1):1090-1090, Molecular biology of the cell
— id: 104685, year: 2001, vol: 12, page: 1090, stat: Journal Article,

Transforming growth factor-beta and breast cancer: Mammary gland development
Barcellos-Hoff, M H; Ewan, K B
2000 ;2(2):92-99, Breast cancer research
— id: 83130, year: 2000, vol: 2, page: 92, stat: Journal Article,

Irradiated mammary gland stroma promotes the expression of tumorigenic potential by unirradiated epithelial cells
Barcellos-Hoff, M H; Ravani, S A
2000 Mar 1;60(5):1254-1260, Cancer research
— id: 83119, year: 2000, vol: 60, page: 1254, stat: Journal Article,

Particle irradiation induces FGF2 expression in normal human lens cells
Chang, P Y; Bjornstad K, A; Chang, E; McNamara, M; Barcellos-Hoff, M H; Lin, S P; Aragon, G; Polansky, J R; Lui, G M; Blakely, E A
2000 Nov;154(5):477-484, Radiation research
— id: 83127, year: 2000, vol: 154, page: 477, stat: Journal Article,

Quantitative image analysis of laminin immunoreactivity in skin basement membrane irradiated with 1 GeV/nucleon iron particles
Costes, S; Streuli, C H; Barcellos-Hoff, M H
2000 Oct;154(4):389-397, Radiation research
— id: 83126, year: 2000, vol: 154, page: 389, stat: Journal Article,

The mammary phenotype of TGF-beta 1 null heterozygotes indicates that TGF-beta actively restrains ovarian steroid hormone-induced proliferation
Ewan, KB; Wakefield, L; Shyamala, WG; Barcellos-Hoff, MH
2000 ;11(4):140-140, Molecular biology of the cell
— id: 104686, year: 2000, vol: 11, page: 140, stat: Journal Article,

Three-dimensional (3D) cultures of human mammary epithelial cells treated with low-dose radiation and transforming growth factor-beta (TGF beta) exhibit altered cell-cell and cell-extracellular matrix interactions
Henshall-Powell, RL; Park, CC; Bissell, MJ; Barcellos-Hoff, MH
2000 ;11(4):2485-2485, Molecular biology of the cell
— id: 104687, year: 2000, vol: 11, page: 2485, stat: Journal Article,

The influence of the microenvironment on the malignant phenotype
Park, C C; Bissell, M J; Barcellos-Hoff, M H
2000 Aug;6(8):324-329, Molecular medicine today
— id: 83124, year: 2000, vol: 6, page: 324, stat: Journal Article,

Low-dose ionizing radiation and transforming growth factor-beta (TGF-beta) are synergistic in altering interactions of human mammary epithelial cells with basement membrane (BM) cultured in a 3-dimensional (3D) matrix
Park, Catherine C.; Wang, Fei; Bissell, Mina J.; Barcellos-Hoff, Mary Helen
2000 ;6(41):376-376, Proceedings (American Association for Cancer Research)
— id: 104688, year: 2000, vol: 6, page: 376, stat: Journal Article,

BioSig: a bioinformatic system for studying the mechanism of inter-cell signaling
Parvin, B.; Cong, G.; Fontenay, G.; Taylor, J.; Henshall, R.; Barcellos-Hoff, M.H.
IEEE International Symposium on Bio-Informatics and Biomedical Engineering Los Alamitos, Ca. : IEEE Computer Society, 2000,
— id: 5231, year: 2000, vol: , page: ?, stat: Chapter,

Modification of multiple pathways revert the malignant phenotype of metastatic mammary carcinoma cells MDA-MB-231
Wang, Fei; Boudreau, Rosanne M.; Yoneda, Toshiyuki; Barcellos-Hoff, Mary Helen; Bissell, Mina J.
2000 ;6(41):473-473, Proceedings (American Association for Cancer Research)
— id: 104689, year: 2000, vol: 6, page: 473, stat: Journal Article,

Characterization of nitrosated latency-associated peptide (LAP), the endogenous neutralizer of the iNOS-inhibitor cytokine transforming growth factor-beta1 (TGF-beta1)
Zamora, Ruben; Wink, David; Barcellos-Hoff, Mary Helen; Billiar, Timothy R.; Vodovotz, Yoram
2000 ;4(3):313-313, Nitric oxide : biology & chemistry
— id: 104690, year: 2000, vol: 4, page: 313, stat: Journal Article,

Immunocytochemical localization of latent transforming growth factor-beta1 activation by stimulated macrophages
Chong, H; Vodovotz, Y; Cox, G W; Barcellos-Hoff, M H
1999 Mar;178(3):275-283, Journal of cellular physiology
— id: 83328, year: 1999, vol: 178, page: 275, stat: Journal Article,

Radiation-induced alterations in rat mesangial cell Tgfb1 and Tgfb3 gene expression are not associated with altered secretion of active Tgfb isoforms
O'Malley, Y; Zhao, W; Barcellos-Hoff, M H; Robbins, M E
1999 Dec;152(6):622-628, Radiation research
— id: 83118, year: 1999, vol: 152, page: 622, stat: Journal Article,

DeepView: a channel for distributed microscopy and informatics
Parvin, B.; Taylor, J.; Cong, G.; O'Keefe, M.A.; Barcellos-Hoff, M.H.
SC 99 : proceedings of the ACM/IEEE SC99 Conference on high performance networking and computing [New York, NY] : ACM, 1999,
— id: 5232, year: 1999, vol: , page: ?, stat: Chapter,

Ionizing radiation accelerates aortic lesion formation in fat-fed mice via SOD-inhibitable processes
Tribble, D L; Barcellos-Hoff, M H; Chu, B M; Gong, E L
1999 Jun;19(6):1387-1392, Arteriosclerosis, thrombosis, & vascular biology
— id: 83114, year: 1999, vol: 19, page: 1387, stat: Journal Article,

Regulation of transforming growth factor beta1 by nitric oxide
Vodovotz, Y; Chesler, L; Chong, H; Kim, S J; Simpson, J T; DeGraff, W; Cox, G W; Roberts, A B; Wink, D A; Barcellos-Hoff, M H
1999 May 1;59(9):2142-2149, Cancer research
— id: 83112, year: 1999, vol: 59, page: 2142, stat: Journal Article,

Modulation of protein expression and activity by radiation: relevance to intracoronary radiation for the prevention of restenosis
Vodovotz, Y; Mitchell, J B; Lucia, M S; McKinney, L; Kollum, M; Cottin, Y; Chan, R C; Barcellos-Hoff, M H; Waksman, R
1999 Oct-Dec;1(4):336-343, Cardiovascular radiation medicine
— id: 83122, year: 1999, vol: 1, page: 336, stat: Journal Article,

Combinatorial modifications of multiple pathways reverts the malignant phenotype or mammary carcinoma cells MDA-MB-231
Wang, F; Yoneda, T; Barcellos-Hoff, MH; Bissell, MJ
1999 ;10(9):2024-2024, Molecular biology of the cell
— id: 104691, year: 1999, vol: 10, page: 2024, stat: Journal Article,

How do tissues respond to damage at the cellular level? The role of cytokines in irradiated tissues
Barcellos-Hoff, M H
1998 Nov;150(5 Suppl):S109-S120, Radiation research
— id: 83325, year: 1998, vol: 150, page: S109, stat: Journal Article,

The potential influence of radiation-induced microenvironments in neoplastic progression
Barcellos-Hoff, M H
1998 Apr;3(2):165-175, Journal of mammary gland biology & neoplasia
— id: 83121, year: 1998, vol: 3, page: 165, stat: Journal Article,

Carcinogen-induced microenvironment in breast cancer
Barcellos-Hoff, Mary
[S.l. : University of California at Berkeley, 1998,
— id: 2091, year: 1998, vol: , page: , stat: ,

A monoclonal antibody for 3-nitrotyrosine: Protein nitration is elevated in liver nonparenchymal cells
Shigenaga, MK; Girault, I; Karu, AE; Barcellos-Hoff, MH; Ames, BN
1998 ;25(5):187-187, Free radical biology & medicine
— id: 104692, year: 1998, vol: 25, page: 187, stat: Journal Article,

Transgenic mice carrying an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands
Shyamala, G; Yang, X; Silberstein, G; Barcellos-Hoff, M H; Dale, E
1998 Jan 20;95(2):696-701, Proceedings of the National Academy of Sciences of the United States of America
— id: 83320, year: 1998, vol: 95, page: 696, stat: Journal Article,

Activation of latent transforming growth factor-beta1 by oxidative and nirosative stress: Role of heme, nitroxyl anion, and nitric oxide
Vodovotz, Y.; Chesler, L.; Simpson, J. L.; Chong, H.; Kim, S.-J.; Cox, G.; Degraff, W.; Roberts, A. B.; Barcellos-Hoff, M. H.; Wink, D. A.
1998 ;2(2):114-114, Nitric oxide : biology & chemistry
— id: 104693, year: 1998, vol: 2, page: 114, stat: Journal Article,

Latent transforming growth factor beta1 activation in situ: quantitative and functional evidence after low-dose gamma-irradiation
Ehrhart, E J; Segarini, P; Tsang, M L; Carroll, A G; Barcellos-Hoff, M H
1997 Oct;11(12):991-1002, FASEB journal
— id: 83319, year: 1997, vol: 11, page: 991, stat: Journal Article,

Immunohistochemical localization of transforming growth factor beta and tumor necrosis factor alpha in the lungs of fibrosis-prone and "non-fibrosing" mice during the latent period and early phase after irradiation
Franko, A J; Sharplin, J; Ghahary, A; Barcellos-Hoff, M H
1997 Feb;147(2):245-256, Radiation research
— id: 83312, year: 1997, vol: 147, page: 245, stat: Journal Article,

Transforming growth factor-beta in breast cancer: a working hypothesis
Reiss, M; Barcellos-Hoff, M H
1997 Aug;45(1):81-95, Breast cancer research & treatment
— id: 83317, year: 1997, vol: 45, page: 81, stat: Journal Article,

Zymosan peritonitis and NO-X-induced nitration
Shigenaga, M. K.; Girault, I.; Christen, S.; Barcellos-Hoff, M. E.; Shigeno, E.; Chang, H.; Ames, B. N.
1997 ;75(SUPPL. 1):74P-74P, Japanese Journal of Pharmacology
— id: 104694, year: 1997, vol: 75, page: 74P, stat: Journal Article,

In situ localization of progesterone receptors in normal mouse mammary glands: absence of receptors in the connective and adipose stroma and a heterogeneous distribution in the epithelium
Shyamala, G; Barcellos-Hoff, M H; Toft, D; Yang, X
1997 Nov-Dec;63(4-6):251-259, Journal of steroid biochemistry & molecular biology
— id: 83321, year: 1997, vol: 63, page: 251, stat: Journal Article,

Ionizing radiation accelerates aortic lesion formation in fat-fed mice via a mechanism that is inhibited by overexpression of Cu/Zn superoxide dismutase
Tribble, Diane L.; Barcellos-Hoff, Mary H.; Rubin, Edward M.; Leeuwenburgh, Christian; Heinecke, Jay W.; Gong, Elaine L.
1997 ;96(8 SUPPL.):I416-I416, Circulation
— id: 104695, year: 1997, vol: 96, page: I416, stat: Journal Article,

Latency and activation in the control of TGF-beta
Barcellos-Hoff, M H
1996 ;1(4):353-363, Journal of mammary gland biology & neoplasia
— id: 116251, year: 1996, vol: 1, page: 353, stat: Journal Article,

Latency and activation in the control of TGF-beta
Barcellos-Hoff, M H
1996 Oct;1(4):353-363, Journal of mammary gland biology & neoplasia
— id: 150855, year: 1996, vol: 1, page: 353, stat: Journal Article,

Redox-mediated activation of latent transforming growth factor-beta 1
Barcellos-Hoff, M H; Dix, T A
1996 Sep;10(9):1077-1083, Molecular endocrinology
— id: 83310, year: 1996, vol: 10, page: 1077, stat: Journal Article,

Effects of nitric oxide on the production of transforming growth factor beta-1 by tumor cells
Chesler, Louis; Cox, George; Barcellos-Hoff, Mary Helen; Wolf, Jeffrey; Takeguchi, Heather; Roberts, Anita; Kim, Seong-Jin; Vodovotz, Yoram
1996 ;37(0):42-43, Proceedings (American Association for Cancer Research)
— id: 104696, year: 1996, vol: 37, page: 42, stat: Journal Article,

Immunohistochemical evidence of rapid extracellular matrix remodeling after iron-particle irradiation of mouse mammary gland
Ehrhart, E J; Gillette, E L; Barcellos-Hoff, M H
1996 Feb;145(2):157-162, Radiation research
— id: 83308, year: 1996, vol: 145, page: 157, stat: Journal Article,

TGF-beta activation in situ: Role in extracellular matrix remodeling
Ehrhart, E. J.; Segarini, P.; Tsang, M. L.-S.; Barcellos-Hoff, M. H.
1996 ;7(SUPPL.):410A-410A, Molecular biology of the cell
— id: 104697, year: 1996, vol: 7, page: 410A, stat: Journal Article,

Immunohistochemical detection of active transforming growth factor-beta in situ using engineered tissue
Barcellos-Hoff, M H; Ehrhart, E J; Kalia, M; Jirtle, R; Flanders, K; Tsang, M L
1995 Nov;147(5):1228-1237, American journal of pathology
— id: 83290, year: 1995, vol: 147, page: 1228, stat: Journal Article,

REDOX MEDIATED LATENT TGF-BETA ACTIVATION
BARCELLOSHOFF, MH
1995 ;9(3):A125-A125, FASEB journal
— id: 104698, year: 1995, vol: 9, page: A125, stat: Journal Article,

Transforming growth factor-beta activation in irradiated murine mammary gland
Barcellos-Hoff, M H; Derynck, R; Tsang, M L; Weatherbee, J A
1994 Feb;93(2):892-899, Journal of clinical investigation
— id: 83299, year: 1994, vol: 93, page: 892, stat: Journal Article,

Multicellular reorganization by single cells on extracellular matrix
Barcellos-Hoff, M. H.
1994 ;30A(3 PART 2):48-48, In vitro cellular & developmental biology. Animal
— id: 104699, year: 1994, vol: 30A, page: 48, stat: Journal Article,

Redox mechanism for activation of latent TGF-beta
Barcellos-Hoff, M. H.
1994 ;5(SUPPL.):139A-139A, Molecular biology of the cell
— id: 104700, year: 1994, vol: 5, page: 139A, stat: Journal Article,

Radiation-induced transforming growth factor beta and subsequent extracellular matrix reorganization in murine mammary gland
Barcellos-Hoff, M H
1993 Sep 1;53(17):3880-3886, Cancer research
— id: 83305, year: 1993, vol: 53, page: 3880, stat: Journal Article,

Immunohistochemical discrimination of active versus latent TGF beta in situ
Barcellos-Hoff, M. H.
1993 ;4(SUPPL.):294A-294A, Molecular biology of the cell
— id: 104701, year: 1993, vol: 4, page: 294A, stat: Journal Article,

Development and functional differentiation of cultured mammary epithelial cells
Aggeler, Judith; Barcellos-Hoff, Mary Helen; Bissell, Mina J.
1992 ;4(SUPPL.):21-33, Contemporary Issues in Clinical Nutrition
— id: 104702, year: 1992, vol: 4, page: 21, stat: Journal Article,

IONIZING RADIATION INDUCED WOUNDING LEADS TO ALTERED STROMAL EXPRESSION OF TRANSFORMING GROWTH FACTOR-BETA IN-VIVO
BARCELLOS-HOFF M H
1992 ;4(16 PART F):78-78, Journal of cellular biochemistry. Supplement
— id: 104703, year: 1992, vol: 4, page: 78, stat: Journal Article,

Mammary epithelial reorganization on extracellular matrix is mediated by cell surface galactosyltransferase
Barcellos-Hoff, M H
1992 Jul;201(1):225-234, Experimental cell research
— id: 83205, year: 1992, vol: 201, page: 225, stat: Journal Article,

Production of stable phenotypes from 9L rat brain tumor multicellular spheroids treated with 1,3-bis(2-chloroethyl)-1-nitrosourea
Barcellos-Hoff, M H; Linfoot, P A; Marton, L J; Deen, D F
1992 Sep 30;52(3):409-413, International journal of cancer
— id: 83171, year: 1992, vol: 52, page: 409, stat: Journal Article,

ACTIVATION OF TRANSFORMING GROWTH FACTOR-BETA-1 (TGF-BETA) AND STROMAL EXTRACELLULAR-MATRIX REMODELING ARE INDUCED BY RADIATION
BARCELLOSHOFF, MH
1992 ;3(3):A29-A29, Molecular biology of the cell
— id: 104704, year: 1992, vol: 3, page: A29, stat: Journal Article,

Cytodifferentiation of mouse mammary epithelial cells cultured on a reconstituted basement membrane reveals striking similarities to development in vivo
Aggeler, J; Ward, J; Blackie, L M; Barcellos-Hoff, M H; Streuli, C H; Bissell, M J
1991 Jun;99 ( Pt 2):407-417, Journal of cell science
— id: 83268, year: 1991, vol: 99 ( Pt 2), page: 407, stat: Journal Article,

The extracellular matrix
Talhouk, Rabih S.; Streuli, Charles H.; Barcellos-Hoff, Mary Helen; Bissell, Mina J.
Structural biology Greenwich, CT : JAI Press, 1991,
— id: 5233, year: 1991, vol: , page: 137, stat: Chapter,

MAMMARY ALVEOLAR-LIKE REORGANIZATION ON RECONSTITUTED BASEMENT MEMBRANE MATRIX IS GALACTOSYLTRANSFERASE DEPENDENT
BARCELLOS-HOFF M H
1990 ;111(5 PART 2):12A-12A, Journal of cell biology
— id: 104706, year: 1990, vol: 111, page: 12A, stat: Journal Article,

DEVELOPMENT OF THIN GELS CONTAINING VIRAL DNA FOR DETERMINATIONS OF STRAND-BREAK INDUCTION BY ULTRASOFT X-RAYS
BARCELLOS-HOFF M H; SHIRLEY G V; CHATTERJEE A
1990 ;99(14 PART A):71-71, Journal of cellular biochemistry. Supplement
— id: 104705, year: 1990, vol: 99, page: 71, stat: Journal Article,

Differential drug sensitivity conferred by growth status detected in a mixed population of cycling and noncycling cells
Barcellos-Hoff, M H; Marton, L J; Deen, D F
1990 Jun 15;50(12):3551-3555, Cancer research
— id: 83272, year: 1990, vol: 50, page: 3551, stat: Journal Article,

Mammary Epithelial Cells As A Model For Studies Of The Regulation Of Gene Expression
Barcellos-hoff MH; Bissell MJ
Functional epithelial cells in culture New York : Liss, 1989,
— id: 5235, year: 1989, vol: , page: 399, stat: Chapter,

Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane
Barcellos-Hoff, M H; Aggeler, J; Ram, T G; Bissell, M J
1989 Feb;105(2):223-235, Development
— id: 83275, year: 1989, vol: 105, page: 223, stat: Journal Article,

Measurement of sister chromatid exchanges and their relationship to DNA damage, repair and cell killing
Deen, D F; Morgan, W F; Tofilon, P J; Barcellos-Hoff, M H
1989 ;42(3):349-360, Pharmacology & therapeutics
— id: 83273, year: 1989, vol: 42, page: 349, stat: Journal Article,

COMPARTMENTALIZATION AND VECTORIAL SECRETION OF MILK PROTEINS BY PRIMARY MAMMARY EPITHELIAL CELLS CULTURED ON RECONSTITUTED BASEMENT MEMBRANE
BARCELLOS-HOFF M H; RAM T G; AGGELER J; BISSELL M J
1988 ;107(6 PART 3):795A-795A, Journal of cell biology
— id: 104707, year: 1988, vol: 107, page: 795A, stat: Journal Article,

Cell-cycle, phase-specific cell killing by carmustine in sensitive and resistant cells
Linfoot, P A; Barcellos-Hoff, M H; Brent, T P; Marton, L J; Deen, D F
1988 ;(6):183-186, NCI monographs
— id: 83277, year: 1988, vol: , page: 183, stat: Journal Article,

POLARIZED SECRETION BY MAMMARY EPITHELIAL CELL CULTURES ON EHS-MATRIX
BARCELLOS-HOFF M H; NEVILLE P N; AGGELER J; BISSELL M J
1987 ;105(4 PART 2):220A-220A, Journal of cell biology
— id: 104708, year: 1987, vol: 105, page: 220A, stat: Journal Article,

The influence of extracellular matrix on gene expression: is structure the message?
Bissell, M J; Barcellos-Hoff, M H
1987 ;8:327-343, Journal of cell science. Supplement
— id: 83276, year: 1987, vol: 8, page: 327, stat: Journal Article,

Transferrin is a major mouse milk protein and is synthesized by mammary epithelial cells
Lee, E Y; Barcellos-Hoff, M H; Chen, L H; Parry, G; Bissell, M J
1987 Mar;23(3):221-226, In vitro cellular & developmental biology
— id: 83278, year: 1987, vol: 23, page: 221, stat: Journal Article,

A SCANNING ELECTRON MICROSCOPE STUDY OF THE MORPHOGENESIS OF MOUSE MAMMARY CULTURES ON COLLAGEN GELS AND EHS MATRIX
NEVILLE M C; STAHL L; LUTES V; BISSELL M J; BARCELLOS-HOFF M H
1987 ;105(4 PART 2):139A-139A, Journal of cell biology
— id: 104709, year: 1987, vol: 105, page: 139A, stat: Journal Article,

Cycling and noncycling cancer cells : expression of differential sensitivity to 1,3 bis(2-chloroethyl)-1-nitrosourea (BCNU) and X-rays
Barcellos-Hoff, Mary Helen
[S.l. : s.n.], 1986,
— id: 2093, year: 1986, vol: , page: , stat: ,

"DIFFERENTIAL INDUCTION OF SISTER CHROMATID EXCHANGE (SCE) BY ""1,3BIS-(2CHLOROETHYL)-1-NITROSOUREA (BCNU) IN CYCLING AND NONCYCLING CELLS OF 9L SPHEROIDS"
BARCELLOSHOFF, MH; MARTON, LJ; DEEN, DF
1986 ;27(4 PART 2):386-386, Proceedings (American Association for Cancer Research)
— id: 104710, year: 1986, vol: 27, page: 386, stat: Journal Article,

CELL CYCLE CHARACTERISTICS OF 9L SPHEROIDS DETERMINED FLOW CYTOMETRICALLY WITH MONOCLONAL ANTIBODIES TO BROMODEOXYURIDINE-SUBSTITUTED DNA
BARCELLOS-HOFF M H; GRAY J W; MARTON L J; DEEN D F
1985 ;101(5 PART 2):322A-322A, Journal of cell biology
— id: 104711, year: 1985, vol: 101, page: 322A, stat: Journal Article,

Growth delay in 9L rat brain tumor spheroids after irradiation with single and split doses of X rays
Jostes, R F; Williams, M E; Barcellos-Hoff, M H; Hoshino, T; Deen, D F
1985 May;102(2):182-189, Radiation research
— id: 83283, year: 1985, vol: 102, page: 182, stat: Journal Article,

The effect of combination treatment with cis-platinum and low dose rate 125I radiation in a murine brachytherapy model
da Silva, V; Gutin, P H; Barcellos-Hoff, M H; Bernstein, M A; Deen, D F; Weaver, K A
1984 Aug;10(8):1471-1472, International journal of radiation oncology biology physics
— id: 83285, year: 1984, vol: 10, page: 1471, stat: Journal Article,

Radiosensitization of the RIF-1 murine flank tumor by desmethylmisonidazole (Ro 05 9963) during interstitial brachytherapy
Bernstein, M; Gutin, P H; Deen, D F; Weaver, K A; Levin, V A; Barcellos, M H
1982 Mar-Apr;8(3-4):487-490, International journal of radiation oncology biology physics
— id: 105534, year: 1982, vol: 8, page: 487, stat: Journal Article,

125I interstitial implants in the RIF-1 murine flank tumor: an animal model for brachytherapy
Bernstein, M; Gutin, P H; Weaver, K A; Deen, D F; Barcellos, M H
1982 Sep;91(3):624-637, Radiation research
— id: 105533, year: 1982, vol: 91, page: 624, stat: Journal Article,

Further evidence for the absence of a hypoxic fraction in the 9L rat tumour multicellular spheroid system
Gutin, P H; Barcellos, M H; Shrieve, D C; Sano, Y; Bernstein, M; Deen, D F
1982 Sep;55(657):688-690, British journal of radiology
— id: 105532, year: 1982, vol: 55, page: 688, stat: Journal Article,