Leon Axel

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Leon Axel

Professor, Department of Radiology;Professor, Department of Medicine;Professor, Department of Neuroscience and Physiology
Radiology
NYU Radiology Associates

Contact Info

Address
660 First Avenue
New York, NY 10016

212/263-6248

Research Summary

Heart disease, particularly related to ischemia and infarction, remains the principal cause of morbidity and death in the Western World. MRI and CT have the potential of playing significant roles in the evaluation of the heart, both for research and clinical applications.

The Cardiac Imaging and Analysis Laboratory (CARDIAL), under the direction of Leon Axel, is a multidisciplinary group dedicated to the development and evaluation of new cardiac imaging methods, particularly those involving quantitative characterization of such physiologic aspects as function and perfusion. This includes development of novel MRI cardiac imaging methods such as tagged MRI for regional cardiac function analysis and rapid quantitative imaging for perfusion studies, and associated programs for image analysis, as well as research on their basic and clinical applications.

Research Interests

Cardiac MRI, including MR image acquisition and image analysis methods development and applications to studies of cardiac physiology and pathophysiology

XD-GRASP: Golden-angle radial MRI with reconstruction of extra motion-state dimensions using compressed sensing
Feng, Li; Axel, Leon; Chandarana, Hersh; Block, Kai Tobias; Sodickson, Daniel K; Otazo, Ricardo. XD-GRASP: Golden-angle radial MRI with reconstruction of extra motion-state dimensions using compressed sensing. Magnetic resonance in medicine. 2015 Mar;:775-788 CD010743 (1514172)

Assessment of Septal Motion Abnormalities in Left Bundle Branch Block Patients Using Computer Simulations
Huntjens, P.R.; Walmsley, J.; Wu, V.; Delhaas, T.; Axel, L.; Lumens, J.. Assessment of Septal Motion Abnormalities in Left Bundle Branch Block Patients Using Computer Simulations IN: Functional imaging and modeling of the heart : 8th International Conference, FIMH 2015, Maastricht, The Netherlands, June 25-27, 2015. Proceedings. New York : Springer Verlag, 2015. p.40-47 (LNCS sublibrary. SL 6, Image processing, computer vision, pattern recognition, and graphics) (1701942)

Preliminary Assessment of Tricuspid Valve Annular Velocity Parameters by Cardiac Magnetic Resonance Imaging in Adults with a Volume-Overloaded Right Ventricle: Comparison of Unrepaired Atrial Septal Defect and Repaired Tetralogy of Fallot
Ito, Seiji; McElhinney, Doff B; Adams, Robert; Bhatla, Puneet; Chung, Sohae; Axel, Leon. Preliminary Assessment of Tricuspid Valve Annular Velocity Parameters by Cardiac Magnetic Resonance Imaging in Adults with a Volume-Overloaded Right Ventricle: Comparison of Unrepaired Atrial Septal Defect and Repaired Tetralogy of Fallot. Pediatric cardiology. 2015 Apr;36(6):1294-1300 pdb.prot081372 (1519622)

Diagnostic Performance of Cardiac Magnetic Resonance Imaging and Echocardiography in Evaluation of Cardiac and Paracardiac Masses
Patel, Rima; Lim, Ruth P; Saric, Muhamed; Nayar, Ambika; Babb, James; Ettel, Mark; Axel, Leon; Srichai, Monvadi B. Diagnostic Performance of Cardiac Magnetic Resonance Imaging and Echocardiography in Evaluation of Cardiac and Paracardiac Masses. American journal of cardiology. 2015 Oct;:135-140 (1834702)

Clearance systems in the brain-implications for Alzheimer disease
Tarasoff-Conway, Jenna M; Carare, Roxana O; Osorio, Ricardo S; Glodzik, Lidia; Butler, Tracy; Fieremans, Els; Axel, Leon; Rusinek, Henry; Nicholson, Charles; Zlokovic, Berislav V; Frangione, Blas; Blennow, Kaj; Menard, Joel; Zetterberg, Henrik; Wisniewski, Thomas; de Leon, Mony J. Clearance systems in the brain-implications for Alzheimer disease. Nature reviews. Neurology. 2015 Jul;:457-470 (1683822)