Christopher W. Aston

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Christopher W. Aston, Ph.D.

Adjunct Assistant Professor;
Department of Medicine (Pulmy&CCM Div)

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Education

— Dr. Aston received his D.Phil (PhD) in 1991 from The University of Oxford, UK, in Cellular and Molecular Biology. His doctoral research was on the role of advanced glycosylation endproduct-modified proteins in diabetic complications and aging, Graduate Education
— University of Oxford, Medical Education

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Research Summary

Dr. Aston is Chief of Molecular Biology at the NYC Dept. Health Biothreat Response Laboratory. This reference lab has the capacity to detect and identify a full range of biological agents and potential biological weapons of mass destruction. The lab tests samples from law enforcement agencies and specimens from clinical sources. The facility has approximately 20,000 square feet of laboratory space, much of it upgraded to Bio-Safety Level 3 (BSL-3). The lab is funded through the City's capital budget with additional operating support from a federal bioterrorism readiness and response grant from the Centers for Disease Control and Prevention (CDC). Dr. Aston is licensed as a clinical laboratory director by the New York State Clinical Laboratory Evaluation Program and a technical laboratory director by the New York State Environmental Laboratory Approval Program.

Research Keywords

alveolar macrophages, mycobacteria, phagocytes, protein tyrosine kinases, tuberculosis

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All data from NYU Health Sciences Library Faculty Bibliography — -

Contact:
http://hsl.med.nyu.edu/faculty-bibliography-search

Public health and environmental response to the first case of naturally acquired inhalational anthrax in the United States in 30 years: infection of a new york city resident who worked with dried animal hides
Nguyen, Trang Quyen; Clark, Nancy; Karpati, Adam; Goldberg, Allan; Paykin, Andrea; Tucker, Andrew; Baker, Angela; Almiroudis, Anna; Fine, Annie; Tsoi, Ben; Aston, Christopher; Berg, Debra; Weiss, Don; Connelly, Ed; Beaudry, Gary; Weisfuse, Isaac; Durrah, James C; Prudhomme, Jeanine; Leighton, Jessica; Ackelsberg, Joel; Mahoney, Kevin; Van Vynck, Laurie; Lee, Lillian; Moskin, Linda; Layton, Marci; Wong, Marie; Raphael, Marisa; Robinson, Martha; Phillips, Michael; Jones, Mickey; Jeffery, Nancy; Nieves, Ray; Slavinski, Sally; Mullin, Sandra; Beatrice, Sara T; Balter, Sharon; Blank, Sue; Frieden, Thomas; Keifer, Max; Rosenstein, Nancy; Diaz, Pamela; Clark, Thomas; Compton, Harry; Daloia, James; Cardarelli, John; Norrell, Neil; Horn, Ed; Jackling, Sam; Bacon, Connie; Glasgow, Erich; Gomez, Tom; Baltzersen, Richard A; Kammerdener, Charles; Margo-Zavazky, Dani; Colgan, John; Pulaski, Phillip
2010 May-Jun;16(3):189-200, Journal of public health management & practice
— id: 831582, year: 2010, vol: 16, page: 189, stat: Journal Article,

Laboratory testing in response to anthrax contamination in New York city, 2006
Aston, Christopher; Lee, L.; Wong, M. T.; Beaudry, G.; Meyer, F.; Beatrice, S. T.
2007 ;107:718-718, Abstracts of the ... general meeting of the American Society for Microbiology
— id: 831592, year: 2007, vol: 107, page: 718, stat: Journal Article,

Inhalation anthrax associated with dried animal hides - Pennsylvania and New York City, 2006 (Reprinted from MMWR, vol 55, pg 280-282, 2006)
Walsh, J; Fraser, G; Hunt, E; Husband, B; Nalluswami, K; Pollard, K; Reynolds, S; Urdaneta, V; Weltman, A; Aston, Christopher; Balter, S; Beatrice, S; Beaudry, G; Berg, D; Clark, N; Frieden, T; Karpati, A; Layton, M; Lee, L; Leighton, J; Moskin, L; Mullin, S; Phillips, M; Paykin, A; Prud'homme, J; Slavinski, S; Tucker, A; Weisfuse, I; Weis, D; Wolsk, G; Bacon, C; Glasgow, E; Gomez, T; Swartz, W; Baden, D; Clark, T; Dauphin, LA; Diaz, P; Dykewicz, CA; Fleischauer, A; Frank, M; Gee, JE; Hoffmaster, A; Kim, H; Marston, C; Meyer, R; McQuiston, J; Newton, B; Papagiotqas, S; Pesik, N; Piester, T; Quinn, C; Reagan, S; Rotz, L; Rosenberg, P; Rosenstein, N; Shadomy, S; Semanova, V; Treadwell, T; Wilkins, P; Winchell, J; Burr, G; Dowell, C; Hornsby-Myers, J; Kiefer, M; King, B; Nguyen, TQ; Arboleda, N; Tsoi, B
2006 MAY 3;295(17):1991-1993, JAMA
— id: 831602, year: 2006, vol: 295, page: 1991, stat: Journal Article,

Neither snow, nor rain, nor anthrax - To counter bioterrorism, the US Postal Service tries irradiation, then detection, and maybe soon smart mail
Aston, Christopher
2002 SEP;39(9):38-39, IEEE spectrum
— id: 831612, year: 2002, vol: 39, page: 38, stat: Journal Article,

Biological warfare canaries
Aston, Christopher
2001 OCT;38(10):35-40, IEEE spectrum
— id: 831572, year: 2001, vol: 38, page: 35, stat: Journal Article,

Early inhibition of mycobacterial growth by human alveolar macrophages is not due to nitric oxide
Aston C; Rom WN; Talbot AT; Reibman J
1998 Jun;157(6 Pt 1):1943-1950, American journal of respiratory & critical care medicine
— id: 7492, year: 1998, vol: 157, page: 1943, stat: Journal Article,

Immunohistochemical localization of transforming growth factor beta isoforms in asbestos-related diseases
Jagirdar J; Lee TC; Reibman J; Gold LI; Aston C; Begin R; Rom WN
1997 Sep;105 Suppl 5:1197-1203, Environmental health perspectives
— id: 12204, year: 1997, vol: 105 Suppl 5, page: 1197, stat: Journal Article,

Effects of mycobacteria on regulation of apoptosis in mononuclear phagocytes
Klingler K; Tchou-Wong KM; Brandli O; Aston C; Kim R; Chi C; Rom WN
1997 Dec;65(12):5272-5278, Infection & immunity
— id: 56887, year: 1997, vol: 65, page: 5272, stat: Journal Article,

Immunohistochemical localization of transforming growth factor-beta and insulin-like growth factor-I in asbestosis in the sheep model
Lee TC; Gold LI; Reibman J; Aston C; Begin R; Rom WN; Jagirdar J
1997 ;69(3):157-164, International archives of occupational & environmental health
— id: 12416, year: 1997, vol: 69, page: 157, stat: Journal Article,

Elevated interleukin-8 in the alveolitis of individuals with asbestos exposure
Broser M; Zhang Y; Aston C; Harkin T; Rom WN
1996 ;68(2):109-114, International archives of occupational & environmental health
— id: 12690, year: 1996, vol: 68, page: 109, stat: Journal Article,

Enhanced insulin-like growth factor molecules in idiopathic pulmonary fibrosis
Aston C; Jagirdar J; Lee TC; Hur T; Hintz RL; Rom WN
1995 May;151(5):1597-1603, American journal of respiratory & critical care medicine
— id: 6569, year: 1995, vol: 151, page: 1597, stat: Journal Article,

THE ROLE OF INSULIN-LIKE GROWTH-FACTOR MOLECULES IN IDIOPATHIC PULMONARY FIBROSIS (IPF)
ASTON, C; LEE, TC; JAGIRDAR, J; HUR, T; HINTZ, RL; ROM, WN
1993 APR ;147(4):A481-A481, American review of respiratory disease
— id: 54158, year: 1993, vol: 147, page: A481, stat: Journal Article,

Normal human mesothelial cells and mesothelioma cell lines express insulin-like growth factor I and associated molecules
Lee TC; Zhang Y; Aston C; Hintz R; Jagirdar J; Perle MA; Burt M; Rom WN
1993 Jun 15;53(12):2858-2864, Cancer research
— id: 57504, year: 1993, vol: 53, page: 2858, stat: Journal Article,

THE ROLE OF IGF-I AND TGF-BETA IN A SHEEP MODEL OF ASBESTOSIS
LEE, TC; JAGIRDAR, J; ASTON, C; REIBMAN, J; GOLD, L; BEGIN, R; ROM, WN
1993 APR ;147(4):A758-A758, American review of respiratory disease
— id: 54167, year: 1993, vol: 147, page: A758, stat: Journal Article,

TRANSFORMING GROWTH-FACTOR-BETA (TGF-BETA) ISOFORMS IN ASBESTOS-RELATED DISEASES
LEE, TC; JAGIRDAR, J; REIBMAN, J; GOLD, L; ASTON, C; BEGIN, R; ROM, WN
1993 APR ;147(4):A759-A759, American review of respiratory disease
— id: 54168, year: 1993, vol: 147, page: A759, stat: Journal Article,