Sylvia Adams, M.D.

Novel combination of toll-like receptor (TLR)-7 agonist imiquimod and local radiotherapy in the treatment of breast cancer chest wall recurrences or skin metastases
Janosky, M D; Demaria, S; Novik, Y; Oratz, R; Tiersten, A; Goldberg, J D; Wang, E; Marincola, F; Formenti, S; Adams, S
2013 20 May 2013;31(15):-, Journal of clinical oncology
— id: 451782, year: 2013, vol: 31, page: , stat: Journal Article,

Clinical cancer advances 2012: annual report on progress against cancer from the american society of clinical oncology
Roth, Bruce J; Krilov, Lada; Adams, Sylvia; Aghajanian, Carol A; Bach, Peter; Braiteh, Fadi; Brose, Marcia S; Ellis, Lee M; Erba, Harry; George, Daniel J; Gilbert, Mark R; Jacobson, Joseph O; Larsen, Eric C; Lichtman, Stuart M; Partridge, Ann H; Patel, Jyoti D; Quinn, David I; Robison, Leslie L; von Roenn, Jamie H; Samlowski, Wolfram; Schwartz, Gary K; Vogelzang, Nicholas J
2013 Jan;31(1):131-161, Journal of clinical oncology
— id: 214312, year: 2013, vol: 31, page: 131, stat: Journal Article,

RAD001-carboplatin combination in triple-negative metastatic breast cancer (TNMBC): A phase II trial
Singh, J C; Stein, S; Volm, M; Smith, J A; Adams, S; Meyers, M; Speyer, J L; Novik, Y; Schneider, R; Formenti, S; Muggia, F; Jhaveri, K L; Goldberg, J D; Heese, S; Li, X; Davis, S; Tiersten, A
2013 20 May 2013;31(15):-, Journal of clinical oncology
— id: 452012, year: 2013, vol: 31, page: , stat: Journal Article,

Pathologic response rate in HER2-positive locally advanced breast cancers treated with neoadjuvant trastuzumab and concurrent paclitaxel/radiotherapy
Adams, S; Hochman, T; Huppert, N; Dhage, S; Checka, C; Singh, B; Speyer, J L; Schneider, R; Goldberg, J D; Formenti, S
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 249962, year: 2012, vol: 30, page: , stat: Journal Article,

Topical TLR7 agonist imiquimod can induce immune-mediated rejection of skin metastases in patients with breast cancer
Adams, S; Kozhaya, L; Martiniuk, F; Meng, TC; Chiriboga, L; Liebes, L; Hochman, T; Shuman, N; Axelrod, D; Speyer, JL; Novik, Y; Tiersten, A; Goldberg, JD; Formenti, SC; Bhardwaj, N; Unutmaz, D; Demaria, S
2012 Jul;:6748-6757, Clinical cancer research
— id: 171476, year: 2012, vol: , page: 6748, stat: Journal Article,

Synergy of Topical Toll-like Receptor 7 Agonist with Radiation and Low-Dose Cyclophosphamide in a Mouse Model of Cutaneous Breast Cancer
Dewan, M Zahidunnabi; Vanpouille-Box, Claire; Kawashima, Noriko; Dinapoli, Sara; Babb, James S; Formenti, Silvia C; Adams, Sylvia; Demaria, Sandra
2012 Dec;18(24):6668-6678, Clinical cancer research
— id: 203832, year: 2012, vol: 18, page: 6668, stat: Journal Article,

Pilot Trial of Radiation Therapy and GM-CSF in Metastatic Cancer: Abscopal Responses
Formenti, S.; Adams, S.; Friedman, K.; Fenton-Kerimian, M.; Donach, M.; Goldberg, J.; Demaria, S.
2012 NOV 1;84(3 S S):S178-S178, International journal of radiation oncology biology physics
— id: 204762, year: 2012, vol: 84, page: S178, stat: Journal Article,

Phase I/II study of resiquimod as an immunologic adjuvant for NY-ESO-1 protein vaccination in patients with melanoma
Sabado, R L; Pavlick, A C; Gnjatic, S; Cruz, C M; Vengco, I; Hasan, F; Darvishian, F; Chiriboga, L; Holman, R M; Escalon, J; Muren, C; Escano, C; Yepes, E; Sharpe, D; Adams, S; Ott, P A; Jungbluth, A A; Pan, L S; Venhaus, R R; Bhardwaj, N
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 250102, year: 2012, vol: 30, page: , stat: Journal Article,

Phase II trial of RAD001 plus carboplatin in patients with triple-negative metastatic breast cancer
Singh, J C; Stein, S; Volm, M; Smith, J A; Novik, Y; Speyer, J L; Meyers, M; Adams, S; Omene, C O; Muggia, F; Schneider, R; Formenti, S; Davis, S; Beardslee, B; Tiersten, A
2012 20 May 2012;30(15):-, Journal of clinical oncology
— id: 249952, year: 2012, vol: 30, page: , stat: Journal Article,

Efficacy of RAD001/carboplatin in triple-negative metastatic breast cancer: A phase II study
Singh, J C; Volm, M; Novik, Y; Speyer, J L; Adams, S; Omene, C O; Meyers, M I; Smith, J A; Schneider, R; Formenti, S; Goldberg, J D; Li, X; Davis, S; Beardslee, B; Tiersten, A
2012 20 Sep 2012;30(27):-, Journal of clinical oncology
— id: 395172, year: 2012, vol: 30, page: , stat: Journal Article,

Clinical cancer advances 2011: Annual Report on Progress Against Cancer from the American Society of Clinical Oncology
Vogelzang, Nicholas J; Benowitz, Steven I; Adams, Sylvia; Aghajanian, Carol; Chang, Susan Marina; Dreyer, Zoann Eckert; Janne, Pasi A; Ko, Andrew H; Masters, Greg A; Odenike, Olatoyosi; Patel, Jyoti D; Roth, Bruce J; Samlowski, Wolfram E; Seidman, Andrew D; Tap, William D; Temel, Jennifer S; Von Roenn, Jamie H; Kris, Mark G
2012 Jan;30(1):88-109, Journal of clinical oncology
— id: 160659, year: 2012, vol: 30, page: 88, stat: Journal Article,

Expression of cancer testis antigens in human BRCA-associated breast cancers: potential targets for immunoprevention?
Adams, Sylvia; Greeder, Luba; Reich, Elsa; Shao, Yongzhao; Fosina, Denise; Hanson, Nicole; Tassello, Jodie; Singh, Baljit; Spagnoli, Giulio C; Demaria, Sandra; Jungbluth, Achim A
2011 Jul;60(7):999-1007, Cancer immunology immunotherapy
— id: 134441, year: 2011, vol: 60, page: 999, stat: Journal Article,

Cross-Talk of Breast Cancer Cells with the Immune System
Demaria, Sandra; Pilones, Karsten A; Adams, Sylvia
Breast Cancer : Carcinogenesis, Cell Growth and Signalling Pathways Rijeka, Croatia : InTech, 2011,
— id: 5837, year: 2011, vol: , page: 469, stat: Chapter,

Role of T-lymphocytes for tumour response to radiotherapy
Formenti S.; Encouse G.; Adams S.; Pilones K.; Grazia Ruocco M.; Dustin M.; Demaria S.
2011 ;47:S11-S11, European journal of cancer (1990)
— id: 138729, year: 2011, vol: 47, page: S11, stat: Journal Article,

The numbers of FoxP3+ lymphocytes in sentinel lymph nodes of breast cancer patients correlate with primary tumor size but not nodal status
Gupta, Raavi; Babb, James S; Singh, Baljit; Chiriboga, Luis; Liebes, Leonard; Adams, Sylvia; Demaria, Sandra
2011 Jul;29(6):419-425, Cancer investigation
— id: 138850, year: 2011, vol: 29, page: 419, stat: Journal Article,

Small-molecule protein kinase inhibitors and their effects on the immune system: implications for cancer treatment
Ott, Patrick A; Adams, Sylvia
2011 Feb;3(2):213-227, Immunotherapy
— id: 123132, year: 2011, vol: 3, page: 213, stat: Journal Article,

CTLA-4 blockade increases antigen-specific CD8(+) T cells in prevaccinated patients with melanoma: three cases
Yuan, Jianda; Ginsberg, Brian; Page, David; Li, Yanyun; Rasalan, Teresa; Gallardo, Humilidad F; Xu, Yinyan; Adams, Sylvia; Bhardwaj, Nina; Busam, Klaus; Old, Lloyd J; Allison, James P; Jungbluth, Achim; Wolchok, Jedd D
2011 Aug;60(8):1137-1146, Cancer immunology immunotherapy
— id: 144815, year: 2011, vol: 60, page: 1137, stat: Journal Article,

Preoperative concurrent paclitaxel-radiation in locally advanced breast cancer: pathologic response correlates with five-year overall survival
Adams, Sylvia; Chakravarthy, A Bapsi; Donach, Martin; Spicer, Darcy; Lymberis, Stella; Singh, Baljit; Bauer, Joshua A; Hochman, Tsivia; Goldberg, Judith D; Muggia, Franco; Schneider, Robert J; Pietenpol, Jennifer A; Formenti, Silvia C
2010 Dec;124(3):723-732, Breast cancer research & treatment
— id: 114178, year: 2010, vol: 124, page: 723, stat: Journal Article,

Clinical cancer advances 2010: annual report on progress against cancer from the American Society of Clinical Oncology
Kris, Mark G; Benowitz, Steven I; Adams, Sylvia; Diller, Lisa; Ganz, Patricia; Kahlenberg, Morton S; Le, Quynh-Thu; Markman, Maurie; Masters, Greg A; Newman, Lisa; Obel, Jennifer C; Seidman, Andrew D; Smith, Sonali M; Vogelzang, Nicholas; Petrelli, Nicholas J
2010 Dec 20;28(36):5327-5347, Journal of clinical oncology
— id: 120617, year: 2010, vol: 28, page: 5327, stat: Journal Article,

Five-year Results of Preoperative Paclitaxel with Concurrent Radiation Therapy in Locally Advanced Breast Cancer: Pathological Response Predicts for Survival
Schneider, R. J.; Formenti, S. C.; Chakravarthy, A.; Adams, S.; Spicer, D.; Lymberis, S.; Goldberg, J. D.; Pietenpol, J. A.
2010 OCT 13 ;78(3):S219-S219, International journal of radiation oncology biology physics
— id: 114016, year: 2010, vol: 78, page: S219, stat: Journal Article,

Lack of Hormone Receptor Expression is Associated with Pathological Response in Locally Advanced Breast Cancer Patients Treated with Neoadjuvant Concurrent Chemoradiation
Adams, S; Donach, M; Singh, B; Goldberg, JD; Formenti, SC
2009 NOV ;75(3):S220-S221, International journal of radiation oncology biology physics
— id: 106177, year: 2009, vol: 75, page: S220, stat: Journal Article,

Toll-like receptor agonists in cancer therapy
Adams, Sylvia
2009 Nov;1(6):949-964, Immunotherapy
— id: 111621, year: 2009, vol: 1, page: 949, stat: Journal Article,

Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival
Bogunovic, Dusan; O'Neill, David W; Belitskaya-Levy, Ilana; Vacic, Vladimir; Yu, Yi-Lo; Adams, Sylvia; Darvishian, Farbod; Berman, Russell; Shapiro, Richard; Pavlick, Anna C; Lonardi, Stefano; Zavadil, Jiri; Osman, Iman; Bhardwaj, Nina
2009 Dec 1;106(48):20429-20434, Proceedings of the National Academy of Sciences of the United States of America
— id: 105312, year: 2009, vol: 106, page: 20429, stat: Journal Article,

Lack of Functionally Active Melan-A(26-35)-Specific T Cells in the Blood of HLA-A2(+) Vitiligo Patients
Adams, Sylvia; Lowes, Michelle A; O'Neill, David W; Schachterle, Stephen; Romero, Pedro; Bhardwaj, Nina
2008 Aug;128(8):1977-1980, Journal of investigative dermatology
— id: 76847, year: 2008, vol: 128, page: 1977, stat: Journal Article,

Immunization of Malignant Melanoma Patients with Full-Length NY-ESO-1 Protein Using TLR7 Agonist Imiquimod as Vaccine Adjuvant
Adams, Sylvia; O'Neill, David W; Nonaka, Daisuke; Hardin, Elizabeth; Chiriboga, Luis; Siu, Kimberly; Cruz, Crystal M; Angiulli, Angelica; Angiulli, Francesca; Ritter, Erika; Holman, Rose Marie; Shapiro, Richard L; Berman, Russell S; Berner, Natalie; Shao, Yongzhao; Manches, Olivier; Pan, Linda; Venhaus, Ralph R; Hoffman, Eric W; Jungbluth, Achim; Gnjatic, Sacha; Old, Lloyd; Pavlick, Anna C; Bhardwaj, Nina
2008 Jul 1;181(1):776-784, Journal of immunology
— id: 79260, year: 2008, vol: 181, page: 776, stat: Journal Article,

Gene expression profile for metastatic melanoma and patient survival
Bogunovic D; O'Neill D; Adams S; Wang J; Darvishian F; Pavlick AC; Shapiro RL; Zavadil J; Osman I; Bhardwaj N
2008 May 20;26(Suppl):?-? #9049, Proceedings (American Society of Clinical Oncology)
— id: 106301, year: 2008, vol: 26, page: ?, stat: Journal Article,

Abscopal response in irradiated patients: Results of a proof of principle trial
Formenti, SC; Friedman, K; Chao, K; Adams, S; Fenton-Kerimian, M; Donach, ME; Demaria, S
2008 AUG ;72(1):S6-S7, International journal of radiation oncology biology physics
— id: 86793, year: 2008, vol: 72, page: S6, stat: Journal Article,

Transfection of dendritic cells (DCs) with mRNA encoding IL-12p70 enhances anti-tumor immunity in melanoma patients
Minkis K; Kavanagh D; O'Neill D; Alter G; Sunderji S; Adams S; Walker B; Pavlick AC; Gandhi R; Bhardwaj N
2008 May 20;26(Suppl):?-? #22217, Proceedings (American Society of Clinical Oncology)
— id: 79466, year: 2008, vol: 26, page: ?, stat: Journal Article,

Type 2 Bias of T cells expanded from the blood of melanoma patients switched to type 1 by IL-12p70 mRNA-transfected dendritic cells
Minkis, Kira; Kavanagh, Daniel G; Alter, Galit; Bogunovic, Dusan; O'Neill, David; Adams, Sylvia; Pavlick, Anna; Walker, Bruce D; Brockman, Mark A; Gandhi, Rajesh T; Bhardwaj, Nina
2008 Nov 15;68(22):9441-9450, Cancer research
— id: 90929, year: 2008, vol: 68, page: 9441, stat: Journal Article,

Dendritic cell vaccines
Adams S; O'Neil DW; Bhardwaj N
General principles of tumor immunotherapy : basic and clinical applications of tumor immunology Dordrecht : Springer, 2007,
— id: 5631, year: 2007, vol: , page: , stat: Chapter,

Imiquimod -- a TLR 7 agonist as vaccine adjuvant
Adams S; O'Neill D; Pavlick A; Hardin E; Nonaka D; Chiriboga L; Siu K; Shapiro R; Berman R; Strober B; Cruz C; Angiulli A; Manchez O; Berner N; Mukhi V; Shao Y; Bhardwaj N
2007 ;:- #8545, Proceedings (American Society of Clinical Oncology)
— id: 73377, year: 2007, vol: , page: , stat: Journal Article,

Vaccination with NY-ESO-1 protein and CpG in Montanide induces integrated antibody/Th1 responses and CD8 T cells through cross-priming
Valmori, Danila; Souleimanian, Naira E; Tosello, Valeria; Bhardwaj, Nina; Adams, Sylvia; O'Neill, David; Pavlick, Anna; Escalon, Juliet B; Cruz, Crystal M; Angiulli, Angelica; Angiulli, Francesca; Mears, Gregory; Vogel, Susan M; Pan, Linda; Jungbluth, Achim A; Hoffmann, Eric W; Venhaus, Ralph; Ritter, Gerd; Old, Lloyd J; Ayyoub, Maha
2007 May 22;104(21):8947-8952, Proceedings of the National Academy of Sciences of the United States of America
— id: 72446, year: 2007, vol: 104, page: 8947, stat: Journal Article,

Expression of the cancer/testis antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM)--correlation with prognostic factors
Velazquez, Elsa F; Jungbluth, Achim A; Yancovitz, Molly; Gnjatic, Sacha; Adams, Sylvia; O'Neill, David; Zavilevich, Kira; Albukh, Tatyana; Christos, Paul; Mazumdar, Madhu; Pavlick, Anna; Polsky, David; Shapiro, Richard; Berman, Russell; Spira, Joanna; Busam, Klaus; Osman, Iman; Bhardwaj, Nina
2007 ;7:11-11, Cancer imunity
— id: 73347, year: 2007, vol: 7, page: 11, stat: Journal Article,

Expression of cancer testis (CT) antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM), correlation with prognostic factors and potential role in a melanoma vaccine
Velazquez, EF; Jungbluth, AA; Osman, I; Yancovitz, M; Adams, S; O'Neill, D; Zavilevich, K; Albukh, T; Pavlick, A; Polsky, D; Shapiro, R; Berman, R; Spira, J; Busam, K; Bhardwaj, N
2006 JAN ;19(4):89A-89A, Modern pathology
— id: 61434, year: 2006, vol: 19, page: 89A, stat: Journal Article,

Expression of cancer testis (CT) antigen NY-ESO-1 in primary and metastatic malignant melanoma (MM), correlation with prognostic factors and potential role in a melanoma vaccine
Velazquez, EF; Jungbluth, AA; Osman, I; Yancovitz, M; Adams, S; O'Neill, D; Zavilevich, K; Albukh, T; Pavlick, A; Polsky, D; Shapiro, R; Berman, R; Spira, J; Busam, K; Bhardwaj, N
2006 JAN ;86(4):89A-89A, Laboratory investigation
— id: 62615, year: 2006, vol: 86, page: 89A, stat: Journal Article,

Spontaneous immune reponses to melanoma-associated antigens in melanoma, vitiligo and healthy controls
Adams S; Lowes M; Pavlick A; Schachterle S; O'Neill D; Bhardwaj N
2005 ;23:16S-16S abstact #9682, Proceedings (American Society of Clinical Oncology)
— id: 60240, year: 2005, vol: 23, page: 16S, stat: Journal Article,

Recent advances in dendritic cell biology
Adams, Sylvia; O'Neill, David W; Bhardwaj, Nina
2005 Mar;25(2):87-98, Journal of clinical immunology
— id: 55977, year: 2005, vol: 25, page: 87, stat: Journal Article,

Recent advances in dendritic cell biology
Adams, Sylvia; O'Neill, David W; Bhardwaj, Nina
2005 May;25(3):177-188, Journal of clinical immunology
— id: 58180, year: 2005, vol: 25, page: 177, stat: Journal Article,

Maturation matters: importance of maturation for antitumor immunity of dendritic cell vaccines
Adams, Sylvia; O'Neill, David; Bhardwaj, Nina
2004 Sep 15;22(18):3834-5; author reply 3835, Journal of clinical oncology
— id: 63123, year: 2004, vol: 22, page: 3834, stat: Journal Article,

Manipulating dendritic cell biology for the active immunotherapy of cancer
O'Neill, David W; Adams, Sylvia; Bhardwaj, Nina
2004 Oct 15;104(8):2235-2246, Blood
— id: 47843, year: 2004, vol: 104, page: 2235, stat: Journal Article,

Pegylated liposomal doxorubicin (PLD) and carboplatin (C): A phase I study of combination therapy with maintenance PLD
Hamilton AL; Pavlick A; Volm M; Adams S; Hochster H; Moore S; Mozina J; Cordner M; Utate M; Muggia F
2003 ;22:2003-2003 #1986, Proceedings (American Society of Clinical Oncology)
— id: 79467, year: 2003, vol: 22, page: 2003, stat: Journal Article,

Novel therapeutic agents under investigation for malignant melanoma
Pavlick, Anna C; Adams, Sylvia; Fink, Matthew A; Bailes, Amanda
2003 Sep;12(9):1545-1558, Expert opinion on investigational drugs
— id: 44834, year: 2003, vol: 12, page: 1545, stat: Journal Article,

Treatment of refractory cancer with Taxol using Cyclosporine A and Megace to reverse multidrug resistance
Adams S; Cabeza R; Garrison M; Keltz J; Gervasoni J; Hindenburg A
2000 ;19:213-213 Abstract #213, Proceedings (American Society of Clinical Oncology)
— id: 73376, year: 2000, vol: 19, page: 213, stat: Journal Article,