Michael Scher
732-246-9900

Michael Scher (2003 - 2007) Postdoctorate Research with Rosetta Genomics, Inc., New Brunswick, New Jersey Publications: Human SirT1 Interacts with Histone H1 and Promotes Formation of Facultative Heterochromatin Vaquero, A., Scher, M., Lee, D., Erdjument-Bromage, H., Tempst, P., and Reinberg, D. Molecular Cell (2004) 16, 93-105 Composition and Histone Substrates of Polycomb Repressive Group Complexes Change During Celluar Differentiation Kuzmichev, A., Margueron, R., Vaquero, A., Preissner, T.S., Scher, M., Kirmizis, A., Ouyang, X., Brockdorff, N., Abate-Shen, C., Farnham, P., and Reinberg, D. PNAS (2005) 102, 1859-1864 Biochemistry of Multiprotein HDAC Complexes Vaquero, A., Scher, M., and Reinberg, D. Histone Deacetylases: Transcription Regulation and Other Cellular Functions. (ed. E. Verdin) Humana Press, NJ (2006) 23-60 SirT2 is a Histone Deacetylase with Preference for Histone H4 Lys 16 During Mitosis Vaquero, A., Scher, M.B., Lee, D.H., Sutton, A., Cheng, H.L., Alt, F.W., Serrano, L., Sternglanz, R., and Reinberg, D. Genes Dev. 2006, May 15; 20 (10): 1256-1261; Epub 2006, Apr 28 PMID: 16648462 (PubMed - indexed for MEDLINE) Vaquero, A., Scher, M., Erdjument-Bromage, H., Tempst, P., Serrano, L. and Reinberg, D. (2007). SIRT1 regulates the histone methyl-transferase SUV39H1 during heterochromatin formation. Nature, 450,440-444.