| Role of MYH9 in Hearing and Deafness
Anil K. Lalwani M.D.
Mendik Foundation Professor of Otolaryngology and Chairman and Professor of Physiology and Neuroscience
Departments of Otolaryngology and Physiology and Neuroscience Member of NYU Otolaryngology Associates |
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| Research Summary |
| We have recently identified MYH9, a non muscle heavy chain myosin, as the gene responsible for DFNA17 (autosomal dominant hearing impairment). Currently, we are assessing the consequences of specific MYH9 mutations on protein function, its contribution to human deafness, and are utilizing knock-out and knock-in transgenic mouse models to assess its role in normal hearing. |
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| Research Information |
Research Interests | Molecular genetics of deafness
Gene therapy for deafness | Research Keywords | genetics, molecular biology, deafness, gene therapy |
