Program:
The Conference will be held at the New York University School
of Medicine for two days; on Friday, November 5 and Saturday,
November 6, 1999. Each day is divided into 3 topical sessions
of approximately 90 minutes of presentations and 30 minutes of
discussion. The relatively large allocation of time to discussion
is an intended feature of the Conference format, which anticipates
the value of a dynamic interaction among the presenters. The
role of the moderators will be to introduce speakers, mediate
questions from the audience, and facilitate the discussion with
their own questions and views. A syllabus will be prepared that
will contain the program and abstracts, and additionally provide
speakers with the option of including material such as tables,
figures, or selected reprints, in order to facilitate audience
assimilation and the maintenance of brevity of presentations
by providing ready reference to key material. In addition, a
syllabus will provide a useful preliminary organizing principle
in the process of developing a publication of the conference
proceedings.
Friday, Nov. 5, 1999
8:00 a.m.-9:00 a.m.
Breakfast and registration
9:00 a.m.-9:10 a.m.
Introductory remarks R. Cancro
9:10 a.m.-9:40 a.m.
"NIDA's role in the development of ibogaine"
F. Vocci
9:40 a.m.- 11:20 a.m.
Session 1: Mechanisms of Action I
Presentations:
"Ibogaine actions on the NMDA receptor" P.
Skolnick
"Glutaminergic systems in the brain and addictive disorders:
Medications development" B. Herman
"Mechanisms of action of ibogaine relevant to its putative
clinical effects" S. Glick
"Changes in gene expression and signal transduction following
ibogaine treatment"-E.S. Onaivi
11:20 a.m.-11:50 a.m.
Session 1 Discussion
Moderators: E. Simon and M. Baumann
11:50 a.m.-1:00 p.m.
Lunch
1:00 p.m.-2:20 p.m.
Session 2: Mechanisms of Action II
Presentations:
"Comparative neurobiology of ibogaine and noribogaine"
M. Baumann
"Drug discrimination studies with ibogaine" S. Helsley
"Characterization of multiple sites of action of ibogaine"
H. Sershen
2:20 p.m.-2:50 p.m.
Session 2 Discussion
Moderator: S. Glick
2:50 p.m.-3:10p.m.
Break
3:10 p.m.-4:50p.m.
Session 3: Clinical and Preclinical Pharmacolgy: Efficacy
and Safety
Presentations:
"Mechanisms of Neurotoxicity" M. Molliver
"Sigma receptors and iboga alkaloids: Sigma 2 receptors
mediate ibogaine induced changes in intracellular calcium and
aptotic cell death" W. Bowen
"Neurotoxicology of ibogaine" S. Ali
"Ibogaine in acute opioid withdrawal: Case series from the
informal treatment context" K. Alper
"Informal treatment with ibogaine in Slovenia" A. Kastelic
4:50 p.m.-5:20 p.m.
Session 3 Discussion
Moderator: F. Vocci
Saturday, November 6, 1999
8:00 a.m.-9:00 a.m.
Breakfast and registration
9:00 a.m.-10:20 a.m.
.Session 4: Learning, Memory, and Neurophysiology
Presentations:
"Ibogaine, place preference and opioid tolerance"
L. Parker
"Ibogaine, Learning and memory" P. Popik
"Ibogaine and the EEG" Z. Binienda
"Neurologic and electroencephalographic observations during
ibogaine treatment" D. Luciano
10:20 a.m.-10:50 a.m.
Session 4 Discussion
Moderator: S. Siegel
10:50 a.m.-11:10 a.m.
Break
11:10 a.m.-12:30 p.m.
Session 5: Ethnographic and Sociological Methods
Presentations:
"Bio-sociocultural understanding of the use of Eboga"
J. Fernandez
and R. Fernandez
"Technology transfer and Tabernanthe iboga treatments: the
application of relevant traditional Bwiti techniques to a western
medical setting" D. Lieberman
"An ibogaine focus group" C. Kaplan
12:30 p.m.-1:00 p.m.
Session 5 Discussion
Moderator: M. Galanter
1:00 p.m.-2:00 p.m.
Lunch
2:00 p.m.-3:30 p.m.
Session 6: Political, Historical, and Economic Perspectives.
Presentations:
"Ibogaine and the lessons of the history of psychedelics"
R. Jones
"From the roots up: Ibogaine and addict self-help"
G. Frenken
"Incentives and disincentives to drug development: The case
of ibogaine" W Schmidt
"Ibogaine in informal and conventional treatment contexts:
Implications for patient management" H. Lotsof
3 :30 p.m.- 4:00 p.m.
Session 6 Discussion
Moderator: H. Kleber
4:00 p.m.-4:10 p.m.
Closing Remarks K. Alper
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