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Archive of Featured Research Articles and Reviews

March 2008  
Treatment eligibility and outcomes in elderly patients with chronic hepatitis C: results from the VA HCV-001 Study. Edmund Bini, et al:
Gastroenterology
Tolerance and activity of oxaliplatin with protracted topotecan infusion in patients with previously treated ovarian cancer. A phase I study. Franco Muggia, et al: Medical Oncology
Care coordination to increase referrals to smoking cessation telephone counseling: a demonstration project. Scott Sherman, et al: General Internal Medicine
February 2008  
Platelet fragmentation requires a specific structural conformation of human monoclonal antibody against beta3 integrin.

Simon Karpatkin, et al:
Hematology

Variance estimation in complex survey sampling for generalized linear models . Sundar Natarajan, et al:
General Internal Medicine
Tobacco use behaviors and household smoking bans among Chinese Americans. Donna Shelley, et al:
General Internal Medicine
January 2008  
Initiation of the adaptive immune response to Mycobacterium tuberculosis depends on antigen production in the local lymph node, not the lungs. Joel Ernst, et al: Infectious Diseases and Immunology
Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis. John Munger, et al: Pulmonary and Critical Care Medicine
To Err is Human Continued: A Failure of Follow-up. Craig Tenner, et al: General Internal Medicine
December 2007  
Gap junction remodeling and cardiac arrhythmogenesis in a murine model of oculodentodigital dysplasia. Glenn Fishman, et al: Cardiology
Adenosine A2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway. Jiantu Che, et al: Clinical Pharmacology
Paradoxical septal motion after cardiac surgery: a review of 3,292 cases. Harmony Reynolds, et al: Cardiology
The relationship between the initiation of antimicrobial therapy and the incidence of stroke in infective endocarditis: an analysis from the ICE Prospective Cohort Study (ICE-PCS). Stuart Dickerman, et al: Cardiology
November 2007  
The effects of torture-related injuries on long-term psychological distress in a Punjabi Sikh sample. Andrew Rasmussen, et al: General Internal Medicine
Racial/ethnic differences in patient experiences with and preferences for computed tomography colonography and optical colonoscopy. Edmund Bini, et al: Gastroenterology
Abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor. Gregory Morley, et al: Cardiology
October 2007  
Distal airway function in symptomatic subjects with normal spirometry following World Trade Center dust exposure. Kenneth Berger, et al: Pulmonary and Critical Care Medicine
Dendritic cells in the kidney. Rohan John and Peter Nelson
Presentation and outcome of hepatocellular carcinoma in HIV-infected patients: a U.S.-Canadian multicenter study. Edmund Bini, et al: Gastroenterology

September 2007
 
Effect of homocysteine lowering on mortality and vascular disease in advanced chronic kidney disease and end-stage renal disease: a randomized controlled trial. David Goldfarb, et al: Nephrology
Function of NKT cells, potential anti-HIV effector cells, are improved by beginning HAART during acute HIV-1 infection. Michael Poles, et al: Gastroenterology
Platelet particle formation by anti GPIIIa49-66 Ab, Ca2+ ionophore A23187, and phorbol myristate acetate is induced by reactive oxygen species and inhibited by dexamethasone blockade of platelet phospholipase A2, 12-lipoxygenase, and NADPH oxidase. Simon Karpatkin, et al: Hematology

August 2007
 
Mycobacterium tuberculosis infects dendritic cells with high frequency and impairs their function in vivo. Joel Ernst, et al: Infectious Diseases and Immunology
Effectiveness of an on-call counselor at increasing smoking treatment. Scott Sherman, et al: General Internal Medicine
Improving journal club presentations, or, I can present that paper in under 10 minutes. Mark Schwartz, et al: General Internal Medicine

July 2007
 
Virus-induced cellular immune mechanisms of injury to the kidney. Peter Nelson, MD and Jason Faulhaber: Nephrology
Health services for HIV/AIDS, HCV, and sexually transmitted infections in substance abuse treatment programs. Edmund Bini, et al: Gastroenterology
A simple method of determining confidence intervals for population attributable risk from complex surveys. Sundar Natarajan, MD, et al: General Internal Medicine

June 2007
 
Ozone, a malady for all ages.
William Rom, MD, et al: Pulmonary and Critical Care Medicine
Factor structure of PTSD symptoms among West and Central African refugees. Andrew Rasmussen, PhD, et al: General Internal Medicine
Association between chronic hepatitis B virus infection and diabetes among Asian Americans and Pacific Islanders. Ann Danoff, MD, Edmund Bini, MD, et al: Endocrinology and Gastroenterology

May 2007
 
Breast cancer from oral and transdermal estradiol: a cohort study of Finnish women Tanping Wong, MD and Nirav Shah, MD: General Internal Medicine
Medical training in school-based health centers: collaboration among five medical schools. Adina Kalet, MD, et al: General Internal Medicine
Prevalence and impact of diarrhea on health-related quality of life in HIV-infected patients in the era of highly active antiretroviral therapy. Michael Poles, MD, Edmund Bini, MD, et al: Gastroenterology

April 2007
 
Using trigger phrases to detect adverse drug reactions in ambulatory care notes. Cantor MN, Feldman HJ, Triola MM: General Internal Medicine
Adverse metabolic side effects of thiazides: implications for patients with calcium nephrolithiasis. Huen SC, Goldfarb DS: Nephrology
Mechanisms of action of acetazolamide in the prophylaxis and treatment of acute mountain sickness. Leaf DE, Goldfarb DS: Nephrology

February - March 2007
 
On-site medical care in methadone maintenance: associations with health care use and expenditures. Marc Gourevitch, MD, et al: General Internal Medicine
Expression of a sorcin missense mutation in the heart modulates excitation-contraction coupling. Glenn Fishman, MD, et al: Cardiology
Review: Endarterectomy Is Superior to Stenting in Patients with Symptomatic Severe Carotid Stenosis. Michael Janjigian, MD, and Nirav Shah, MD: General Internal Medicine
Evaluation of the abdominal aorta and the renal arteries with an intracardiac echocardiography probe placed in the inferior vena cava: a feasibility study. Itzhak Kronzon, MD, et al: Cardiology
Pegylated liposomal doxorubicin HCL (PLD; Caelyx/Doxil®): Experience with long-term maintenance in responding patients with recurrent epithelial ovarian cancer. Eleni Andreopoulou, MD, et al: Medical Oncology

January 2007
 
Mechanisms of gastrointestinal CD4+ T-cell depletion during acute and early human immunodeficiency virus type 1 infection. Michael Poles, MD, et al: Gastroenterology
Bridging the inferential gap: the electronic health record and clinical evidence. Nirav Shah, MD, et al: General Internal Medicine
Computers in the exam room: differences in physician-patient interaction may be due to physician experience. Mark Schwartz, MD, et al: General Internal Medicine

December 2006
 
Histidine phosphorylation of the potassium channel KCa3.1 by nucleoside diphosphate kinase B is required for activation of KCa3.1 and CD4 T cells. Edward Skolnik, MD, et al: Nephrology
Brief report: beta-blocker use among veterans with systolic heart failure. Mark Schwartz, MD, et al: General Internal Medicine
Current breast cancer risks of hormone replacement therapy in postmenopausal women. Nirav Shah, MD and Tanping Wong, MD: General Internal Medicine

November 2006
 
Thrombin induces tumor growth, metastasis, and angiogenesis: Evidence for a thrombin-regulated dormant tumor phenotype Simon Karpatkin, MD and Mary Lynn Nierodzyk, MD: Hematology
Economic Implications of Non-Adherence to Treatment Recommendations for Hemodialysis Patients with Anemia David Goldfarb, MD, et al: Nephrology
Characterization of the divergent wound-healing responses occurring in the pathergy reaction and normal healthy volunteers Stephen Oliver, MD, et al: Clinical Pharmacology

October 2006
 
Coronary Intervention for Persistent Occlusion After Myocardial Infarction Judith S. Hochman, MD, et al: Cardiology
Properties of a versatile nanoparticle platform contrast agent to image and characterize atherosclerotic plaques by magnetic resonance imaging Edward A. Fisher, MD, et al: Cardiology
Predictive value of a positive fecal occult blood test increases as the severity of CKD worsens Edmund J. Bini, MD, et al: Gastroenterology

September 2006
 
Who are we? Indigenous microbes and the ecology of human diseases Martin J. Blaser, MD: Infectious Diseases and Immunology
National multicenter study of HIV testing and HIV seropositivity in patients with chronic hepatitis C virus infection Edmund J. Bini, MD, et al: Gastroenterology
Multicenter, randomized, controlled trial of virtual-reality simulator training in acquisition of competency in colonoscopy Jonathan Cohen, MD, et al: Gastroenterology
Defining, navigating, and negotiating success: the experiences of mid-career Robert Wood Johnson Clinical Scholar women Adina Kalet, MD, et al: General Internal Medicine

August 2006
 
Use of flexible sigmoidoscopy to screen for colorectal cancer in HIV-infected patients 50 years of age and older Edmund J. Bini, MD, et al: Gastroenterology
Adenosine A2A receptors in diffuse dermal fibrosis: pathogenic role in human dermal fibroblasts and in a murine model of scleroderma Edwin Chan, MD, et al: Clinical Pharmacology
Lack of decay of HIV-1 in gut-associated lymphoid tissue reservoirs in maximally suppressed individuals Michael Poles, MD, et al: Gastroenterology

July 2006
 
Effect of implementing pain management standards Daniel Shine, MD, et al: General Internal Medicine
Improving access to sterile syringes and safe syringe disposal for injection drug users in methadone maintenance treatment Marc Gourevitch, MD, et al: General Internal Medicine
Adenosine A2A receptors play a role in the pathogenesis of hepatic cirrhosis Edwin Chan, MD, et al: Clinical Pharmacology

June 2006
 
Diesel exhaust particle-exposed human bronchial epithelial cells induce dendritic cell maturation Bertram Bleck, MD, et al: Pulmonary and Critical Care Medicine
Early revascularization and long-term survival in cardiogenic shock complicating acute myocardial infarction Judith Hochman, MD, et al: Cardiology
Impact of human immunodeficiency virus infection on the prevalence and severity of steatosis in patients with chronic hepatitis C virus infection Edmund J. Bini, MD, et al: Gastroenterology